Finding the best biohacking supplements is overwhelming. Thousands of brands make bold claims, yet most use cheap fillers, underdosed ingredients, or proprietary blends that hide what you are actually getting. I have spent years testing health optimization supplements firsthand — tracking biomarkers, monitoring subjective effects, and comparing formulations — so you do not have to wade through the noise.
This collection features my top-rated supplements for cognitive performance, energy, recovery, longevity, and overall vitality. Every product here meets strict criteria: third-party testing, bioavailable forms, transparent labeling, and ingredients backed by peer-reviewed research. From nootropic supplements that sharpen focus to adaptogens that build resilience, these are the formulations I actually use and recommend as a Certified Personal Trainer who works with high performers.
Many of these brands offer exclusive Outliyr discount codes, saving you anywhere from 10 to 20 percent off retail. Browse the full lineup below to find the right supplement stack for your goals.
Supplements Comparison
| Product | Best For | Price | Discount | Rating | |
|---|---|---|---|---|---|
| 5-Amino-1MQ | a cutting-edge compound targeting fat metabolism and cellular energy | URBAN14.8% off | ★★★½☆ | Get Deal | |
| 9-Me-BC | potent dopaminergic support for motivation and focus | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Ease Magnesium | You experience muscle cramps, soreness, or tension and want targeted relief | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Oceans Alive | Activation Products' flagship phytoplankton blend | URBAN15% off | ★★★½☆ | Get Deal | |
| Adapt Naturals Bio-Avail Colostrum+ | Readers wanting colostrum plus added lactoferrin and beta-glucan | — | — | — | Get Best Price |
| Amino Co EAAs | to support muscle recovery and protein synthesis | URBAN30.7% off | ★★★★☆ | Get Deal | |
| ARMRA Colostrum Health Revival | Readers who want the most established consumer colostrum brand | — | — | Get Best Price | |
| ARMRA Colostrum Performance Revival | Athletes seeking colostrum plus workout-recovery ingredients | — | — | Get Best Price | |
| Auro Wellness Glutaryl | Readers who prefer a topical glutathione spray | URBAN10% off | — | Get Deal | |
| AX3 Bio-Pure Astaxanthin | Anyone wanting a research-backed astaxanthin with proven bioavailability, esp… | URBAN20% off | ★★★★☆ | Get Deal | |
| BIOptimizers Berberine Breakthrough | Nick’s top overall berberine formula | URBAN10% off | ★★★½☆ | Get Deal | |
| BiOptimizers Magnesium Breakthrough | comprehensive magnesium support from multiple forms | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers MassZymes | You experience bloating, gas, or discomfort after meals | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers Probiotic Breakthrough (formerly P3-OM) | — | URBAN10% off | ★★★★½ | Get Deal | |
| Black Lotus Shilajit | a mineral-rich daily supplement with fulvic acid | URBAN15% off | ★★★★☆ | Get Deal | |
| Bloom Nutrition Colostrum + Collagen | Readers prioritizing convenience over specialized full-dose products | — | — | — | Get Best Price |
| Blue Cannatine | targeted nutritional support for your specific health goals | URBAN10% off | ★★★★☆ | Get Deal | |
| Blue Sky Peptides | Budget buyers who prioritize low prices and frequent deals, and are comfortab… | $39.95 | — | ★★½☆☆ | Get Best Price |
| BodyBio E-Lyte | high-potassium electrolytes | URBAN15% off | ★★★★☆ | Get Deal | |
| BodyBio Liposomal Glutathione | a premium liposomal glutathione from a trusted brand | URBAN15.5% off | — | Get Deal | |
| Botanabolic | multi-mechanism testosterone optimization with botanical androgens | URBAN14.8% off | ★★★★☆ | Get Deal | |
| C8 MCT Oil | targeted nutritional support for your specific health goals | URBAN27.8% off | ★★★★☆ | Get Deal | |
| Chemyo | SARMs researchers who prioritize verified purity, transparent testing, and a … | $59.99 | — | — | Get Best Price |
| Codeage Liposomal Urolithin A | Readers seeking a multi-ingredient Urolithin A formula with added mitochondri… | URBAN10% off | — | Get Deal | |
| CollaGenius | cognitive support combined with beauty and anti-aging benefits | URBAN7.6% off | ★★★½☆ | Get Deal | |
| Core Peptides | Researchers who value fast shipping and custom blend options, but proceed wit… | $47 | — | ★★★★☆ | Get Best Price |
| Cortisol Balance | targeted cortisol management with clinically studied ingredients | $60 | — | ★★★★☆ | Get Best Price |
| Cosmic Nootropic | International readers seeking rare pharmaceutical nootropics | URBAN55% off | — | Get Deal | |
| Cowboy Colostrum Nature's Gold | Readers wanting a straightforward first-milking colostrum with flavor options | — | — | — | Get Best Price |
| Crevolution | creatine, GAA and TMG in one unflavored scoop | URBAN15% off | — | Get Deal | |
| D3K2 ReSet | D3 and K2 in proper ratio from a trusted brand | URBAN10% off | — | Get Deal | |
| Do Not Age Spermidine | Longevity enthusiasts who want to support autophagy and cellular renewal thro… | $39 | — | ★★★½☆ | Get Best Price |
| DoNotAge Pure NR | International buyers seeking a high-dose bulk NR capsule | — | — | — | Get Best Price |
| Double Wood Berberine | an affordable 500 mg berberine HCl capsule | $19.95 | — | ★★★★☆ | Get Best Price |
| Double Wood Resveratrol | Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol … | $19.95 | — | ★★★½☆ | Get Best Price |
| Double Wood Spermidine | Those who want a high-dose pure spermidine supplement at a competitive price … | $39.95 | — | ★★★★☆ | Get Best Price |
| Dream Optimizer | Readers who want a fast, convenient spray for occasional nighttime wakeups | URBAN15% off | — | Get Deal | |
| Earth Circle Organics Chlorella | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina + Chlorella | a whole-food plant-based source of vitamins, minerals, and protein | NICKURBAN20% off | ★★★★☆ | Get Deal | |
| Ergothioneine | targeted nutritional support for your specific health goals | — | ★★★½☆ | Get Best Price | |
| Essential C Complex | — | — | — | Get Best Price | |
| Folqs First-Day Milking Bovine Colostrum | to strengthen your gut lining and immune defenses naturally | URBAN10% off | ★★★★☆ | Get Deal | |
| Healthgevity bioREPAIR | Readers wanting a targeted capsule formula for gut-barrier support | URBAN10% off | — | Get Deal | |
| Healthgevity IGNITE+ | metabolic support for glucose regulation and body composition | URBAN10% off | ★★★½☆ | Get Deal | |
| Healthgevity Rejuvenate 2.0 | Serious longevity enthusiasts who want a comprehensive multi-pathway senolyti… | $124.99 | — | ★★★★½ | Get Best Price |
| Hergevity Balance | hormone support through estrogen receptor-beta signaling without direct hormo… | URBAN9.3% off | ★★★★☆ | Get Deal | |
| HighStreetPharma | Readers who already have appropriate medical guidance and seek established ge… | $30 | — | — | Get Best Price |
| InfiniFiber | broad prebiotic fiber diversity plus a probiotic in a single scoop | $54.99 | — | ★★★★½ | Get Best Price |
| Infiniwell Senolytic | Budget-conscious biohackers wanting a proven senolytic formula without premiu… | $69.95 | — | ★★★★☆ | Get Best Price |
Showing 96 of 140 products in Supplements
BIOptimizers Berberine Breakthrough
BiOptimizers
- Best for
- You want Nick’s top overall berberine formula
- Skip if
- You take glucose-lowering medication without clinician guidance
Details checked 06/08/2026
URBAN — 10% off
Ergothioneine
Real Mushrooms
- Best for
- You want targeted nutritional support for your specific health goals
- Skip if
- You haven't optimized diet, sleep, and exercise first (they matter more)
Details checked 11/17/2025
Best Ketone Glyceride EsterTecton Ketone
Tecton
- Best for
- Pre-workout energy
- Skip if
- Need maximum ketone elevation
Details checked 03/03/2026
$96
Buy Tecton Ketone
Wizard Sciences Anti-Mx
Wizard Sciences
- Best for
- Advanced biohackers and those following a ketogenic lifestyle who want targeted mitochondrial protection and inflammation control through a novel C60-based serum.
- Skip if
- You are not following a ketogenic diet (the product requires ketosis for efficacy), or you prefer well-established supplements with extensive human clinical data.
$256
Get Best Price
Vegan Omega-3
Performance Lab
- Best for
- You follow a plant-based diet and need omega-3 support
- Skip if
- You're not vegan and prefer traditional fish oil (often more potent per capsule)
Details checked 11/11/2025
$49
Get Best Price
Limitless Tesofensine
Limitless Tesofensine
- Best for
- You want powerful appetite suppression and metabolic support
- Skip if
- You have cardiovascular conditions or high blood pressure
Details checked 11/22/2025
URBAN — 15% off
Methylene Blue
SwissChem
- Best for
- You want a mitochondrial energy booster backed by 100+ years of research
- Skip if
- You take SSRIs or serotonergic medications (risk of serotonin syndrome)
Details checked 11/23/2025
URBAN — 14.9% off
Blue Sky Peptides
Blue Sky
- Best for
- Budget buyers who prioritize low prices and frequent deals, and are comfortable with a vendor that has a longer history but mixed recent feedback.
- Skip if
- You demand full HPLC purity testing, transparent on-site reviews, or consistent quality — recent reports suggest this vendor is trending downward.
$39.95
Get Best Price
Crevolution
LVLUP Health
- Best for
- You want creatine, GAA and TMG in one unflavored scoop
- Skip if
- You want plain creatine monohydrate at the lowest cost per gram
Details checked 08/23/2026
URBAN — 15% off
D3K2 ReSet
RnA ReSet
- Best for
- You want D3 and K2 in proper ratio from a trusted brand
- Skip if
- Your vitamin D levels are already optimal from sun exposure
Details checked 08/22/2026
URBAN — 10% off
NutriGenesis Multi for Men
Performance Lab
- Best for
- You want a whole-food multivitamin with bioavailable forms
- Skip if
- You already eat a nutrient-dense whole-food diet and track your intake
Details checked 09/18/2026
$49
Get Best Price
Renue Trans-Resveratrol Powder
Renue by Science
- Best for
- Readers seeking a straightforward resveratrol product in this format
- Skip if
- You take interacting medication or expect proven longevity outcomes
Details checked 06/09/2026
Get Best Price
PerpetuaLife AEON
Perpetua.Life
- Best for
- You want one all-in-one longevity formula instead of dosing single compounds from separate bottles.
- Skip if
- You want to control the dose of each individual ingredient.
Details checked 06/08/2026
URBAN2 — 20% off
Chemyo
Chemyo
- Best for
- SARMs researchers who prioritize verified purity, transparent testing, and a vendor with years of proven reliability.
- Skip if
- You're specifically looking for peptides (BPC-157, TB-500, etc.): Chemyo's catalog is SARMs-focused. Also skip if you need discreet international shipping.
Details checked 06/09/2026
$59.99
Get Best Price
BodyBio Liposomal Glutathione
BodyBio
- Best for
- You want a premium liposomal glutathione from a trusted brand
- Skip if
- You have low toxin exposure and eat a clean diet
Details checked 08/22/2026
URBAN — 15.5% off
Auro Wellness Glutaryl
Auro Wellness
- Best for
- Readers who prefer a topical glutathione spray
- Skip if
- You want an oral product with stronger human bioavailability evidence
Details checked 08/22/2026
URBAN — 10% off
Pure Encapsulations Resveratrol
Pure Encapsulations
- Best for
- Readers seeking a straightforward resveratrol product in this format
- Skip if
- You take interacting medication or expect proven longevity outcomes
Details checked 06/09/2026
Get Best Price