Finding the best biohacking supplements is overwhelming. Thousands of brands make bold claims, yet most use cheap fillers, underdosed ingredients, or proprietary blends that hide what you are actually getting. I have spent years testing health optimization supplements firsthand — tracking biomarkers, monitoring subjective effects, and comparing formulations — so you do not have to wade through the noise.
This collection features my top-rated supplements for cognitive performance, energy, recovery, longevity, and overall vitality. Every product here meets strict criteria: third-party testing, bioavailable forms, transparent labeling, and ingredients backed by peer-reviewed research. From nootropic supplements that sharpen focus to adaptogens that build resilience, these are the formulations I actually use and recommend as a Certified Personal Trainer who works with high performers.
Many of these brands offer exclusive Outliyr discount codes, saving you anywhere from 10 to 20 percent off retail. Browse the full lineup below to find the right supplement stack for your goals.
Supplements Comparison
| Product | Best For | Price | Discount | Rating | |
|---|---|---|---|---|---|
| 5-Amino-1MQ | a cutting-edge compound targeting fat metabolism and cellular energy | URBAN14.8% off | ★★★½☆ | Get Deal | |
| 9-Me-BC | potent dopaminergic support for motivation and focus | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Ease Magnesium | You experience muscle cramps, soreness, or tension and want targeted relief | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Oceans Alive | Activation Products' flagship phytoplankton blend | URBAN15% off | ★★★½☆ | Get Deal | |
| Adapt Naturals Bio-Avail Colostrum+ | Readers wanting colostrum plus added lactoferrin and beta-glucan | — | — | — | Get Best Price |
| Amino Co EAAs | to support muscle recovery and protein synthesis | URBAN30.7% off | ★★★★☆ | Get Deal | |
| ARMRA Colostrum Health Revival | Readers who want the most established consumer colostrum brand | — | — | Get Best Price | |
| ARMRA Colostrum Performance Revival | Athletes seeking colostrum plus workout-recovery ingredients | — | — | Get Best Price | |
| Auro Wellness Glutaryl | Readers who prefer a topical glutathione spray | URBAN10% off | — | Get Deal | |
| AX3 Bio-Pure Astaxanthin | Anyone wanting a research-backed astaxanthin with proven bioavailability, esp… | URBAN20% off | ★★★★☆ | Get Deal | |
| BIOptimizers Berberine Breakthrough | Nick’s top overall berberine formula | URBAN10% off | ★★★½☆ | Get Deal | |
| BiOptimizers Magnesium Breakthrough | comprehensive magnesium support from multiple forms | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers MassZymes | You experience bloating, gas, or discomfort after meals | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers Probiotic Breakthrough (formerly P3-OM) | — | URBAN10% off | ★★★★½ | Get Deal | |
| Black Lotus Shilajit | a mineral-rich daily supplement with fulvic acid | URBAN15% off | ★★★★☆ | Get Deal | |
| Bloom Nutrition Colostrum + Collagen | Readers prioritizing convenience over specialized full-dose products | — | — | — | Get Best Price |
| Blue Cannatine | targeted nutritional support for your specific health goals | URBAN10% off | ★★★★☆ | Get Deal | |
| Blue Sky Peptides | Budget buyers who prioritize low prices and frequent deals, and are comfortab… | $39.95 | — | ★★½☆☆ | Get Best Price |
| BodyBio E-Lyte | high-potassium electrolytes | URBAN15% off | ★★★★☆ | Get Deal | |
| BodyBio Liposomal Glutathione | a premium liposomal glutathione from a trusted brand | URBAN15.5% off | — | Get Deal | |
| Botanabolic | multi-mechanism testosterone optimization with botanical androgens | URBAN14.8% off | ★★★★☆ | Get Deal | |
| C8 MCT Oil | targeted nutritional support for your specific health goals | URBAN27.8% off | ★★★★☆ | Get Deal | |
| Chemyo | SARMs researchers who prioritize verified purity, transparent testing, and a … | $59.99 | — | — | Get Best Price |
| Codeage Liposomal Urolithin A | Readers seeking a multi-ingredient Urolithin A formula with added mitochondri… | URBAN10% off | — | Get Deal | |
| CollaGenius | cognitive support combined with beauty and anti-aging benefits | URBAN7.6% off | ★★★½☆ | Get Deal | |
| Core Peptides | Researchers who value fast shipping and custom blend options, but proceed wit… | $47 | — | ★★★★☆ | Get Best Price |
| Cortisol Balance | targeted cortisol management with clinically studied ingredients | $60 | — | ★★★★☆ | Get Best Price |
| Cosmic Nootropic | International readers seeking rare pharmaceutical nootropics | URBAN55% off | — | Get Deal | |
| Cowboy Colostrum Nature's Gold | Readers wanting a straightforward first-milking colostrum with flavor options | — | — | — | Get Best Price |
| Crevolution | creatine, GAA and TMG in one unflavored scoop | URBAN15% off | — | Get Deal | |
| D3K2 ReSet | D3 and K2 in proper ratio from a trusted brand | URBAN10% off | — | Get Deal | |
| Do Not Age Spermidine | Longevity enthusiasts who want to support autophagy and cellular renewal thro… | $39 | — | ★★★½☆ | Get Best Price |
| DoNotAge Pure NR | International buyers seeking a high-dose bulk NR capsule | — | — | — | Get Best Price |
| Double Wood Berberine | an affordable 500 mg berberine HCl capsule | $19.95 | — | ★★★★☆ | Get Best Price |
| Double Wood Resveratrol | Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol … | $19.95 | — | ★★★½☆ | Get Best Price |
| Double Wood Spermidine | Those who want a high-dose pure spermidine supplement at a competitive price … | $39.95 | — | ★★★★☆ | Get Best Price |
| Dream Optimizer | Readers who want a fast, convenient spray for occasional nighttime wakeups | URBAN15% off | — | Get Deal | |
| Earth Circle Organics Chlorella | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina + Chlorella | a whole-food plant-based source of vitamins, minerals, and protein | NICKURBAN20% off | ★★★★☆ | Get Deal | |
| Ergothioneine | targeted nutritional support for your specific health goals | — | ★★★½☆ | Get Best Price | |
| Essential C Complex | — | — | — | Get Best Price | |
| Folqs First-Day Milking Bovine Colostrum | to strengthen your gut lining and immune defenses naturally | URBAN10% off | ★★★★☆ | Get Deal | |
| Healthgevity bioREPAIR | Readers wanting a targeted capsule formula for gut-barrier support | URBAN10% off | — | Get Deal | |
| Healthgevity IGNITE+ | metabolic support for glucose regulation and body composition | URBAN10% off | ★★★½☆ | Get Deal | |
| Healthgevity Rejuvenate 2.0 | Serious longevity enthusiasts who want a comprehensive multi-pathway senolyti… | $124.99 | — | ★★★★½ | Get Best Price |
| Hergevity Balance | hormone support through estrogen receptor-beta signaling without direct hormo… | URBAN9.3% off | ★★★★☆ | Get Deal | |
| HighStreetPharma | Readers who already have appropriate medical guidance and seek established ge… | $30 | — | — | Get Best Price |
| InfiniFiber | broad prebiotic fiber diversity plus a probiotic in a single scoop | $54.99 | — | ★★★★½ | Get Best Price |
| Infiniwell Senolytic | Budget-conscious biohackers wanting a proven senolytic formula without premiu… | $69.95 | — | ★★★★☆ | Get Best Price |
Showing 24 of 140 products in Supplements
Editors ChoiceReMyte
RnA ReSet
- Best for
- You want the most absorbable mineral supplementation available
- Skip if
- You already take a comprehensive mineral supplement you trust
Details checked 01/20/2026
URBAN — 10% off
Ultimate (Ionic) Minerals
RnA ReSet
- Best for
- You want the most absorbable mineral supplementation available
- Skip if
- You already take a comprehensive mineral supplement you trust
Details checked 11/22/2025
URBAN — 10% off
AX3 Bio-Pure Astaxanthin
AX3
- Best for
- Anyone wanting a research-backed astaxanthin with proven bioavailability, especially athletes and those focused on recovery and skin health
- Skip if
- You're on a tight budget or prefer non-subscription supplements
URBAN — 20% off
InfiniFiber
Nootropics Depot
- Best for
- You want broad prebiotic fiber diversity plus a probiotic in a single scoop
- Skip if
- You already do well on a simple single-source fiber like psyllium
Details checked 05/17/2026
$54.99
Get Best Price
BiOptimizers Probiotic Breakthrough (formerly P3-OM)
BiOptimizers
- Skip if
- You want a multi-strain probiotic to broadly diversify or recolonize your microbiome.
Details checked 08/22/2026
URBAN — 10% off
Healthgevity Rejuvenate 2.0
Healthgevity
- Best for
- Serious longevity enthusiasts who want a comprehensive multi-pathway senolytic with branded clinically studied ingredients
- Skip if
- You prefer simple single-ingredient senolytics or are on a tight supplement budget
$124.99
Get Best Price
NOVOS Core
NOVOS
- Best for
- You want the most scientifically validated longevity supplement
- Skip if
- You dislike powder supplements or prefer capsules
Details checked 06/08/2026
URBAN5 — $5 off
Editors ChoicePaleovalley Electrolytes
Paleovalley
- Best for
- You're active and sweat frequently during workouts
- Skip if
- You already eat a mineral-rich whole food diet and stay well-hydrated
Details checked 03/29/2026
Qualia Scientific Formulas
Qualia (Neurohacker)
- Best for
- You want a comprehensive, multi-pathway nootropic stack
- Skip if
- You prefer building your own custom supplement stack
Details checked 11/17/2025
URBAN — 15% off
Peptidology Peptides
Peptidology
- Best for
- US-based researchers who prioritize verified purity above all else and want the most rigorous testing standards.
- Skip if
- You're outside the US or prefer non-injectable forms.
URBAN — 15% off
Qualia Senolytic
Qualia (Neurohacker)
- Best for
- Those who want a clinically tested senolytic with published human trial data on their own product
- Skip if
- You prefer daily supplements over a 2-day monthly protocol
Details checked 03/29/2026
$69
Get Best Price
Perpetua.Life AEON
Perpetua.Life
- Best for
- You want a comprehensive all-in-one longevity supplement
- Skip if
- You prefer individual ingredient dosing control
Details checked 11/14/2025
URBAN2 — 10.2% off
LVLUP Oral Peptides (& More)
LVLUP Health
- Best for
- People who want peptide benefits without injections, especially BPC-157 and TB-500 in oral form.
- Skip if
- You specifically need injectable peptides or need fast domestic US shipping.
Details checked 11/26/2025
URBAN — 23.5% off
Omega-3 Complex
Paleovalley
- Best for
- You want a whole-food omega-3 source in its natural phospholipid form
- Skip if
- You're vegetarian or vegan
Details checked 09/18/2026
Peptide Bioregulators
Profound Health
- Best for
- You're interested in targeted organ-specific anti-aging support
- Skip if
- You want fast, noticeable results (bioregulators work gradually)
Details checked 11/16/2025
URBAN — 15% off
KetoneAid KE4
KetoneAid
- Best for
- You want the strongest exogenous ketone supplement available
- Skip if
- You're on a tight budget (premium ketone esters are expensive)
Details checked 03/29/2026
$89.95
OUTLIYR — Free shipping off
Raw Power Superfoods
Raw Power Superfoods
- Best for
- You want nutrient-dense whole food powders for smoothies and meals
- Skip if
- You prefer eating whole fruits and vegetables over powders
Details checked 11/01/2025
$32.95
Get Best Price
Nootropics Depot
Nootropics Depot
- Best for
- You want to enhance focus, memory, or mental clarity
- Skip if
- You haven't optimized sleep and nutrition first (start there)
Details checked 11/06/2025
$24.97
View Product
Blue Cannatine
Troscriptions
- Best for
- You want targeted nutritional support for your specific health goals
- Skip if
- You haven't optimized diet, sleep, and exercise first (they matter more)
Details checked 11/06/2025
URBAN — 10% off
Real Mushrooms Adaptogenic Mushrooms
Real Mushrooms
- Best for
- You want adaptogenic support for immunity, energy, and cognition
- Skip if
- You're allergic to fungi or mold-sensitive
Details checked 11/16/2025
URBAN — 10% off
Cortisol Balance
Transparent Labs
- Best for
- You want targeted cortisol management with clinically studied ingredients
- Skip if
- You're already managing cortisol well through lifestyle factors
Details checked 02/10/2026
$60
Get Best Price
Hergevity Balance
Healthgevity
- Best for
- You want hormone support through estrogen receptor-beta signaling without direct hormone supplementation
- Skip if
- You're male or not concerned with estrogen balance
Details checked 06/13/2026
URBAN — 9.3% off
Botanabolic
LVLUP Health
- Best for
- You want multi-mechanism testosterone optimization with botanical androgens
- Skip if
- You're already on TRT or hormone therapy
Details checked 02/10/2026
URBAN — 14.8% off
NeuroEffect
Paleovalley
- Best for
- You want a comprehensive mushroom nootropic with 8 organic species
- Skip if
- You already take a dedicated mushroom supplement blend
Details checked 02/10/2026
