Finding the best biohacking supplements is overwhelming. Thousands of brands make bold claims, yet most use cheap fillers, underdosed ingredients, or proprietary blends that hide what you are actually getting. I have spent years testing health optimization supplements firsthand — tracking biomarkers, monitoring subjective effects, and comparing formulations — so you do not have to wade through the noise.
This collection features my top-rated supplements for cognitive performance, energy, recovery, longevity, and overall vitality. Every product here meets strict criteria: third-party testing, bioavailable forms, transparent labeling, and ingredients backed by peer-reviewed research. From nootropic supplements that sharpen focus to adaptogens that build resilience, these are the formulations I actually use and recommend as a Certified Personal Trainer who works with high performers.
Many of these brands offer exclusive Outliyr discount codes, saving you anywhere from 10 to 20 percent off retail. Browse the full lineup below to find the right supplement stack for your goals.
Supplements Comparison
| Product | Best For | Price | Discount | Rating | |
|---|---|---|---|---|---|
| 5-Amino-1MQ | a cutting-edge compound targeting fat metabolism and cellular energy | URBAN14.8% off | ★★★½☆ | Get Deal | |
| 9-Me-BC | potent dopaminergic support for motivation and focus | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Ease Magnesium | You experience muscle cramps, soreness, or tension and want targeted relief | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Oceans Alive | Activation Products' flagship phytoplankton blend | URBAN15% off | ★★★½☆ | Get Deal | |
| Adapt Naturals Bio-Avail Colostrum+ | Readers wanting colostrum plus added lactoferrin and beta-glucan | — | — | — | Get Best Price |
| Amino Co EAAs | to support muscle recovery and protein synthesis | URBAN30.7% off | ★★★★☆ | Get Deal | |
| ARMRA Colostrum Health Revival | Readers who want the most established consumer colostrum brand | — | — | Get Best Price | |
| ARMRA Colostrum Performance Revival | Athletes seeking colostrum plus workout-recovery ingredients | — | — | Get Best Price | |
| Auro Wellness Glutaryl | Readers who prefer a topical glutathione spray | URBAN10% off | — | Get Deal | |
| AX3 Bio-Pure Astaxanthin | Anyone wanting a research-backed astaxanthin with proven bioavailability, esp… | URBAN20% off | ★★★★☆ | Get Deal | |
| BIOptimizers Berberine Breakthrough | Nick’s top overall berberine formula | URBAN10% off | ★★★½☆ | Get Deal | |
| BiOptimizers Magnesium Breakthrough | comprehensive magnesium support from multiple forms | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers MassZymes | You experience bloating, gas, or discomfort after meals | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers Probiotic Breakthrough (formerly P3-OM) | — | URBAN10% off | ★★★★½ | Get Deal | |
| Black Lotus Shilajit | a mineral-rich daily supplement with fulvic acid | URBAN15% off | ★★★★☆ | Get Deal | |
| Bloom Nutrition Colostrum + Collagen | Readers prioritizing convenience over specialized full-dose products | — | — | — | Get Best Price |
| Blue Cannatine | targeted nutritional support for your specific health goals | URBAN10% off | ★★★★☆ | Get Deal | |
| Blue Sky Peptides | Budget buyers who prioritize low prices and frequent deals, and are comfortab… | $39.95 | — | ★★½☆☆ | Get Best Price |
| BodyBio E-Lyte | high-potassium electrolytes | URBAN15% off | ★★★★☆ | Get Deal | |
| BodyBio Liposomal Glutathione | a premium liposomal glutathione from a trusted brand | URBAN15.5% off | — | Get Deal | |
| Botanabolic | multi-mechanism testosterone optimization with botanical androgens | URBAN14.8% off | ★★★★☆ | Get Deal | |
| C8 MCT Oil | targeted nutritional support for your specific health goals | URBAN27.8% off | ★★★★☆ | Get Deal | |
| Chemyo | SARMs researchers who prioritize verified purity, transparent testing, and a … | $59.99 | — | — | Get Best Price |
| Codeage Liposomal Urolithin A | Readers seeking a multi-ingredient Urolithin A formula with added mitochondri… | URBAN10% off | — | Get Deal | |
| CollaGenius | cognitive support combined with beauty and anti-aging benefits | URBAN7.6% off | ★★★½☆ | Get Deal | |
| Core Peptides | Researchers who value fast shipping and custom blend options, but proceed wit… | $47 | — | ★★★★☆ | Get Best Price |
| Cortisol Balance | targeted cortisol management with clinically studied ingredients | $60 | — | ★★★★☆ | Get Best Price |
| Cosmic Nootropic | International readers seeking rare pharmaceutical nootropics | URBAN55% off | — | Get Deal | |
| Cowboy Colostrum Nature's Gold | Readers wanting a straightforward first-milking colostrum with flavor options | — | — | — | Get Best Price |
| Crevolution | creatine, GAA and TMG in one unflavored scoop | URBAN15% off | — | Get Deal | |
| D3K2 ReSet | D3 and K2 in proper ratio from a trusted brand | URBAN10% off | — | Get Deal | |
| Do Not Age Spermidine | Longevity enthusiasts who want to support autophagy and cellular renewal thro… | $39 | — | ★★★½☆ | Get Best Price |
| DoNotAge Pure NR | International buyers seeking a high-dose bulk NR capsule | — | — | — | Get Best Price |
| Double Wood Berberine | an affordable 500 mg berberine HCl capsule | $19.95 | — | ★★★★☆ | Get Best Price |
| Double Wood Resveratrol | Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol … | $19.95 | — | ★★★½☆ | Get Best Price |
| Double Wood Spermidine | Those who want a high-dose pure spermidine supplement at a competitive price … | $39.95 | — | ★★★★☆ | Get Best Price |
| Dream Optimizer | Readers who want a fast, convenient spray for occasional nighttime wakeups | URBAN15% off | — | Get Deal | |
| Earth Circle Organics Chlorella | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina + Chlorella | a whole-food plant-based source of vitamins, minerals, and protein | NICKURBAN20% off | ★★★★☆ | Get Deal | |
| Ergothioneine | targeted nutritional support for your specific health goals | — | ★★★½☆ | Get Best Price | |
| Essential C Complex | — | — | — | Get Best Price | |
| Folqs First-Day Milking Bovine Colostrum | to strengthen your gut lining and immune defenses naturally | URBAN10% off | ★★★★☆ | Get Deal | |
| Healthgevity bioREPAIR | Readers wanting a targeted capsule formula for gut-barrier support | URBAN10% off | — | Get Deal | |
| Healthgevity IGNITE+ | metabolic support for glucose regulation and body composition | URBAN10% off | ★★★½☆ | Get Deal | |
| Healthgevity Rejuvenate 2.0 | Serious longevity enthusiasts who want a comprehensive multi-pathway senolyti… | $124.99 | — | ★★★★½ | Get Best Price |
| Hergevity Balance | hormone support through estrogen receptor-beta signaling without direct hormo… | URBAN9.3% off | ★★★★☆ | Get Deal | |
| HighStreetPharma | Readers who already have appropriate medical guidance and seek established ge… | $30 | — | — | Get Best Price |
| InfiniFiber | broad prebiotic fiber diversity plus a probiotic in a single scoop | $54.99 | — | ★★★★½ | Get Best Price |
| Infiniwell Senolytic | Budget-conscious biohackers wanting a proven senolytic formula without premiu… | $69.95 | — | ★★★★☆ | Get Best Price |
Performance Lab Sleep v2
- Best for
- Readers who want a clean-label capsule with magnesium, tart cherry, tryptophan, and lemon balm
- Skip if
- You avoid all sources of melatonin or prefer a single-ingredient product
Details checked 06/09/2026
Get Best PriceLVLUP Health Urolithin A + Akkermansia
- Best for
- Readers who want one formula targeting both mitochondrial and gut health
- Skip if
- You want a clinically studied 500 to 1,000 mg single-ingredient Urolithin A dose
Details checked 06/09/2026
Get Best PriceLiftMode Urolithin A Powder
- Best for
- Readers who want flexible dosing and pure bulk powder
- Skip if
- You prefer pre-measured capsules or sachets
Details checked 06/09/2026
Get Best PriceNeurogan Urolithin A Pro Capsules
- Best for
- Readers seeking a high-dose, lower-cost capsule formula
- Skip if
- You want the exact branded ingredient used in Mitopure clinical trials
Details checked 06/09/2026
Get Best PriceTimeline Nutrition Mitopure Powder Sachets
- Best for
- Readers who prefer mixing Mitopure into drinks or food
- Skip if
- You want tasteless capsules or an unflavored powder
Details checked 06/09/2026
Get Best PricePerpetua.Life Urolithin-A
- Best for
- Readers seeking a high-dose liposomal Urolithin A formula
- Skip if
- You prefer the exact branded ingredient used in published Mitopure trials
Details checked 06/09/2026
Get Best PriceTimeline Nutrition Urolithin A Mitopure Softgels
- Best for
- Readers prioritizing the strongest human evidence for Urolithin A
- Skip if
- You want a lower-cost generic Urolithin A product
Details checked 06/09/2026
Get Best PriceTransparent Labs Grass-Fed Colostrum
- Best for
- Athletes and readers seeking the highest-dose colostrum powder
- Skip if
- You prioritize first-day milking or explicitly cold-processed colostrum
Details checked 06/09/2026
Healthgevity bioREPAIR
- Best for
- Readers wanting a targeted capsule formula for gut-barrier support
- Skip if
- You want whole bovine colostrum powder or a lower cost per gram
Details checked 06/09/2026
URBAN — 10% offDream Optimizer
- Best for
- Readers who want a fast, convenient spray for occasional nighttime wakeups
- Skip if
- You want a fully disclosed capsule or single-ingredient sleep aid
Details checked 06/09/2026
URBAN — 15% offTru Niagen Nicotinamide Riboside
- Best for
- Readers prioritizing the strongest product-specific NR evidence
- Skip if
- You want the cheapest NR or an all-in-one longevity formula
Details checked 06/09/2026
ARMRA Colostrum Health Revival
- Best for
- Readers who want the most established consumer colostrum brand
- Skip if
- You prioritize maximum grams per dollar
Details checked 06/09/2026
Sleep Breakthrough
- Best for
- Readers who want a melatonin-free mineral powder for sleep
- Skip if
- You prefer capsules or an unflavored single-ingredient supplement
Details checked 06/09/2026
URBAN — 15% offUltra Health Liposomal Nicotinamide Riboside
- Best for
- Readers prioritizing an enhanced-delivery NR capsule
- Skip if
- You want the most extensively studied branded NR ingredient
Details checked 06/09/2026
NC15 — 15% offOrganifi Colostrum
- Best for
- Beginners wanting a simple, ethically sourced colostrum powder
- Skip if
- You require disclosed IgG standardization or cold-processing details
Details checked 06/09/2026
URBAN — 15% offARMRA Colostrum Performance Revival
- Best for
- Athletes seeking colostrum plus workout-recovery ingredients
- Skip if
- You want plain colostrum or the lowest price per gram
Details checked 06/09/2026
RECOVERYbits Chlorella
- Best for
- Readers wanting premium single-ingredient chlorella tablets
- Skip if
- You want a budget powder or dislike swallowing many tablets
Details checked 06/09/2026
NICKURBAN — 20% offCosmic Nootropic
- Best for
- International readers seeking rare pharmaceutical nootropics
- Skip if
- You need a domestic US supplement vendor or conventional natural supplements
Details checked 06/09/2026
URBAN5 — 5% offHighStreetPharma
- Best for
- Readers who already have appropriate medical guidance and seek established generic afinil brands
- Skip if
- You want over-the-counter natural nootropics or cannot legally import prescription products
Details checked 06/09/2026
Codeage Liposomal Urolithin A
- Best for
- Readers seeking a multi-ingredient Urolithin A formula with added mitochondrial support
- Skip if
- You want a single-ingredient formula used in published Mitopure trials
Details checked 06/09/2026
URBAN — 10% off


















