Inside The Revolutionary Epigenetic Cellular Health Test | Ryan Smith @TruDiagnostic
Standard blood tests barely scratch the surface.
Ryan Smith shares how TruDiagnostic’s True Age & True Health tests use over 1,700 biomarkers from just a drop of blood to measure biological age, hormone health, immunity & more. Go beyond standard labs & start bioharmonizing with cutting-edge precision so you can make decisions that actually impact how you feel & age.
📕 Video chapters
0:00 Introduction
3:29 What is biological aging?
6:20 Impact of interventions: lithium, hyperbaric therapies, plasma apheresis
8:39 Evaluating accuracy & reliability of biological age services
10:12 Types of biological age clocks & their strengths
12:23 Live review of Nick’s SYMPHONYAge report
15:10 Interpretation of blood labs vs. methylation proxies
19:45 What are epigenetic biomarker proxies (EBPs)
23:13 Comparing methylation averages to blood labs & implications
27:28 Precision & repeatability of methylation vs. traditional labs
30:12 Importance of immune system in aging & disease
32:48 Can methylation alone capture biological age
35:27 Introduction to the TruHealth report
47:27 Mitochondrial health & ergothioneine
50:07 Future updates & customizing reports
51:39 Identifying drug use via methylation proxies
55:16 NMN vs. NR for NAD+ via methylation data
58:52 TruAge vs. TruHealth: which to choose & why
1:00:45 Outro
🔗 Links
- Full episode show notes: https://outliyr.com/221
📝 Frequently updated articles:
TruDiagnostic TruAge Review: The Top Test to Quantify Your Biological Age & Longevity?
https://outliyr.com/trudiagnostic-truage-review
TruDiagnostic TruHealth Review 2025: 62% Better Than Blood Lab Tests?
https://outliyr.com/ergothioneine-supplement-benefits-uses-review
🛒 Click the link below and use code URBAN to save 10%:
TruDiagnostic Blood Tests:
https://outliyr.com/trudiagnostic
📝 About our guest
Ryan Smith studied Biochemistry at Transylvania University before founding Tailor Made Compounding, which became one of the fastest-growing healthcare companies in the U.S. After exiting in 2020, he launched several ventures, including TruDiagnostic, a CLIA-certified lab specializing in methylation-based diagnostics for longevity & preventive health.
TruDiagnostic leads the field with one of the largest private epigenetic databases, over 13,000 patients, & active participation in 30+ clinical research studies. Ryan remains a key figure in advancing functional medicine through innovative health data solutions.
🔑 Key takeaways
- Biological age gives a clearer picture of health risk than birthdate by showing how your body is actually aging
- Lifestyle basics like exercise, clean eating, stress reduction & social connection remain top tools for aging well
- Some biological age tests are more reliable thanks to stronger prediction power & actionable results
- Longevity interventions can now be ranked using technology that tracks measurable improvements over time
- Leading tests don’t just score your age but give clear next steps to improve healthspan & lifespan
- DNA methylation data offers biomarker proxies that sometimes outperform traditional blood tests