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PICAMILON ® (Nicotinoyl-GABA)
51 Reviews
Picamilon Information
INN: | N-nicotinoyl-gamma-aminobutyric acid |
Chemical name of Picamilon: | Sodium salt of N-nicotinoyl-g-aminobutyric acid |
Form: | Pills (20 mg and 50 mg) |
Active ingredient: | Picamilon or N-nicotinoyl-GABA – 20mg or 50 mg |
Excipients: | Potato starch, magnesium hydroxycarbonate hydrate, talc, sucrose, stearic acid or calcium stearate. |
CAS Number: | 34562-97-5 |
Molecular formula: | C10H12N2O3 |
ATC code: | N06BX Nootropic |
Pharmacological action: | Tranquilizing, psycho-stimulating, antiaggregant, antioxidant |
Bioavailability: | From 50 to 88% |
Half-life: | 30 min |
Shelf life: | 3 years. Do not use beyond the expiration date printed on the package. |
Storage conditions: | Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children. |
Manufacturer: | PharmStandard, https://pharmstd.com/ |
What is Picamilon?
Picamilon Sodium (Pikamilon) is a nootropic compound that was synthesized in the USSR in the middle of the 1960s to support brain health and help with anxiety and insomnia. And it has been used as a treatment for neurological problems since then.
Picamilon is based on a synthetic combination of GABA and niacin. Gamma-aminobutyric acid in Picamilon is responsible for reducing neuronal excitability. And niacin acts as a strong vasodilator.
This unique blend has been shown to have a variety of benefits for the mind and body. Some of these benefits include improved mood, better brain function, protection against Alzheimer’s disease, and regulation of cerebral blood flow.
What is Picamilon Used For?
- Cerebrovascular diseases;
- Anxiety;
- Migraine;
- Asthenic disorders (lack of energy);
- Mild depressions;
- Alcohol withdrawal syndrome.
Picamilon Safety Precaution
As with human consumption of any new supplement, it is important to do your research before taking Picamilon. Be sure to consult with a healthcare professional if you have any questions or health concerns.
A well-known biohacker Lucas Aoun reviews Picamilon on YouTube – click below
What are the Effects of Picamilon?
As the official instruction claims, Picamilon dilates blood vessels in the brain. [2] It also has tranquilizing, psychostimulating, antiaggregant, and antioxidant effects. Picamilon nootropic can improve the functional state of the brain due to the normalization of tissue metabolism and its influence on cerebral circulation. The listed effects include increased volume and linear speed of cerebral blood flow, reduced resistance of cerebral vessels, suppressed platelet aggregation, and better microcirculation.
After a full treatment course under the doctor’s supervision, Picamilon is said to increase physical and mental efficiency, reduce headaches, and normalize sleep. Anecdotal reports on Picamilon reddit say that it can contribute to the reduction of anxiety, tension, and fear.
Where to Buy Picamilon?
Although it is not a verified dietary supplement in the USA, consumers can easily buy Picamilon online. If you want to purchase Picamilon, buy it at CosmicNootropic. It’s a reliable vendor that offers high-quality nootropics and supplements to improve brain function, reduce anxiety and enhance general well-being.
Legal Disclaimer
All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using Picamilon consulting a qualified MD is mandatory. See more
Picamilon Dosage
Dosages of Picamilon and course duration depend on the patient’s condition and your doctor’s recommendations. The typical daily dose for pills is 30–50 mg, once or twice a day. Picamilon injection dosage varies from 100 to 200 mg once a day.
To learn more about the Picamilon dosage please read the official instructions below.
Picamilon Side effects
Side effects occur in approximately 12% of patients and are characterized by decreased blood pressure, dizziness, headache, mild nausea, irritability, agitation, anxiety, and allergic reactions (skin rash, itching).
Сonsuming too much Picamilon may increase potential side effects.
Picamilon vs Phenibut: What’s the Difference?
Picamilon is an “older brother” of Phenibut. They have similar properties, but they are not the same.
Both drugs reduce anxiety and improve mood. However, unlike Phenibut, Picamilon is said to have a much stronger impact on energy metabolism in the brain because it stimulates the consumption of oxygen and glucose by the neuronal tissue.
Like Phenibut, Picamilon shall not be taken for a period longer than 3 weeks. And both can cause withdrawal syndrome if abused.
OFFICIAL INSTRUCTION of Picamilon Pills
OFFICIAL INSTRUCTION of Picamilon Injections
- Voznesenskii et al (1989) Comparative study of the effect of picamilone and piracetam on learning in rats in a radial maze https://www.unboundmedicine.com/medline/citation/2806520/
- I Sapegin, A Beketov (1993) The effect of pikamilon and fenibut on the blood supply of the brain at rest and under gravitational exposures https://www.ncbi.nlm.nih.gov/pubmed/8324468
- Shyman’kyi et al (2002) Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy https://www.ncbi.nlm.nih.gov/pubmed/12916162
- Kuchmerovs’ka et al (2003) State of GABA-benzodiazepine receptor complex in diabetic neuropathy: effect of nicotinamide and nicotinoyl-GABA https://www.ncbi.nlm.nih.gov/pubmed/14577176
- Silkina et al (2005) Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon https://www.ncbi.nlm.nih.gov/pubmed/15786959
- Likhodeev et al (2009) Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome https://www.ncbi.nlm.nih.gov/pubmed/19803364
- Avula et al (2016) Identification and quantification of vinpocetine and picamilon in dietary supplements sold in the United States https://www.ncbi.nlm.nih.gov/pubmed/26426301
- Zakharov et al (2022) Treatment of patients with chronic cerebral ischemia: experience of using the combined neuroprotective drug Picamilon Ginkgo https://pubmed.ncbi.nlm.nih.gov/36168693/
- M Santillo, R Sprando (2023) Picamilon, a γ-aminobutyric acid (GABA) analogue and marketed nootropic, is inactive against 50 biological targets https://pubmed.ncbi.nlm.nih.gov/36668678/
4.3
Based on 51 Reviews
(36)
(3)
(5)
(3)
(4)
05/02/2024
Catherine W.
Verified BuyerUS
PICAMILON: Helped then hurt
I took Picamilon to avert depression and anxiety I experienced prior to having post menopausal hot flashing. And during the first 6 weeks it worked just fine. Then I started to have the sensation that I was going to faint, and had to sit down quickly. This happened several times until I quit taking Picamilon. It took about 4 days to have these effects clear my system. I am afraid to take more of this product because of these near fainting spells.
05/02/2024
Hi Catherine! We are sorry to hear about this. While some individuals may find certain nootropics helpful in managing specific symptoms, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan tailored to your specific needs. The effect of most nootropics varies from person to person, depending on the personal conditions, so you should definitely consult a doctor on this matter.
05/02/2024
Lauren C.
Verified BuyerUS
Picamilon works
We were recommended the use of this product to calm and adjust GABA for my husband. He has high anxiety due to PFS. This appears to blunt some of that anxiety when taken. It does have some getting used to, but definitely calms some of the chaos. Be aware, it could feel like it blunts emotions which is normal.
05/02/2024
Hi Lauren! Thank you for leaving your review and sharing your thoughts on the product.
04/28/2024
Grace M.
Verified BuyerCA
It was not what I was expecting but maybe should have done more research
Not bad but I was going for a specific effect and its not the product, it was more me trying something new
04/28/2024
Dear Grace, Thank you for sharing your experience. It's great to hear that you were open to trying something new. If you ever need more information, feel free to reach out. We're here to help!
04/22/2024
John C.
Verified BuyerUS
Effective GABA
Enhance good rest and clarity the following day.
04/22/2024
Dear John, thank you for sharing your thoughts on this product!
04/07/2024
Bodie S.
Verified BuyerUS
Solid
As far as i can tell theyre good potent products
04/12/2024
Hi Bodie! Thank you for your positive review :)
04/01/2024
Mark S.
Verified BuyerUS
Where's my stuff ?
I ordered pills/caps of picamilim and received ampules instead. I returned them but have not received anything! I didn't ask for a refund. Just a replacement. Received zero! Scammed again!
04/02/2024
Hi Mark! We are so sorry to hear about this puzzling situation. We have emailed you to see how we can resolve this issue.
03/22/2024
Brian G.
Verified BuyerUS
Very helpful
I expected a mental boost, but was not expecting the positive mood boost too. I will buy it again asap.
03/22/2024
Dear Brian, we are happy that Picamilon has had this positive effect on you :)
03/11/2024
ROCCO R.
Verified BuyerCA
Picamilon for Tinnitus
I bought this to try and treat my Tinnitus. I think it improved slightly.
03/14/2024
Dear Rocco, thank you for your feedback! We're glad to know it's working for you :)
03/02/2024
David O.
Verified BuyerUS
A+ Customer Service, and.....
I am already seeing positive effects from the picamilon.
03/03/2024
Dear David, We're thrilled to receive your A+ rating for our customer service! Even more exciting is hearing about the positive effects you're experiencing with Picamilon. Thanks for choosing us!
03/02/2024
Timothy K.
Verified BuyerUS
picamilon
very interesting, very safe and pharmacologically interesting substance.
03/03/2024
Dear Timothy, We're delighted to hear your positive take on Picamilon. Your insights are valued!
02/20/2024
Lyal S.
Verified BuyerUS
Good stuff, but website is ******* up
It seemed to help me a bit. I noticed a elevation in mood, and also drive. Would like to order some more but could not enter financial account information.
02/21/2024
Dear Lyal, thank you for sharing your experience with us! We are glad you like our product.
01/26/2024
ROCCO R.
Verified BuyerCA
I have not received it yet
It was shipped on Dec 10 and I still dont have it. It landed at the New York Postal Facility which then sent the package to Egypt for some reason. I have not heard anything yet so I assume its still in Egypt.
01/26/2024
Dear Rocco, we are so sorry that your order is taking long to arrive. We have contacted you through email to see what we can do in this situation. Please check!
01/25/2024
Tammy L.
Verified BuyerUS
Love it!
Finally sleeping through the night
01/26/2024
Hi Tammy! Thank you for sharing your experience with us. We are glad that you liked the product!
01/18/2024
Mark B.
Verified BuyerUS
Picamilon
Great products,Great company thank you very much!!!
01/20/2024
Hi Mark! We are thrilled to hear that you are happy with our products and service! Thank you:)
01/14/2024
Greg D.
Verified BuyerUS
Good product.
This product has worked well (as expected and even better). Its made a positive difference. Recomended 5/5.
01/14/2024
Dear Greg, Thank you for letting us and the community know about your experience! We hope to see you as our customer again.
11/05/2023
K. M.
Verified BuyerUS
Really works!
Interesting pill. Taking less doesn't make me feel much, but if I take one or two 50mg, after I awake it gives me slight energy and relieves anxiety. I was have some issues with anxiety, and when I take these, plus sometimes pregabalin (I am prescribed it from my doc), I feel fine. I don't overdue it though, and make sure I leave at least 3 hours after taking it before I have a drink. At any rate, this is very subtle yet effective. I am ordering more.
11/05/2023
Thanks for the detailed feedback! We're glad Picamilon works well for you ☺️
11/02/2023
Jared S.
Verified BuyerCA
Super Calming
Super relaxing, great sleep on this. Definitely boosts the effects of other tranquilizing Or stimulating nootropics in a way. My anxious partner loves it for studying, helps her focus.
11/03/2023
Dear Jared, we're glad to hear that Picamilon has had a positive impact on your and your partner's life!
10/22/2023
Kelly L.
Verified BuyerUS
Excellent supplement
Great product. I will be buying again. Really helps with restless legs or issues sleeping. Lowers anxiety at night and has a nice sedative effect. And unlike alcohol, I don't believe that this effects sleep in a negative way... as far as I can tell, it makes it better.
10/25/2023
Dear Kelly, thank you for sharing your experience, we are glad you are satisfied with our product!
09/08/2023
Martin
Verified BuyerUS
Less is more
Oddly, I experience a pronounced anxiolytic and relaxing effect if I take a quarter of one tablet. When I tried taking a whole one, I didn\'t feel anything. Can\'t explain it, but that\'s how it works for me.
09/08/2023
Hi Martin! We're glad the product works for you! For most nootropics, the effect can be varied for different people and sometimes for the same person in different situations. It always depends on many conditions.
Thank you!
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