Proven
Lion's Mane
The prediction game
Call it: rising or fading?
Where does Lion's Mane stand 12 months from now? Lock your call with a confidence level. When the window closes, the Brier rule scores your calibration: right and confident earns the most, wrong and confident costs the most. Points and a leaderboard spot are the whole prize. No stakes, no money.
One call per intervention. It locks the moment you submit: no edits, no cancels. It resolves when the 12-month window closes.
The Crowd’s Call
Rising or fading over the next 12 months? Lock your call and find out if you saw it coming.
Community Signal
No weigh-ins yet. Be the first and set the early signal.
Evidence
Evidence grade: B (good evidence)
Graded from the strength of the published research, independent of any verdict on this page.
Evidence Anchor
BioHarmony 7.2/10
Lion's Mane is a 7.2 / 10 fit for people testing a gentle cognition or mood mushroom with realistic expectations and enough patience for multi-week tracking, not a guaranteed nerve-regrowth or dementia treatment. The cleanest evidence anchors are [Menon 2025](https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1641246/full), which reviewed 26 studies and found promising but heterogeneous evidence, and [Mori 2009](https://pubmed.ncbi.nlm.nih.gov/18844328/), which used 3 g per day for 16 weeks in mild cognitive impairment. [Nagano 2010](https://pubmed.ncbi.nlm.nih.gov/20834180/) adds useful context: reported depression and anxiety improvements in a small trial. The practical gap is the same one that shows up across the report: mechanism and early outcomes are more convincing than broad real-world certainty. In practice, Lion's Mane belongs after the basics, works best when the target is specific, and deserves tracking around benefits, side effects, interactions, and cost before it becomes a standing protocol. ✅ Best for: Adults with subjective cognitive decline, early MCI, or aging-related memory complaints who understand the evidence is small but directionally positive. Adults experimenting with sustained focus support where a subtle effect is still useful. Menopausal women with low-grade mood symptoms, based on Nagano 2010. Users recovering from peripheral nerve injury who want adjunctive support while following real medical care. Supplement-literate users who buy verified fruiting body extract or erinacine-standardized mycelium, cycle use, and stop quickly if libido, genital sensation, mood, or emotional range shifts. ❌ Avoid if: You have active anhedonia, sexual dysfunction, emotional blunting, post-finasteride syndrome history, post-SSRI sexual dysfunction history, mushroom allergy, pregnancy, or lactation. Avoid chronic continuous use if you are risk-averse around the r/LionsManeRecovery signal. Be cautious if you use SSRIs, finasteride, anticoagulants, immunosuppressants, or any drug with overlapping sexual, mood, platelet, or immune effects. Do not use Lion's Mane as a substitute for dementia evaluation, depression treatment, sleep-disorder care, concussion care, or clinician-guided nerve-injury rehabilitation.
Read the full BioHarmony report
My score and my verdict: one signal of three, never the whole answer.
Momentum
Signals begin with Edition 2
Direction needs two weekly snapshots to compare, so the arrows stay off until the next edition. Attention tracking is already running.
Momentum = how fast attention is rising across search, Reddit, PubMed, podcasts, and curated industry newsletters this week; it can flag an item as Overhyped/Fading, but it never overrides the evidence behind Proven. How momentum works.
- Ring
- Proven
- Trend
- Begins with Edition 2
- Momentum
- 21.1%
- BioHarmony Score
- 7.2/10
- Last Updated
- Jul 2, 2026
Sources
- BioHarmony score
- Search trend delta
- Reddit velocity
- PubMed publication count
- Podcast mention frequency
- Curated newsletter mentions
The score anchors the ring; the other five drive momentum, which can nudge the ring by one step at most. How placement works.
Weigh In
Your input feeds the community signal shown beside my verdict. It informs the board and it never sets the score by itself. How community input works.
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