Approved labelSYMLINPEN prescribing information as an adjunct to mealtime insulin
PopulationAdults with type 1 or type 2 diabetes covered by the approved indication
DoseType 1 diabetes starts at 15 mcg before major meals with label-directed 15 mcg increases. Type 2 diabetes starts at 60 mcg before major meals and may increase to 120 mcg if tolerated. The label also directs a 50% initial reduction in mealtime insulin.
RouteSubcutaneous injection in the abdomen or thigh, separate from insulin injections
FrequencyImmediately before major meals containing at least 250 calories or 30 grams of carbohydrate
DurationLong-term adjunctive use with label-directed glucose monitoring and titration
PreparationReady-to-use 1000 mcg/mL solution in SymlinPen 60 and SymlinPen 120 multidose pens; no reconstitution.