Best Interventions for Strength and Power, Ranked by Evidence

Every intervention Outliyr has scored for strength and power, ranked by its BioHarmony score for this use case rather than its overall rating. The number beside each name is how well that one thing works for strength and power; the tier beside it is what it is worth once safety, cost and effort are counted across everything else.

40 of 88 evaluated interventions score 3.0+ out of 10 for strength and power · 6 comparisons

Ranked for Strength and Power

Category
  1. Creatine Monohydrate

    8.6 /10 for strength and power 8.7/10 overall Strong recommend Vitamin & Mineral & Nutrient

    Creatine Monohydrate earns 8.6/10 for strength and power because Lanhers 2015 reports Lower-limb global SMD 0.235 (small-to-moderate). Chilibeck 2017 points in the same direction, but route, dose, baseline status, and outcome tracking…

    Read the Creatine Monohydrate report →
  2. Essential Amino Acids

    7.8 /10 for strength and power 8.0/10 overall Strong recommend Amino Acid

    The strongest strength and power argument for Essential Amino Acids is 7.8/10 because Hagiyama 2024 reports 12 RCTs; 622 patients; low-certainty improvement in patient-reported outcomes and very-low-certainty strength signal after lower-limb surgeries.…

    Read the Essential Amino Acids report →
  3. TRT (Testosterone Replacement Therapy)

    7.5 /10 for strength and power 5.7/10 overall Neutral Pharmaceutical & Drug

    Mechanistically, TRT (Testosterone Replacement Therapy) fits strength and power at 7.5/10 because Bhasin 1996 reports Classic androgen dose-response trial; supports anabolic mechanism but used supraphysiologic dosing in normal men, not standard TRT.…

    Read the TRT (Testosterone Replacement Therapy) report →
  4. Grass-Fed Whey Protein

    7.0 /10 for strength and power 8.3/10 overall Strong recommend Vitamin & Mineral & Nutrient

    Grass-Fed Whey Protein scores 7.0/10 for strength power because protein sufficiency supports resistance-training adaptation better than most supplement categories. The strongest support comes from Shimomura Y. et al. 2006, but the practical…

    Read the Grass-Fed Whey Protein report →
  5. Glycine

    6.8 /10 for strength and power 7.9/10 overall Strong recommend Vitamin & Mineral & Nutrient

    Glycine strength power earns 6.8/10 because Soh 2024 anchors the most relevant signal. Glycine fits strength power because glycine participates in sleep signaling, glutathione, collagen, methylation, and nervous-system balance, depending on the…

    Read the Glycine report →
  6. Blood-Flow Restriction Training

    6.5 /10 for strength and power 8.2/10 overall Strong recommend Resistance & Strength

    Strength Power is a 6.5/10 fit for Blood-Flow Restriction Training, based on the evidence summarized in Liu et al. 2024. Gronfeldt 2020 supports BFR as a viable strength stimulus, but heavy loading…

    Read the Blood-Flow Restriction Training report →
  7. Taurine

    6.5 /10 for strength and power 8.1/10 overall Strong recommend Vitamin & Mineral & Nutrient

    Taurine looks most relevant to strength and power at 6.5/10 because Tzang 2024 reports 25 RCTs and 1024 participants; lower SBP, DBP, fasting blood glucose, and triglycerides; no significant adverse-effect excess. Tzang…

    Read the Taurine report →
  8. Full-Body EMS

    6.5 /10 for strength and power 7.3/10 overall Strong recommend Resistance & Strength

    Full-Body EMS gets 6.5/10 for strength power; the evidence supports a narrow read. Kemmler 2021 and Rodrigues-Santana 2023 support strength gains in adults, but Puttner 2026 found no significant added jump, sprint,…

    Read the Full-Body EMS report →
  9. Whole-Body Vibration

    6.5 /10 for strength and power 7.3/10 overall Strong recommend Other Device

    Strength-power with Whole-Body Vibration scores 6.5/10, based on data from Peng et al. 2024. Whole-Body Vibration can serve as an adjunct to conventional resistance training, offering acute potentiation of muscle output without…

    Read the Whole-Body Vibration report →
  10. Red Light Therapy

    6.2 /10 for strength and power 8.0/10 overall Strong recommend Light Therapy

    Strength-power lands at 6.2/10 because Leal-Junior 2015 supports performance and recovery effects, but Red Light Therapy is stronger for recovery than acute force output. The likely value is better readiness, less soreness,…

    Read the Red Light Therapy report →
  11. Shilajit

    6.0 /10 for strength and power 7.4/10 overall Strong recommend Adaptogenic Herb

    Shilajit strength power earns 6.0/10 because Keller 2019 anchors the most relevant signal. Shilajit fits strength power when purified resin is matched to hormones, sperm parameters, strength fatigue, bone markers, or energy…

    Read the Shilajit report →
  12. Sprinting (Sprint Interval Training)

    6.0 /10 for strength and power 6.9/10 overall Worth trying Cardiovascular

    Strength and power earn 6.0/10. Maximal sprinting recruits fast-twitch fibers and trains anaerobic power and rate of force development in a way steady cardio never does, and Burgomaster 2005 showed sprint work…

    Read the Sprinting (Sprint Interval Training) report →
  13. Tongkat Ali

    5.8 /10 for strength and power 7.0/10 overall Strong recommend Adaptogenic Herb

    A 5.8/10 for strength-power fits Tongkat Ali because Talbott 2013 supports direction more than certainty. The existing rationale points to this narrower claim: the cited study reported lean-mass and strength gains in…

    Read the Tongkat Ali report →
  14. TB-500 (Thymosin Beta-4 Fragment)

    5.5 /10 for strength and power 7.5/10 overall Strong recommend Growth & Repair Peptide

    TB-500 (Thymosin Beta-4 Fragment) earns 5.5/10 for strength power; this is a targeted fit score. Strength-power benefits are indirect: faster injury recovery may preserve training continuity. There is no direct strength, hypertrophy,…

    Read the TB-500 (Thymosin Beta-4 Fragment) report →
  15. Infrared Sauna

    5.5 /10 for strength and power 7.4/10 overall Strong recommend Sauna & Heat Therapy

    On strength-power, Infrared Sauna deserves 5.5/10 because Oosterveld 2009 makes the claim plausible but incomplete. The existing rationale points to this narrower claim: Infrared sauna is not a direct strength ergogenic. It…

    Read the Infrared Sauna report →
  16. Rucking (Weighted Walking)

    5.5 /10 for strength and power 7.3/10 overall Strong recommend Cardiovascular

    Strength scores 5.5. Carrying 20 to 45 lb over distance, especially uphill or on stairs, loads the legs, hips, and posterior chain enough to build muscular endurance and modest strength in untrained…

    Read the Rucking (Weighted Walking) report →
  17. Ca-AKG (Calcium Alpha-Ketoglutarate)

    5.5 /10 for strength and power 6.5/10 overall Worth trying Vitamin & Mineral & Nutrient

    On strength-power, Ca-AKG (Calcium Alpha-Ketoglutarate) deserves 5.5/10 because Demidenko 2021 makes the claim plausible but incomplete. The existing rationale points to this narrower claim: Indirect support from frailty and muscle-health mechanisms, but…

    Read the Ca-AKG (Calcium Alpha-Ketoglutarate) report →
  18. Electrolytes

    5.0 /10 for strength and power 8.8/10 overall Top-tier Vitamin & Mineral & Nutrient

    Electrolytes's 5.0/10 strength-power score starts with Borra 2025, then gets narrowed by the evidence gap. The existing rationale points to this narrower claim: this verified source supports the direction that meaningful dehydration…

    Read the Electrolytes report →
  19. PEMF (Pulsed Electromagnetic Field Therapy)

    5.0 /10 for strength and power 7.5/10 overall Strong recommend PEMF

    PEMF (Pulsed Electromagnetic Field Therapy) fits strength power at 5.0/10 when the baseline problem is real. PEMF is not a primary strength tool. Any strength or power benefit is likely secondary to…

    Read the PEMF (Pulsed Electromagnetic Field Therapy) report →
  20. Ashwagandha

    5.0 /10 for strength and power 6.8/10 overall Worth trying Adaptogenic Herb

    The strength power case for Ashwagandha lands at 5.0/10 because the evidence points to a plausible use case without proving a universal response. Ferreira et al. 2025 is the best anchor here…

    Read the Ashwagandha report →
  21. GlyNAC (Glycine + N-Acetylcysteine)

    5.0 /10 for strength and power 6.7/10 overall Worth trying Amino Acid

    Strength scores 5.0/10 because Kumar 2023 reported significant grip-strength and chair-rise improvements in older adults, a genuine functional endpoint. The signal is real but limited to small trials in an older, glutathione-depleted…

    Read the GlyNAC (Glycine + N-Acetylcysteine) report →
  22. Ephedrine

    5.0 /10 for strength and power 5.3/10 overall Neutral Pharmaceutical & Drug

    For readers prioritizing strength power, Ephedrine scores 5.0/10 today. Jacobs 2003 resistance training study (n=13 males) showed first-set leg press reps improved from 13 to 19 with caffeine plus ephedrine, but effect…

    Read the Ephedrine report →
  23. Rapamycin

    4.5 /10 for strength and power 6.8/10 overall Worth trying Pharmaceutical & Drug

    Potential mild interference with hypertrophy and training adaptation; no strong human strength-performance benefit.

    Read the Rapamycin report →
  24. Urolithin A

    4.5 /10 for strength and power 6.5/10 overall Worth trying Exogenous Metabolite

    The middle-aged ATLAS trial reported strength signal at 500 mg/day, but the finding is single-source and industry-linked. Independent replication would materially raise confidence.

    Read the Urolithin A report →
  25. Methylene Blue

    4.5 /10 for strength and power 6.1/10 overall Worth trying Pharmaceutical & Drug

    Strength-power is not a primary methylene blue use case. ATP-restoration logic does not replace resistance-training evidence, and no athletic performance RCT was verified. This remains below neutral because the consumer claim is…

    Read the Methylene Blue report →
  26. Norwegian 4×4

    4.0 /10 for strength and power 8.5/10 overall Strong recommend Cardiovascular

    Norwegian 4x4 recruits lower-body power under fatigue but is not a primary strength stimulus. Keep squats, hinges, loaded carries, or sprinting if strength-power is the goal.

    Read the Norwegian 4×4 report →
  27. Tesamorelin

    4.0 /10 for strength and power 6.2/10 overall Worth trying Growth Hormone Secretagogue

    Tesamorelin may improve lean tissue quality in responders, as in Adrian 2019, but lean mass or muscle-density changes do not automatically translate into maximal strength or power output.

    Read the Tesamorelin report →
  28. Semaglutide

    4.0 /10 for strength and power 6.0/10 overall Worth trying Metabolic & Incretin Peptide

    Semaglutide can compromise strength if lean mass falls; resistance training and protein are required to keep this from turning negative.

    Read the Semaglutide report →
  29. Hyperbaric Oxygen Therapy

    3.7 /10 for strength and power 6.2/10 overall Worth trying Hyperbaric

    Athlete RCTs show mitochondrial and performance signals in narrow cohorts. Hadanny 2022 reports performance and mitochondrial endpoint changes in middle-aged athletes. Strength and power outcomes are not consistently established. Healthy lifters and…

    Read the Hyperbaric Oxygen Therapy report →
  30. Astaxanthin

    3.5 /10 for strength and power 7.8/10 overall Strong recommend Vitamin & Mineral & Nutrient

    Indirect strength support through reduced oxidative stress and damage markers. No meaningful direct strength RCT base.

    Read the Astaxanthin report →
  31. Metformin

    3.5 /10 for strength and power 6.9/10 overall Worth trying Other Pharmaceutical

    Walton 2019 found resistance-training hypertrophy blunting in older adults using metformin. This is a meaningful negative signal for lifters and strength-focused healthy users.

    Read the Metformin report →
  32. Quercetin

    3.5 /10 for strength and power 6.8/10 overall Worth trying Botanical Extract (non-adaptogenic)

    Omi 2019 used EMIQ plus protein powder in 40 male athletes during resistance training and reported body composition benefits. Direct strength or power output evidence is thin. No quercetin-only resistance-training RCT showed…

    Read the Quercetin report →
  33. NMN (Nicotinamide Mononucleotide)

    3.5 /10 for strength and power 6.3/10 overall Worth trying Exogenous Metabolite

    Strength evidence is indirect. Igarashi 2022 found muscle-function changes in older men, but Pencina 2023 did not show strength or fatigability improvement.

    Read the NMN (Nicotinamide Mononucleotide) report →
  34. Tirzepatide

    3.5 /10 for strength and power 6.1/10 overall Worth trying Metabolic & Incretin Peptide

    Strength may fall if lean mass and training performance decline during appetite suppression or gastrointestinal titration; not a strength intervention.

    Read the Tirzepatide report →
  35. SLU-PP-332

    3.5 /10 for strength and power 4.7/10 overall Neutral Research Compound

    SLU-PP-332 appears biased toward oxidative fiber and endurance programs, not hypertrophy or power. Billon et al. 2023 supports a slow-twitch-style signal, which may not improve strength or explosive performance.

    Read the SLU-PP-332 report →
  36. BPC-157

    3.0 /10 for strength and power 7.5/10 overall Strong recommend Growth & Repair Peptide

    Supports training via faster recovery from musculoskeletal injury. BPC-157 is not proven to directly increase strength or power output.

    Read the BPC-157 report →
  37. Omega-3

    3.0 /10 for strength and power 6.8/10 overall Worth trying Vitamin & Mineral & Nutrient

    Omega-3 does not consistently improve maximal force, 1RM, or explosive power. Training, protein, sleep, and creatine dominate this lane.

    Read the Omega-3 report →
  38. SS-31 (Elamipretide)

    3.0 /10 for strength and power 6.0/10 overall Worth trying Mitochondrial & Longevity Peptide

    May support muscle function via bioenergetics, and Forzinity approval uses knee extensor strength, but healthy strength or athletic power evidence is not established.

    Read the SS-31 (Elamipretide) report →
  39. Exogenous Ketones

    3.0 /10 for strength and power 5.9/10 overall Worth trying Exogenous Metabolite

    Not a strength or power aid. No meaningful human data supports use for resistance performance; ketones are an endurance-fuel concept, not an anabolic one.

    Read the Exogenous Ketones report →
  40. 5-Amino-1MQ

    3.0 /10 for strength and power 4.9/10 overall Neutral Research Compound

    Grip strength rose about 40% in aged mice (Dimet-Wiley 2024), though other force measures did not change and no human data exists.

    Read the 5-Amino-1MQ report →

Comparisons that judge strength and power

Head-to-head reports and category rankings that name a winner on this use case.

Questions about strength and power

What scores highest for strength and power?

Creatine Monohydrate, at 8.6 out of 10 for strength and power. Creatine Monohydrate earns 8.6/10 for strength and power because Lanhers 2015 reports Lower-limb global SMD 0.235 (small-to-moderate).

What is the cheapest thing that works for strength and power?

Of the top-scoring options, Glycine is the least expensive at about $2 a month, scoring 6.8 out of 10 for strength and power.

How many interventions has Outliyr scored for strength and power?

40 of the 88 interventions evaluated for strength and power score 3.0 out of 10 or better, which is the cut-off for appearing on this page.