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Health Optimization Index

Sabroxy (Oroxylum indicum Extract)

Nick’s assessment
Promising
Research evidence
C, mixed evidence
Attention
16.7 / 100▲ Rising this week
6.6/ 10

BioHarmony score

Sabroxy is a dopamine-leaning botanical nootropic with one main human cognition trial at 500 mg/day (Lopresti 2021). The practical signal is focus without heavy next-day depletion for some users, but replication and sleep timing remain the constraints.

Read the full report Benefits, risks and practical guidance.

Read Nick’s assessment Why it earned this rating

Sabroxy is a standardized Oroxylum indicum extract worth a focused trial if you want clean, dopamine-leaning attention support and you understand the human evidence is essentially one 28-day trial. It makes the most sense for cognitive and mood goals, where a reversible MAO-B mechanism and the Lopresti et al. 2021 trial both point. Outside that lane the support thins out fast, so match it to a specific goal, buy a properly standardized product, and track a concrete before-and-after rather than chasing a general boost.

✅ Best for: Adults who want daytime focus and motivation without the jitter and next-day depletion of harder stimulants, and who can keep dosing early so sleep stays intact. It fits people testing a plant-derived alternative to caffeine or modafinil who will run a short, tracked experiment and stop if it does not deliver.

❌ Avoid if: Avoid Sabroxy during pregnancy or breastfeeding, if you take antidepressants, MAO inhibitors, or other dopamine or serotonin drugs without medical sign-off, or if you are sensitive to stimulants or have a heart condition. Athletes in tested sports should confirm their rules first, and no one should use it as a substitute for sleep, training, nutrition, or proper medical care.

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Updated Sep 21, 2026 How the Index ranks →

Educational information, not medical advice. Ask a qualified clinician about risks and interactions. Independent ratings: no affiliate links, sponsored placements or paid rankings.