Proven
Phosphatidylserine
The prediction game
Call it: rising or fading?
Where does Phosphatidylserine stand 12 months from now? Lock your call with a confidence level. When the window closes, the Brier rule scores your calibration: right and confident earns the most, wrong and confident costs the most. Points and a leaderboard spot are the whole prize. No stakes, no money.
One call per intervention. It locks the moment you submit: no edits, no cancels. It resolves when the 12-month window closes.
The Crowd’s Call
Rising or fading over the next 12 months? Lock your call and find out if you saw it coming.
Community Signal
No weigh-ins yet. Be the first and set the early signal.
Evidence
Evidence grade: C (mixed evidence)
Graded from the strength of the published research, independent of any verdict on this page.
Evidence Anchor
BioHarmony 7.3/10
Phosphatidylserine is a 7.3 / 10 fit for cognition focus, memory, stress resilience, especially for readers who can match the protocol to cortisol pattern, cognitive baseline, training stress, and soy or sunflower source. The best evidence anchors are [Duan et al. 2025](https://www.sciencedirect.com/science/article/pii/S0165032724016203), which 190 randomized MCI patients; positive cognitive findings from a multi-ingredient formula, so PS-specific attribution is not separable, and [Friling et al. 2025](https://link.springer.com/article/10.1186/s12937-025-01264-9), which 209 randomized healthy children; no total-cohort primary or secondary outcome differences; subgroup signal for lower baseline cognitive performance. Phosphatidylserine is a targeted phospholipid supplement with its best evidence in older adults with memory complaints and stress-linked cortisol regulation. ✅ Best for: Adults 55+ with age-associated memory complaints who want a low-risk 300 mg/day trial and understand that the strongest evidence comes from older BC-PS trials, not necessarily the sunflower or soy PS bottle on today's shelf. Chronically stressed adults with high cortisol tone who want an HPA-axis support tool. Athletes in heavy blocks testing 600 mg/day for exercise-cortisol modulation per Starks 2008. Children with ADHD-like inattention only as an adjunct under clinician oversight, especially when omega-3 status is addressed. ❌ Avoid if: You are a young healthy adult without memory decline, high stress reactivity, ADHD-like inattention, or heavy training load. The expected cognitive upside is small and other interventions usually win. Avoid soy-derived PS if you have soy allergy; use sunflower PS instead. Avoid unsupervised pediatric use, pregnancy use, and anticoagulant or antiplatelet co-use without clinician input. Avoid PS as a dementia treatment substitute. FDA's claim is qualified and narrow, EFSA rejected a soy-PS cognition claim, and Alzheimer's Association experts do not currently recommend PS for Alzheimer's disease.
Read the full BioHarmony report
My score and my verdict: one signal of three, never the whole answer.
Momentum
Signals begin with Edition 2
Direction needs two weekly snapshots to compare, so the arrows stay off until the next edition. Attention tracking is already running.
Momentum = how fast attention is rising across search, Reddit, PubMed, podcasts, and curated industry newsletters this week; it can flag an item as Overhyped/Fading, but it never overrides the evidence behind Proven. How momentum works.
- Ring
- Proven
- Trend
- Begins with Edition 2
- Momentum
- 5.9%
- BioHarmony Score
- 7.3/10
- Last Updated
- Jul 2, 2026
Sources
- BioHarmony score
- Search trend delta
- Reddit velocity
- PubMed publication count
- Podcast mention frequency
- Curated newsletter mentions
The score anchors the ring; the other five drive momentum, which can nudge the ring by one step at most. How placement works.
Weigh In
Your input feeds the community signal shown beside my verdict. It informs the board and it never sets the score by itself. How community input works.
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