NAC vs Glutathione: Which Is Better for Your Liver?
NAC scores 8.0 and glutathione 6.2, and that gap is real. NAC is the cheaper upstream precursor with a six-decade clinical record, so start there. Glutathione earns its…
- NAC
- Glutathione
Best Interventions for Heavy Metal Detox, Ranked by Evidence
Every intervention Outliyr has scored for heavy metal detox, ranked by its BioHarmony score for this use case rather than its overall rating. The number beside each name is how well that one thing works for heavy metal detox; the tier beside it is what it is worth once safety, cost and effort are counted across everything else.
16 of 74 evaluated interventions score 3.0+ out of 10 for heavy metal detox · 3 comparisons
Ranked for Heavy Metal Detox
Category
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Infrared Sauna
The heavy-metal-detox case for Infrared Sauna is 7.0/10 because Hamaya 2025 gives the most relevant evidence anchor. The existing rationale points to this narrower claim: this verified source measured toxic elements in…
Read the Infrared Sauna report → -
Glycine
Glycine heavy metal detox earns 5.5/10 because Soh 2024 anchors the most relevant signal. Glycine fits heavy metal detox because glycine participates in sleep signaling, glutathione, collagen, methylation, and nervous-system balance, depending…
Read the Glycine report → -
Chlorella
Heavy-metal and toxin burden earns 5.5/10, an interesting but narrow case. The strongest human evidence is Nakano 2007, where 6 g/day of chlorella in pregnant women lowered breast-milk dioxin toxic-equivalents significantly (P=0.003)…
Read the Chlorella report → -
Semaglutide
Heavy-metal-detox is 5.0/10 because Semaglutide has no controlled evidence for clearing mercury, lead, cadmium, or other metals. Moiz 2024 supports fat loss, and fat loss can theoretically mobilize stored compounds, but mobilization…
Read the Semaglutide report → -
Essential Amino Acids
No direct heavy-metal detoxification evidence was verified for EAA supplementation. This use case remains unsupported.
Read the Essential Amino Acids report → -
Ca-AKG (Calcium Alpha-Ketoglutarate)
No direct evidence for heavy-metal clearance, chelation, or clinical detoxification. Use established detoxification protocols instead.
Read the Ca-AKG (Calcium Alpha-Ketoglutarate) report → -
Whole-Body Vibration
No direct heavy-metal detoxification evidence. Whole-body vibration is a mechanical training stimulus, not a chelation or elimination protocol.
Read the Whole-Body Vibration report → -
Metformin
No direct heavy-metal detox evidence exists. Metformin is not a chelator or detoxification protocol.
Read the Metformin report → -
Rapamycin
INSUFFICIENT_EVIDENCE for heavy-metal detoxification and no credible mechanism supports a detox claim.
Read the Rapamycin report → -
Traditional Sauna (Finnish Dry-Heat)
Heavy-metal excretion scores 3.5/10. Sweat does contain trace heavy metals, and sauna increases sweating, but the quantities excreted are small relative to renal clearance and there is no outcome evidence that sauna…
Read the Traditional Sauna (Finnish Dry-Heat) report → -
Zone 2 Cardio
Sweating can eliminate trace amounts of some compounds, but Zone 2 is not a heavy-metal detox protocol. Evidence-based detoxification requires exposure removal, testing, and medical treatment when indicated.
Read the Zone 2 Cardio report → -
NAC (N-Acetylcysteine)
NAC binds some metals and supports glutathione-mediated clearance, but it is not a frontline chelator and dedicated human heavy-metal outcome trials are limited.
Read the NAC (N-Acetylcysteine) report → -
Shilajit
Fulvic acid has chelating properties, but shilajit itself can carry heavy metals when unpurified. Do not use it as a heavy-metal detox protocol.
Read the Shilajit report → -
Spirulina
Often marketed for detox, but human chelation evidence is weak. The bigger issue is that uncertified spirulina can itself carry heavy metals, so the detox framing is the opposite of reassuring.
Read the Spirulina report → -
GlyNAC (Glycine + N-Acetylcysteine)
Glutathione conjugates some toxins via Phase II enzymes and NAC is used in some metal-chelation contexts, but there is no GlyNAC clinical detox outcome. Scores 3.0/10.
Read the GlyNAC (Glycine + N-Acetylcysteine) report → -
Glutathione (GSH)
Glutathione conjugates some toxins via Phase II enzymes, but there is no clinical chelation outcome evidence, so it scores 3.0/10 on mechanism alone.
Read the Glutathione (GSH) report →
Nothing matches those filters.
Comparisons that judge heavy metal detox
Head-to-head reports and category rankings that name a winner on this use case.
Spirulina vs Chlorella: Which Is Better for Detox?
Spirulina scores 7.0 and chlorella 6.5, so spirulina is the better default for most people. It leads on blood pressure, blood sugar, inflammation and breathing. Chlorella leads on…
- Spirulina
- Chlorella
Traditional Sauna vs Infrared Sauna: Which Should You Buy?
Traditional sauna scores 7.7 and infrared 7.4. Infrared actually scores higher on 20 of the 23 use cases both are rated on. Buy traditional anyway if hard outcomes…
- Traditional Sauna
- Infrared Sauna
Questions about heavy metal detox
What scores highest for heavy metal detox?
Infrared Sauna, at 7.0 out of 10 for heavy metal detox. The heavy-metal-detox case for Infrared Sauna is 7.0/10 because Hamaya 2025 gives the most relevant evidence anchor.
What is the cheapest thing that works for heavy metal detox?
Of the top-scoring options, Glycine is the least expensive at about $2 a month, scoring 5.5 out of 10 for heavy metal detox.
How many interventions has Outliyr scored for heavy metal detox?
16 of the 74 interventions evaluated for heavy metal detox score 3.0 out of 10 or better, which is the cut-off for appearing on this page.
