Every intervention Outliyr has scored for strength and power, ranked by its BioHarmony score for this use case rather than its overall rating. The number beside each name is how well that one thing works for strength and power; the tier beside it is what it is worth once safety, cost and effort are counted across everything else.
41 of 101 evaluated interventions score 3.0+ out of 10 for strength and power · 6 comparisons
Lanhers 2015 reports Lower-limb global SMD 0.235 (small-to-moderate). Chilibeck 2017 points in the same direction, but route, dose, baseline status, and outcome tracking decide whether Creatine Monohydrate matters for this use case.…
Hagiyama 2024 reports 12 RCTs; 622 patients; low-certainty improvement in patient-reported outcomes and very-low-certainty strength signal after lower-limb surgeries. Wittholz 2024 points in the same direction, but route, dose, baseline status, and…
Bhasin 1996 reports Classic androgen dose-response trial; supports anabolic mechanism but used supraphysiologic dosing in normal men, not standard TRT. The score stays conditional because TRT (Testosterone Replacement Therapy) still needs better…
Protein sufficiency supports resistance-training adaptation better than most supplement categories. The strongest support comes from Shimomura Y. et al. 2006, but the practical rating stays bounded by study size, replication, and how…
Soh 2024 anchors the most relevant signal. Glycine fits strength power because glycine participates in sleep signaling, glutathione, collagen, methylation, and nervous-system balance, depending on the endpoint. The score stays bounded because…
Gronfeldt 2020 supports BFR as a viable strength stimulus, but heavy loading remains more specific for competition-level max strength. The score stays bounded because Blood-Flow Restriction Training evidence for strength power can…
Tzang 2024 reports 25 RCTs and 1024 participants; lower SBP, DBP, fasting blood glucose, and triglycerides; no significant adverse-effect excess. Tzang 2024 points in the same direction, but route, dose, baseline status,…
Kemmler 2021 and Rodrigues-Santana 2023 support strength gains in adults, but Puttner 2026 found no significant added jump, sprint, or agility benefit in trained athletes. That makes Full-Body EMS more defensible when…
Whole-Body Vibration can serve as an adjunct to conventional resistance training, offering acute potentiation of muscle output without replacing a full strength program. Peng et al. 2024 reports modest improvements in concentric…
Leal-Junior 2015 supports performance and recovery effects, but Red Light Therapy is stronger for recovery than acute force output. The likely value is better readiness, less soreness, and more consistent training volume.…
Keller 2019 anchors the most relevant signal. Shilajit fits strength power when purified resin is matched to hormones, sperm parameters, strength fatigue, bone markers, or energy tracking. The score stays bounded because…
Maximal sprinting recruits fast-twitch fibers and trains anaerobic power and rate of force development in a way steady cardio never does, and Burgomaster 2005 showed sprint work boosts muscle oxidative and performance…
Talbott 2013 supports direction more than certainty. The existing rationale points to this narrower claim: the cited study reported lean-mass and strength gains in trained men, while the cited study found force…
Strength-power benefits are indirect: faster injury recovery may preserve training continuity. There is no direct strength, hypertrophy, or power RCT for TB-500. This score reflects rehabilitation continuity, not acute performance enhancement. That…
Oosterveld 2009 makes the claim plausible but incomplete. The existing rationale points to this narrower claim: Infrared sauna is not a direct strength ergogenic. It may improve recovery, relaxation, and connective-tissue comfort,…
Carrying 20 to 45 lb over distance, especially uphill or on stairs, loads the legs, hips, and posterior chain enough to build muscular endurance and modest strength in untrained and detrained people,…
Demidenko 2021 makes the claim plausible but incomplete. The existing rationale points to this narrower claim: Indirect support from frailty and muscle-health mechanisms, but no trained-athlete strength or power RCT. That does…
The existing rationale points to this narrower claim: this verified source supports the direction that meaningful dehydration impairs performance, but the audit did not verify v0's specific percentage decrement. That does not…
PEMF is not a primary strength tool. Any strength or power benefit is likely secondary to less pain, less swelling, or improved ability to train. Resistance training, creatine, protein, and sleep remain…
The evidence points to a plausible use case without proving a universal response. Ferreira et al. 2025 is the best anchor here because it reports overview of 11 systematic reviews, 151 original…
Kumar 2023 reported significant grip-strength and chair-rise improvements in older adults, a genuine functional endpoint. The signal is real but limited to small trials in an older, glutathione-depleted population, so it may…
Jacobs 2003 resistance training study (n=13 males) showed first-set leg press reps improved from 13 to 19 with caffeine plus ephedrine, but effect diminished in subsequent sets. Useful for acute single-effort attempts;…
Functional strength improved alongside lean mass in the pivotal trials, which is more than most anabolic compounds can show. The healthy-elderly study reported a 15.1% gain in stair-climb power at 3 mg…
Potential mild interference with hypertrophy and training adaptation; no strong human strength-performance benefit.
The middle-aged ATLAS trial reported strength signal at 500 mg/day, but the finding is single-source and industry-linked. Independent replication would materially raise confidence.
Strength-power is not a primary methylene blue use case. ATP-restoration logic does not replace resistance-training evidence, and no athletic performance RCT was verified. This remains below neutral because the consumer claim is…
Norwegian 4x4 recruits lower-body power under fatigue but is not a primary strength stimulus. Keep squats, hinges, loaded carries, or sprinting if strength-power is the goal.
Semaglutide can compromise strength if lean mass falls; resistance training and protein are required to keep this from turning negative.
Tesamorelin may improve lean tissue quality in responders, as in Adrian 2019, but lean mass or muscle-density changes do not automatically translate into maximal strength or power output.
Athlete RCTs show mitochondrial and performance signals in narrow cohorts. Hadanny 2022 reports performance and mitochondrial endpoint changes in middle-aged athletes. Strength and power outcomes are not consistently established. Healthy lifters and…
Indirect strength support through reduced oxidative stress and damage markers. No meaningful direct strength RCT base.
Walton 2019 found resistance-training hypertrophy blunting in older adults using metformin. This is a meaningful negative signal for lifters and strength-focused healthy users.
Omi 2019 used EMIQ plus protein powder in 40 male athletes during resistance training and reported body composition benefits. Direct strength or power output evidence is thin. No quercetin-only resistance-training RCT showed…
Strength evidence is indirect. Igarashi 2022 found muscle-function changes in older men, but Pencina 2023 did not show strength or fatigability improvement.
Strength may fall if lean mass and training performance decline during appetite suppression or gastrointestinal titration; not a strength intervention.
SLU-PP-332 appears biased toward oxidative fiber and endurance programs, not hypertrophy or power. Billon et al. 2023 supports a slow-twitch-style signal, which may not improve strength or explosive performance.
Supports training via faster recovery from musculoskeletal injury. BPC-157 is not proven to directly increase strength or power output.
Omega-3 does not consistently improve maximal force, 1RM, or explosive power. Training, protein, sleep, and creatine dominate this lane.
May support muscle function via bioenergetics, and Forzinity approval uses knee extensor strength, but healthy strength or athletic power evidence is not established.
Not a strength or power aid. No meaningful human data supports use for resistance performance; ketones are an endurance-fuel concept, not an anabolic one.
Grip strength rose about 40% in aged mice (Dimet-Wiley 2024), though other force measures did not change and no human data exists.
Nothing matches those filters.
Monthly out-of-pocket cost at the most accessible legitimate channel, at the dose the score was given for. 12 of 41 are not priced yet; those cells are left blank rather than guessed.
| Intervention | Monthly cost | At dose | How you get it |
|---|---|---|---|
| Creatine Monohydrate | Not priced yet | ||
| Essential Amino Acids | Not priced yet | ||
| TRT (Testosterone Replacement Therapy) | $50–$300 | Clinician-selected formulation at the lowest dose likely to restore physiologic testosterone | Prescription |
| Grass-Fed Whey Protein | $40–$80 | 20-40 g protein | Over the counter |
| Glycine | $2–$3 | 3 g oral glycine | Over the counter |
| Blood-Flow Restriction Training | Not priced yet | ||
| Taurine | $3–$10 | 1-3 g, 30-60 minutes before sleep | Over the counter |
| Full-Body EMS | Not priced yet | ||
| Whole-Body Vibration | $50–$100 | 30 Hz, roughly 0.3g, 10-20 min standing | Over the counter |
| Red Light Therapy | $17–$43 | 10-20 min at 6-12 inches, full chest/face/back rotation | Over the counter |
| Shilajit | $25–$50 | 500 mg purified shilajit | Over the counter |
| Sprinting (Sprint Interval Training) | Not priced yet | ||
| Tongkat Ali | $20–$40 | 200 mg/day Physta standardized extract | Over the counter |
| TB-500 (Thymosin Beta-4 Fragment) | Not priced yet | ||
| Infrared Sauna | $36–$73 | 55-60 degrees C, 20-30 min | Over the counter |
| Rucking (Weighted Walking) | Not priced yet | ||
| Ca-AKG (Calcium Alpha-Ketoglutarate) | $15–$30 | 1 g/day generic Ca-AKG oral | Over the counter |
| Electrolytes | Not priced yet | ||
| PEMF (Pulsed Electromagnetic Field Therapy) | $3–$117 | 20-30 min mat session | Over the counter |
| Ashwagandha | $15–$30 | 300 mg KSM-66 with breakfast and 300 mg with dinner | Over the counter |
| GlyNAC (Glycine + N-Acetylcysteine) | $10–$30 | Glycine and NAC at ~100 mg/kg/day each | Over the counter |
| Ephedrine | Not priced yet | ||
| Ostarine (MK-2866 / enobosarm) | Not priced yet | ||
| Rapamycin | $15–$50 | 3 mg | Prescription |
| Urolithin A | $50–$100 | 500 mg/day | Over the counter |
| Methylene Blue | $13–$40 | 0.5-5 mg oral | Over the counter |
| Norwegian 4×4 | Not priced yet | Over the counter | |
| Semaglutide | $199–$349 | 0.25 mg weeks 1 to 4, 0.5 mg weeks 5 to 8, 1.0 mg weeks 9 to 12, 1.7 mg weeks 13 to 16, 2.4 mg week 17 onward | Prescription |
| Tesamorelin | $250–$500 | 2 mg subcutaneous daily in the evening | Prescription |
| Hyperbaric Oxygen Therapy | $3,000–$6,000 | 2.0 ATA for 90 minutes with air breaks | In clinic |
| Astaxanthin | Not priced yet | ||
| Metformin | $4–$30 | 500 mg with dinner for 1 week, then 500 mg twice daily for 1 week, then increase by 500 mg/week toward 1000 mg twice daily as tolerated | Prescription |
| Quercetin | $20–$50 | 200 mg/day | Over the counter |
| NMN (Nicotinamide Mononucleotide) | $40–$100 | 500 mg/day oral | Over the counter |
| Tirzepatide | $299–$449 | 2.5 to 5 to 7.5 to 10 to 12.5 to 15 mg | Prescription |
| SLU-PP-332 | $30–$80 | 3-5 mg/day oral | Research use only |
| BPC-157 | $40–$80 | 250 to 500 mcg SC 1 to 2x/day near injury site | Grey market |
| Omega-3 | $20–$40 | 1-2 g/day combined EPA+DHA | Over the counter |
| SS-31 (Elamipretide) | $200–$500 | 5-10 mg/day subcutaneous | Grey market |
| Exogenous Ketones | $38–$300 | Ester 10 to 25 g BHB | Over the counter |
| 5-Amino-1MQ | $95–$190 | 50 to 100 mg oral, once daily | Grey market |
Head-to-head reports and category rankings that name a winner on this use case.
This page ranks by hormonal fit, not overall BioHarmony score. TRT leads at 9.0–9.5/10. Phosphatidylserine sits fifth at 5.5–6.0/10 despite the second highest overall score here, 7.0–7.5/10. That…
Shilajit scores 7.0–7.5/10 and ashwagandha 6.5–7.0/10, but that gap is the least useful number here. These two do different jobs. Shilajit is the mineral and androgen play: male…
Spermidine scores 7.5–8.0/10 and urolithin A 6.5–7.0/10, and they clean up different messes. Spermidine drives broad autophagy: autophagy 8.0/10, cardiovascular 7.8/10, longevity 7.5/10. Urolithin A drives selective mitophagy…
Ashwagandha scores 6.5–7.0/10 and tongkat ali 6.5–7.0/10, so the overall numbers do not decide it. Pick ashwagandha when stress, anxiety, or sleep is the complaint: its subratings there…
Metformin scores 6.5–7.0/10 and berberine 6.5–7.0/10, so the gap is meaningless. Metformin owns blood sugar with decades of outcome trials behind it. Berberine owns fatty liver, needs no…
Whey scores 8.0–8.5/10 and collagen 7.4/10, but they do different jobs. Whey is a complete protein that builds muscle. Collagen has no tryptophan, so it cannot. Pick whey…
Creatine Monohydrate, at 8.5–9.0 out of 10 for strength and power. Lanhers 2015 reports Lower-limb global SMD 0.235 (small-to-moderate).
Of the top-scoring options, Glycine is the least expensive at about $2 a month, scoring 6.5–7.0 out of 10 for strength and power.
41 of the 101 interventions evaluated for strength and power score 3.0 out of 10 or better, which is the cut-off for appearing on this page.
