Peptide Intelligence

Peptides, scored by the evidence

See which peptides the evidence backs, what each is researched for, and its US status.

  • 58BioHarmony scores
  • 95compounds
  • Everyentry sourced

95 compoundsranked by score

  1. 7.5/10BPC-157Strong recommendRecoveryNot FDA approvedBPC-157 is a 15-amino-acid gastric peptide fragment with consistent preclinical repair data, including a 2025 sports-medicine systematic review of 36 studies with 35…
  2. 7.5/10TB-500 (Thymosin Beta-4 Fragment)Strong recommendRecoveryNot FDA approvedTB-500 is a synthetic LKKTETQ fragment marketed for soft-tissue repair, but most human evidence is on full-length topical thymosin beta-4: Sosne 2023 reported corneal…
  3. 7.4/10Thymosin Alpha-1Strong recommendRecoveryNot FDA approvedThymosin Alpha-1 is a 28-amino-acid thymic peptide with strongest evidence in immune-compromised and hospital-adjacent settings: Cao 2024 pooled 39 acute COPD…
  4. 7.2/10GHK-Cu (Copper Peptide)Strong recommendRecoveryNot FDA approvedGHK-Cu is a human copper-binding tripeptide with the best evidence for topical skin repair and wound healing, including Mulder 1994 diabetic ulcer data showing 98.5%…
  5. 7.2/10Thymosin Beta-4 (Full)Strong recommendRecoveryInvestigationalThymosin beta-4 is the native 43-amino-acid peptide that promotes tissue repair via actin-sequestering and the Ac-SDKP repair axis.
  6. 7.1/10KPV (Lysine-Proline-Valine)Strong recommendRecoveryNot FDA approvedKPV is a three-amino-acid alpha-MSH fragment that reduced inflammation in mouse colitis models through PepT1 uptake and NF-kB pathway suppression, but it still has zero…
  7. 7.1/10SemaxStrong recommendRecoveryNot FDA approvedSemax is a Russian-developed ACTH 4-7 + PGP heptapeptide with the strongest human signal in post-stroke recovery, including a 110-patient Gusev et al.
  8. 6.8/10Gonadorelin (GnRH)Worth tryingGH & hormonesFDA-approved product existsGonadorelin is synthetic GnRH, a decapeptide that tells the pituitary to release LH and FSH.
  9. 6.8/10SelankWorth tryingBrain & sleepNot FDA approvedSelank is a synthetic tuftsin-derived heptapeptide studied as a non-sedating anxiolytic.
  10. 6.7/10ARA-290Worth tryingRecoveryInvestigationalARA-290 (cibinetide) is an EPO-derived peptide that activates the innate repair receptor to regrow small nerve fibers without EPO's blood effects.
  11. 6.7/10Epitalon (Epithalon)Worth tryingBrain & sleepNot FDA approvedEpitalon is a synthetic AEDG tetrapeptide with in vitro telomerase and telomere data, animal lifespan signals, and Russian pineal-peptide melatonin studies.
  12. 6.6/10ThymulinWorth tryingLongevityInvestigationalThymulin (zinc-thymulin) is a chemically defined, zinc-dependent thymic nonapeptide hormone with deep classical immunology behind it but no modern human trial of the…
  13. 6.5/10AHK-Cu (Copper Tripeptide)Worth tryingSkin & hairInvestigationalAHK-Cu is a topical copper tripeptide, Alanine-Histidine-Lysine plus copper, marketed for hair growth.
  14. 6.5/10Kisspeptin-10Worth tryingGH & hormonesNot FDA approvedKisspeptin-10 is an investigational reproductive neuropeptide that activates the HPG axis through the KISS1R receptor.
  15. 6.5/10OxytocinWorth tryingFDA-approved product existsIntranasal oxytocin is the endogenous bonding hormone used off-label as a nasal spray for social connection, anxiety, and libido.
  16. 6.4/10PinealonWorth tryingBrain & sleepNot FDA approvedPinealon (Glu-Asp-Arg, or EDR) is a synthetic Khavinson tripeptide marketed for neuroprotection and cognition.
  17. 6.3/10CerebrolysinWorth tryingRecoveryNot FDA approvedCerebrolysin is a porcine brain-derived peptide mixture given by IV or IM infusion.
  18. 6.2/10IpamorelinWorth tryingRecoveryNot FDA approvedIpamorelin is a selective growth-hormone secretagogue with strong receptor selectivity but almost no human efficacy data: its only completed human efficacy trial…
  19. 6.2/10Melanotan IWorth tryingSkin & hairFDA-approved product existsMelanotan I is most defensible for photoprotection in EPP and planned UV exposure, with Langendonk 2015 reporting 69.4 vs 40.8 hours of pain-free sun exposure in the US…
  20. 6.2/10SNAP-8Worth tryingSkin & hairNot FDA approvedSNAP-8 (acetyl octapeptide-3) is a topical cosmetic peptide sold as a Botox alternative.
  21. 6.1/10MOTS-cWorth tryingWeight & metabolicNot FDA approvedMOTS-c is a 16-amino-acid mitochondrial-derived peptide discovered in Lee 2015 that activates AMPK through the folate and purine pathway.
  22. 6.1/10TirzepatideWorth tryingWeight & metabolicFDA-approved product existsTirzepatide is a once-weekly subcutaneous dual GIP plus GLP-1 receptor agonist with unusually large weight-loss and glycemic effects.
  23. 6.0/10DSIP (Delta Sleep Inducing Peptide)Worth tryingRecoveryNot FDA approvedDSIP (Delta Sleep-Inducing Peptide) is a naturally-occurring nonapeptide whose famous name oversells it.
  24. 6.0/10SS-31 (Elamipretide)Worth tryingRecoveryFDA-approved product existsSS-31 (elamipretide) is a mitochondria-targeting tetrapeptide that binds cardiolipin.
  25. 6.0/10TesamorelinWorth tryingWeight & metabolicFDA-approved product existsTesamorelin is a stabilized GHRH analog that reduced visceral adipose tissue in the landmark Falutz 2007 HIV lipodystrophy Phase 3 trial and has newer support for…
  26. 5.9/10Semaglutide (GLP-1 Agonist)Worth tryingWeight & metabolicFDA-approved product existsSemaglutide is a prescription GLP-1 receptor agonist that produced 14.9% mean weight loss in STEP-1 and cut 3-point MACE by 20% in SELECT, but the 5.5-6.0/10 score holds…
  27. 5.9/10SermorelinWorth tryingRecoveryFDA-approved product existsSermorelin (GHRH 1-29) is a short-acting peptide that prompts your own pituitary to release growth hormone, and it is the only one in its class with a former FDA…
  28. 5.9/10ThymalinWorth tryingLongevityNot FDA approvedThymalin is a bovine-thymus peptide extract studied for immune restoration and aging.
  29. 5.8/10CagrilintideWorth tryingWeight & metabolicInvestigationalCagrilintide (AM833) is a long-acting amylin receptor analogue that drove about 11.8 percent weight loss as monotherapy at 68 weeks in REDEFINE 1 per Garvey 2025, with…
  30. 5.8/10CJC-1295 No DAC (Mod GRF 1-29)Worth tryingRecoveryNot FDA approvedCJC-1295 No DAC (Mod GRF 1-29) is a short-acting GHRH peptide, almost always stacked with ipamorelin, that prompts a pulse of your own growth hormone.
  31. 5.8/10OrforglipronWorth tryingWeight & metabolicFDA-approved product existsOrforglipron (Foundayo) is the first FDA-approved non-peptide oral GLP-1 pill, cleared for obesity in April 2026.
  32. 5.8/10VK2735Worth tryingWeight & metabolicInvestigationalVK2735 is an investigational dual GLP-1 and GIP receptor agonist from Viking Therapeutics that produced about 14.7 percent weight loss at 13 weeks in its peer-reviewed…
  33. 5.7/10VilonNeutralLongevityNot FDA approvedVilon is the Lysine-Glutamic acid (KE) dipeptide from Vladimir Khavinson's bioregulator program, sold for immune restoration and anti-aging.
  34. 5.6/10MazdutideNeutralWeight & metabolicNot FDA approvedMazdutide (IBI362) is the first GLP-1 plus glucagon dual agonist approved anywhere, cleared in China for obesity in June 2025.
  35. 5.6/10RetatrutideNeutralWeight & metabolicInvestigationalRetatrutide is Lilly's investigational once-weekly GLP-1/GIP/glucagon triple agonist.
  36. 5.5/10GHRP-2 (Pralmorelin)NeutralRecoveryNot FDA approvedGHRP-2 (pralmorelin) is a ghrelin-receptor peptide that drives a strong growth-hormone pulse, approved in Japan since 2004 as a diagnostic test.
  37. 5.5/10HumaninNeutralWeight & metabolicInvestigationalHumanin is a 24-amino-acid mitochondrial-derived peptide that declines with age and runs much higher in children of centenarians, per Yen 2020, but it scores Neutral…
  38. 5.4/10PT-141 (Bremelanotide)NeutralGH & hormonesFDA-approved product existsPT-141 (bremelanotide) is the only FDA-approved drug for low sexual desire in premenopausal women (Vyleesi, 2019).
  39. 5.4/10VIP (Vasoactive Intestinal Peptide)NeutralImmune & gutNot FDA approvedVIP, or vasoactive intestinal peptide, is the endogenous neuropeptide whose synthetic form is aviptadil, used off-label for anti-inflammatory, immune, respiratory, and…
  40. 5.2/10LiraglutideNeutralWeight & metabolicFDA-approved product existsLiraglutide is a once-daily prescription GLP-1 receptor agonist. In the 3,731-person SCALE trial, 3.0 mg with lifestyle counseling produced 8.4 kg mean weight loss…
  41. 5.1/10CagriSemaNeutralWeight & metabolicInvestigationalCagriSema is an investigational once-weekly amylin plus GLP-1 injectable that produced about 22.7% weight loss on-treatment in REDEFINE 1, per Garvey 2025 in NEJM.
  42. 5.1/10GHRP-6NeutralRecoveryNot FDA approvedGHRP-6 is a synthetic peptide that activates the ghrelin receptor to release a pulse of your own growth hormone.
  43. 5.1/10SurvodutideNeutralWeight & metabolicInvestigationalSurvodutide (BI 456906) is an investigational once-weekly GLP-1 and glucagon dual agonist that drove up to 16.6% weight loss in Phase 3, per the Boehringer Ingelheim…
  44. 5.0/10BAM15NeutralWeight & metabolicInvestigationalBAM15 is an experimental mitochondrial uncoupler that reversed diet-induced obesity and insulin resistance in mice without raising body temperature, the effect that made…
  45. 5.0/10NAD+NeutralNot FDA approvedNAD+ (Direct) is the central redox coenzyme given by IV, injection, sublingual, or intranasal route, and it scores 5.0-5.5/10 because the human evidence is a single…
  46. 5.0/10P21 (P021)NeutralBrain & sleepInvestigationalP21 (P021) is a CNTF-derived peptidomimetic that crosses the blood-brain barrier and, in mice, raises BDNF, lifts hippocampal neurogenesis, and lowers tau pathology in…
  47. 5.0/10TesofensineNeutralWeight & metabolicInvestigationalTesofensine is a small-molecule triple monoamine reuptake inhibitor that produced strong Phase 2 weight loss for obesity, about 9 to 11 percent at 24 weeks per Astrup…
  48. 4.9/105-Amino-1MQNeutralRecoveryInvestigational5-Amino-1MQ is a synthetic NNMT-inhibitor research compound that cut fat mass in obese mice and raised NAD+ in cultured fat cells (Neelakantan 2018), but it has zero…
  49. 4.9/10Ibutamoren (MK-677)NeutralRecoveryNot FDA approvedMK-677 (ibutamoren) is an oral, once-daily growth-hormone secretagogue that raises IGF-1 by about 50 to 97 percent and adds roughly 1.1 kg of fat-free mass, per the Nass…
  50. 4.9/10PE-22-28 (Spadin)NeutralBrain & sleepInvestigationalPE-22-28 is a synthetic spadin analogue that blocks the TREK-1 potassium channel, a target with a clean and well-characterized link to fast-acting antidepressant effects…
  51. 4.7/10LL-37 (Cathelicidin)NeutralRecoveryNot FDA approvedLL-37 (Cathelicidin) is the only human cathelicidin antimicrobial peptide, with a rich antimicrobial and wound-healing mechanism but thin human therapy data: one small…
  52. 4.7/10Pentosan Polysulfate (PPS)NeutralRecoveryFDA-approved product existsPentosan polysulfate (oral Elmiron) is an FDA-approved sulfated polysaccharide drug for interstitial cystitis bladder pain, sometimes used off-label for joints.
  53. 4.7/10SLU-PP-332NeutralWeight & metabolicInvestigationalSLU-PP-332 is a synthetic pan-ERR agonist developed in the Thomas Burris lab. Billon et al.
  54. 4.5/10Melanotan IINeutralWeight & metabolicNot FDA approvedMelanotan II is a fast tanning and sexual-response peptide with a harsher safety tradeoff; Nelson 2012 reported rhabdomyolysis after a 6 mg injection.
  55. 4.4/10CJC-1295 DACCautionRecoveryNot FDA approvedCJC-1295 with DAC is the long-acting form, dosed about weekly, that keeps growth hormone elevated for 6 to 8 days.
  56. 4.4/10DihexaCautionBrain & sleepNot FDA approvedDihexa is a gray-market angiotensin IV analog with rodent synaptogenesis and memory data, including McCoy 2013 and Sun 2021, but zero human trials, no human…
  57. 4.1/10FOX04-DRICautionLongevityInvestigationalFOXO4-DRI is a designed senolytic peptide that kills senescent cells by breaking the FOXO4 to p53 bond, famous for restoring fur and kidney function in aged mice per…
  58. 3.0/10AOD-9604CautionRecoveryNot FDA approvedAOD-9604 is a human growth hormone fragment (hGH 176 to 191) marketed for fat loss, but its only controlled human weight-loss program failed to beat placebo, per the…
  59. Not yet scoredAbaloparatide (Tymlos)RecoveryFDA-approved product exists
  60. Not yet scoredATX-304 (O-304)Weight & metabolicInvestigational
  61. Not yet scoredB7-33LongevityInvestigationalB7-33 is a preclinical single-chain relaxin-family peptide agonist studied for selective antifibrotic signaling in animal models.
  62. Not yet scoredBerobenatide (MET-097i / PF-08653944)Weight & metabolicInvestigational
  63. Not yet scoredCalcitonin SalmonRecoveryFDA-approved product exists
  64. Not yet scoredDesmopressinGH & hormonesFDA-approved product exists
  65. Not yet scoredDulaglutide (Trulicity)Weight & metabolicFDA-approved product exists
  66. Not yet scoredEnicepatide (CT-388)Weight & metabolicInvestigational
  67. Not yet scoredExenatideWeight & metabolicFDA-approved product exists
  68. Not yet scoredGlucagonWeight & metabolicFDA-approved product exists
  69. Not yet scoredGoserelin (Zoladex)GH & hormonesFDA-approved product exists
  70. Not yet scoredHistrelin (Supprelin LA)GH & hormonesFDA-approved product exists
  71. Not yet scoredIcatibant (Firazyr)Immune & gutFDA-approved product exists
  72. Not yet scoredLanreotideGH & hormonesFDA-approved product exists
  73. Not yet scoredLeuprolideGH & hormonesFDA-approved product exists
  74. Not yet scoredLinaclotide (Linzess)Immune & gutFDA-approved product exists
  75. Not yet scoredLixisenatideWeight & metabolicFDA-approved product exists
  76. Not yet scoredMaridebart Cafraglutide (MariTide)Weight & metabolicInvestigational
  77. Not yet scoredNavepegritide (Yuviwel)GH & hormonesFDA-approved product exists
  78. Not yet scoredOctreotideGH & hormonesFDA-approved product exists
  79. Not yet scoredP110Brain & sleepInvestigationalP110 is a preclinical peptide inhibitor of the stress-associated Drp1-Fis1 interaction. Recent animal and cell studies do not establish human safety or effectiveness.
  80. Not yet scoredPasireotide (Signifor)GH & hormonesFDA-approved product exists
  81. Not yet scoredPEG-MGFRecoveryNot FDA approved
  82. Not yet scoredPemvidutideWeight & metabolicInvestigational
  83. Not yet scoredPetrelintideWeight & metabolicInvestigational
  84. Not yet scoredPlecanatide (Trulance)Immune & gutFDA-approved product exists
  85. Not yet scoredPramlintide (SymlinPen)Weight & metabolicFDA-approved product exists
  86. Not yet scoredRusfertide (PTG-300)Investigational
  87. Not yet scoredSetmelanotide (Imcivree)Weight & metabolicFDA-approved product exists
  88. Not yet scoredTeduglutide (Gattex)Immune & gutFDA-approved product exists
  89. Not yet scoredTeriparatideRecoveryFDA-approved product exists
  90. Not yet scoredTerlipressin (Terlivaz)FDA-approved product exists
  91. Not yet scoredTriptorelin (Trelstar)GH & hormonesFDA-approved product exists
  92. Not yet scoredUBT251Weight & metabolicInvestigational
  93. Not yet scoredVosoritide (Voxzogo)GH & hormonesFDA-approved product exists
  94. Not yet scoredZenagamtide (Amycretin)Weight & metabolicInvestigational
  95. Not yet scoredZiconotide (Prialt)FDA-approved product exists

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