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Experimental · 4.1/10

FOXO4-DRI

Evidence E · thin evidence ▲ 19.8% momentum 🥇 First scout open
4.1/ 10

FOXO4-DRI is a designed senolytic peptide that kills senescent cells by breaking the FOXO4 to p53 bond, famous for restoring fur and kidney function in aged mice per Baar 2017. It has zero human trials, no registered study, and grey-market-only sourcing, so it scores 4.2 in Caution. Read the full breakdown →

The prediction game

Where does FOXO4-DRI go in 12 months?

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The Crowd’s Call

Rising or fading over the next 12 months? Lock your call and find out if you saw it coming.

Your 12-month call on FOXO4-DRI

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Be the first scout on record for FOXO4-DRI. Permanent credit on this page, plus points when your call resolves.

One call per intervention. It locks the moment you submit (no edits, no cancels) and resolves in 12 months. See the scout leaderboard →

Weigh In

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Which ring does it deserve?

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Related reading

Ring Experimental Momentum 19.8% Updated Jul 20, 2026 How the Index ranks →

Verdict by Nick Urban, host of the High Performance Longevity podcast.

For education only, not medical advice. Supplements, peptides, and protocols can interact with medications and conditions. Talk to a qualified clinician before starting anything here.