Approved labelDesmopressin acetate injection prescribing information for central diabetes insipidus and specified bleeding disorders
PopulationAdults and pediatric patients covered by the approved injection indications
DoseCentral diabetes insipidus uses 2-4 mcg/day in one or two divided doses. Hemophilia A and type 1 von Willebrand disease use 0.3 mcg/kg to a maximum of 20 mcg by intravenous infusion.
RouteSubcutaneous or intravenous injection for diabetes insipidus; intravenous infusion for the labeled bleeding-disorder indications
FrequencyIndication-specific; one or two divided daily doses for diabetes insipidus
DurationIndication-specific use with fluid, sodium, and clinical monitoring
PreparationReady-to-use 4 mcg/mL solution. For IV infusion in hemophilia A or type 1 von Willebrand disease, dilute doses of 10 mcg or less in 10 mL of 0.9% sodium chloride and doses over 10 mcg in 50 mL, then infuse over 15-30 minutes.