Renue Shield
Renue by Science
$69.95
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URBAN for an exclusive discount Verified June 2026The current successor to the NAD Defender formula Nick highlighted for active users, Shield now combines liposomal vitamin C, CaAKG, PEA, and hyaluronic acid in a two-capsule serving.
Pros
- The current formula combines four complementary compounds in one liposomal blend
- Provides 60 servings with published third-party testing
- Nick highlighted the earlier NAD Defender formula as an appealing all-in-one option for active users
Cons
- The current Shield formula differs substantially from the NAD Defender formula Nick originally reviewed
- The current formula no longer contains berberine
- Requires two capsules per serving
Best For
- You want a multi-ingredient longevity blend
- You prefer a liposomal capsule formula
- You want CaAKG alongside vitamin C, PEA, and hyaluronic acid
Skip If
- You want the original NAD Defender formula
- You specifically want berberine in the blend
- You prefer a single-ingredient CaAKG product
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