TUDCA vs NAC: Which Is Better for Your Liver?
Different liver problems. NAC scores 8.0–8.5/10 and TUDCA 6.5–7.0/10, and NAC wins liver detox 8.0–8.5/10 against 6.5–7.0/10, but its liver evidence is toxin and oxidative damage. TUDCA owns…
- TUDCA
- NAC
Best Interventions for Addiction Recovery, Ranked by Evidence
Every intervention Outliyr has scored for addiction recovery, ranked by its BioHarmony score for this use case rather than its overall rating. The number beside each name is how well that one thing works for addiction recovery; the tier beside it is what it is worth once safety, cost and effort are counted across everything else.
8 of 46 evaluated interventions score 3.0+ out of 10 for addiction recovery · 1 comparison
Ranked for Addiction Recovery
Category
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NAC (N-Acetylcysteine)
NAC modulates glutamate through the cystine-glutamate antiporter, which is plausibly anti-craving. Gray 2012 found cannabis-dependent adolescents on NAC had 2.4 times the odds of cannabis-negative urine tests (n=116), but the adult replication…
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Tirzepatide
GLP 1 class interest in alcohol and reward pathways is real. Tirzepatide specific substance use RCT evidence is insufficient. Appetite and reward changes may reduce alcohol craving in anecdotes or observational signals.…
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Rapamycin
INSUFFICIENT_EVIDENCE for substance-use disorder treatment or harm reduction.
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Full-Spectrum Hemp (CBD)
Early human signals for cannabis and tobacco craving reduction exist but are small and preliminary; not established.
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Kava (Piper methysticum)
Sometimes used as a non-addictive alternative to alcohol or benzodiazepines for relaxation, and it lacks a withdrawal syndrome, but it has no validated role in addiction treatment and must never be combined…
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Bromantane (Ladasten)
Often discussed in the context of the dopamine-biosynthesis mechanism for post-substance fatigue and apathy, but no published human addiction-recovery RCT for Bromantane exists. Treat as speculative.
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DSIP (Delta Sleep-Inducing Peptide)
This is the most interesting human signal: two uncontrolled 1980s Swiss series reported rapid relief of alcohol and opioid withdrawal symptoms, per Dick 1983 and Dick 1984. The response rates are open-label…
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GLP-1 Receptor Agonists
There is genuine and growing signal that GLP-1 receptor agonists blunt reward-driven consumption of alcohol and other substances, with trials underway, but no approved indication and no confirmed effect size yet. Promising,…
Nothing matches those filters.
What each one costs
Monthly out-of-pocket cost at the most accessible legitimate channel, at the dose the score was given for. 4 of 8 are not priced yet; those cells are left blank rather than guessed.
| Intervention | Monthly cost | At dose | How you get it |
|---|---|---|---|
| NAC (N-Acetylcysteine) | $5–$15 | 600 to 1,200 mg/day | Over the counter |
| Tirzepatide | $299–$449 | 2.5 to 5 to 7.5 to 10 to 12.5 to 15 mg | Prescription |
| Rapamycin | $15–$50 | 3 mg | Prescription |
| Full-Spectrum Hemp (CBD) | Not priced yet | ||
| Kava (Piper methysticum) | Not priced yet | ||
| Bromantane (Ladasten) | $12–$30 | 30 mg | Grey market |
| DSIP (Delta Sleep-Inducing Peptide) | Not priced yet | ||
| GLP-1 Receptor Agonists | Not priced yet |
Comparisons that judge addiction recovery
Head-to-head reports and category rankings that name a winner on this use case.
Questions about addiction recovery
What scores highest for addiction recovery?
NAC (N-Acetylcysteine), at 6.5–7.0 out of 10 for addiction recovery. NAC modulates glutamate through the cystine-glutamate antiporter, which is plausibly anti-craving.
What is the cheapest thing that works for addiction recovery?
Of the top-scoring options, NAC (N-Acetylcysteine) is the least expensive at about $5 a month, scoring 6.5–7.0 out of 10 for addiction recovery.
How many interventions has Outliyr scored for addiction recovery?
8 of the 46 interventions evaluated for addiction recovery score 3.0 out of 10 or better, which is the cut-off for appearing on this page.
