Every intervention Outliyr has scored for social bonding, ranked by its BioHarmony score for this use case rather than its overall rating. The number beside each name is how well that one thing works for social bonding; the tier beside it is what it is worth once safety, cost and effort are counted across everything else.
17 of 84 evaluated interventions score 3.0+ out of 10 for social bonding · 3 comparisons
Xu 2024 reports 28 RCTs, 3,461 patients; erectile-function scores improved without statistically significant intermediate-term prostate or urinary worsening. Bhasin 1996 points in the same direction, but route, dose, baseline status, and outcome…
Semaglutide can change food-centered behavior without reliably improving or harming relationships. Wilding 2021 supports appetite and weight effects, which can reduce food noise and shame for some users. It can also make…
Group rides, run clubs, hikes, and walking partners can turn Zone 2 into a social habit. The score is modest because many common Zone 2 formats, especially indoor trainer sessions, are solitary…
Not a relevant EAA use case. No social bonding evidence was verified.
Not applicable as a primary intervention. Group rehab could add social contact, but that is not inherent to whole-body vibration.
Not applicable. Metformin is not a social-bonding intervention.
Not applicable. No oxytocin, social behavior, or affiliative-behavior evidence.
Lower social anxiety can ease conversation and connection, and kava is drunk socially across the Pacific, but there is no direct social-bonding trial. Indirect anxiolytic effect only.
Social bonding is oxytocin's signature claim and its most defensible one, but the evidence is mixed rather than settled. The cleanest human chain runs from a couple-conflict study where a single intranasal…
Coherence state associated with prosocial emotions in HeartMath lab work.
Group HIIT classes can create community. Solo treadmill or bike 4x4 has little inherent social component.
Indirect via social-anxiety reduction; no direct social-bonding evidence.
Social-bonding support is indirect through mood and anxiety improvements; no social-connection endpoint has been tested.
Reducing social threat response may help some anxious users, but Selank has no social-bonding endpoint.
Mood, libido, and confidence can alter social behavior, but no social-bonding evidence exists. This remains anecdotal and indirect.
Nothing matches those filters.
Monthly out-of-pocket cost at the most accessible legitimate channel, at the dose the score was given for. 5 of 17 are not priced yet; those cells are left blank rather than guessed.
| Intervention | Monthly cost | At dose | How you get it |
|---|---|---|---|
| TRT (Testosterone Replacement Therapy) | $50–$300 | Clinician-selected formulation at the lowest dose likely to restore physiologic testosterone | Prescription |
| Semaglutide | $199–$349 | 0.25 mg weeks 1 to 4, 0.5 mg weeks 5 to 8, 1.0 mg weeks 9 to 12, 1.7 mg weeks 13 to 16, 2.4 mg week 17 onward | Prescription |
| Zone 2 Cardio | Not priced yet | Over the counter | |
| Rapamycin | $15–$50 | 3 mg | Prescription |
| Essential Amino Acids | Not priced yet | ||
| Glycine | $2–$3 | 3 g oral glycine | Over the counter |
| Whole-Body Vibration | $50–$100 | 30 Hz, roughly 0.3g, 10-20 min standing | Over the counter |
| Metformin | $4–$30 | 500 mg with dinner for 1 week, then 500 mg twice daily for 1 week, then increase by 500 mg/week toward 1000 mg twice daily as tolerated | Prescription |
| Ca-AKG (Calcium Alpha-Ketoglutarate) | $15–$30 | 1 g/day generic Ca-AKG oral | Over the counter |
| Kava (Piper methysticum) | Not priced yet | ||
| Oxytocin (Intranasal) | $67–$119 | 24 IU | Prescription |
| HRV Biofeedback | $5 | 20 min/session at individual RF (4.5 to 6.5 bpm) | Over the counter |
| Norwegian 4×4 | Not priced yet | Over the counter | |
| L-Theanine | $3–$8 | 200 mg L-theanine + 100 mg caffeine | Over the counter |
| Saffron | Not priced yet | ||
| Selank | $30–$60 | 0.15% intranasal spray, roughly 1-3 sprays per nostril per day depending on actuation size | Grey market |
| Tongkat Ali | $20–$40 | 200 mg/day Physta standardized extract | Over the counter |
Head-to-head reports and category rankings that name a winner on this use case.
They solve different problems and the scores hide that. Oxytocin scores 6.5–7.0/10 against PT-141's 5.0–5.5/10, mostly on safety and cost. PT-141 still wins libido 5.5/10 against 2.5/10. Oxytocin…
PT-141 scores 5.0–5.5/10 and melanotan II 4.5–5.0/10, and both land in the neutral tier. PT-141 is the defensible one. It targets the brain receptor that drives desire, it…
Pick by symptom. Semax scores 7.0–7.5/10 and wins focus. Selank scores 6.5–7.0/10 and wins anxiety, mood and stress resilience. The 0.2 gap decides nothing. The mechanisms overlap at…
TRT (Testosterone Replacement Therapy), at 5.5–6.0 out of 10 for social bonding. Xu 2024 reports 28 RCTs, 3,461 patients; erectile-function scores improved without statistically significant intermediate-term prostate or urinary worsening.
Of the top-scoring options, Glycine is the least expensive at about $2 a month, scoring 4.0–4.5 out of 10 for social bonding.
17 of the 84 interventions evaluated for social bonding score 3.0 out of 10 or better, which is the cut-off for appearing on this page.
