Promising · 6.7/10
Apigenin
Apigenin is a chamomile-derived flavonoid with a credible GABA-A calming mechanism and modest human anxiety evidence from chamomile extract trials, especially Mao 2016 and Amsterdam 2009. Pure isolated apigenin still lacks adequate human RCTs for sleep, anxiety, testosterone, or NAD+. The popular 50 mg sleep dose is mixed in practice: some people get real calm, many feel nothing, and chronic 100+ mg use has a reversible mood-blunting signal. Read the full breakdown →
The prediction game
Where does Apigenin go in 12 months?
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The Crowd’s Call
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One call per intervention. It locks the moment you submit (no edits, no cancels) and resolves in 12 months. See the scout leaderboard →
Weigh In
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For education only, not medical advice. Supplements, peptides, and protocols can interact with medications and conditions. Talk to a qualified clinician before starting anything here.