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7 Top Trustworthy Supplement Brands (That You Should Use)

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Best Dietary Supplement Brands & Companies
Best Dietary Supplement Brands & Companies

Until recently, I started my day with a mountain of pills, powders, and capsules.

One day I ran out of a product and bought a new brand. The product had the same dose but the capsule doubled in size. I investigated.

Each new capsule contained fillers, excipients, and plenty of other inactive ingredients. The first product didn’t have them, so surely the second cheaper brand didn’t need them either.

It turns out that not all supplement brands or products are the same. Choosing reliable brands ensures that you receive a product with the actual active ingredients inside, no questionable fillers, and most importantly, no contaminants.

In this post I will present the best supplement brands that meet the highest purity, safety, and trustworthiness standards:

  • Certified by one of more regulatory agencies
  • Vigorous safety testing
  • Trusted by medical practitioners
  • Minimal filler
  • Products mostly made in the USA

The Wrong Supplement Manufacturer Are Worse Than Useless

Dietary supplements do not fit into the category of either food or drug, so the FDA turns a blind eye. Manufacturers notoriously cut corners whenever possible for a leg up on their rivals.

Filling this need, third-party companies evaluate products for effectiveness and safety.

Every year new headlines come out about contaminated supplements. The results of many such tests are dismal.

A study on athletes found that supplement users unintentionally consumed products adulterated with banned substances. This devastated the career of Olympic swimmer Jessica Hardy. And Jessica was proactive. Before buying she had contacted the company for safety and purity information on their products. Not an athlete?

Smart drugs, or brain-enhancing nootropics have similar issues with purity. Memory supplements contained little to no active ingredients, yet substantial contamination.

One of the larger tests of 138 common dietary supplements found worrisome levels of toxic molds, yeast, and fungi.

Another more recent 2018 study identified unapproved pharmaceutical ingredients in a staggering 776 dietary supplements. What kind of products? Those marketed for sexual enhancement, weight loss, or muscle building. From that same report:

“157 products (20.2%) contained more than 1 unapproved ingredient.”

It still happens today.

In June 2019 the FDA seized 300,000 containers of contaminated products.

Due to widespread product contamination and new untested brands bombarding store shelves, choosing a safe and reliable supplement brand is critical to your health and wellbeing.

The Best Honest Supplement Companies

My research on the below companies comes mostly from their own websites along with personal testing and third-party evaluation.

Note that I haven’t included all supplement vendors below, but rather only the biggest and most popular. You’ll find many other high-quality lab-tested supplement brands in my online shop.

Biohacker’s Favorite: BiOptimizers

bioptimizers logo

If you’ve taken supplements for any period of time, you’ve likely come across BiOptimizers. They have among the lowest return rate of any supplement company. That’s because they extensively research how to best solve their own problems and those of their clientele (pro athletes, CEOs, etc). Using the highest-quality, most bioavailable forms of nutrients (often costing them 200-400% more than their competitors). If they cannot produce the best product in its category, they don’t.

They use organic ingredients wherever possible, and manufacture in the Canda-based facility. BiOptimizers products are non-GMO; free of chemical fillers, binders, soy, dairy, and gluten; vegetarian and vegan-friendly; and backed by a generous no-questions-asked money-back guarantee.

Other notes:

  • Scientific Advisory Board includes Dom D’Agostino; Monia Avdic, PhD; Sabina Halilovic, PhD
  • They work with the Burch University in Sarajevo
  • BiOptimizers has their own probiotics lab with multiple PhDs
  • Team includes a world-class Chinese herbal expert, an elite nootropic formulator, and top enzyme scientists
Visit BiOptimizers

Save 10% with BiOptimizers code URBAN

Athlete’s Choice: Thorne Research


Trusted by 12 U.S. National teams and many professional sports teams, Thorne research provides safe, effective products free of contamination. If you can’t (or don’t want to) risk accidentally consuming banned substances, Thorne’s got you covered.

Ingredients: Free of the common magnesium stearate filler or other unwanted absorption-inhibiting ingredients


  • They test for 760 contaminants to verify the identity, potency, and purity of each ingredient on their labels
  • Throughout the production process, each product undergoes four rounds of testing
  • Thorne has an outstanding reputation among third-party certifications


  • Current Good Manufacturing Practices (cGMP)
  • NSF-Certified products available
  • A1 rating from Australia’s ultra-strict Therapeutic Goods Administration (TGA)
  • Their manufacturing facility, warehouses, and shipping centers are regularly inspected and have passed every inspection without the issuance of an FDA Form 483

Other notes:

  • Thorne produces ecologically and culturally responsible products
  • They have over 40 products in clinical trials around the world
Visit Store

Best Value: Life Extension

Supplement fans that want the highest quality without the cost of ultra-premium products have found their company. A consumer favorite, Life Extension’s behind-the-scenes access to modern research ahead of the general public helps them get effective, tested products to you quickly. I use Life Extension often.

Ingredients: Raw, pure, and potent. 99% of their products are manufactured in the U.S


  • A Certificate of Analysis (COA) is available for every product they produce
  • Voluntarily undergo Third-party ConsumerLab testing
  • International Fish Oil Standards (IFOS™) testing
  • Extensive internal testing of both active ingredient and potential contaminants


  • Non-GMO certified
  • Current Good Manufacturing Practices (cGMP)

Other notes:

  • You can request the COA of any product to verify its safety
  • A #1 pick on ConsumerLab’s 2020 customer satisfaction report
  • Life Extension offers complimentary health counsel and guides to treating a number of conditions
  • A full year, no-hassle return policy
  • They have a Super Sale every November with the best deals of the year. I like to stock up then
Save $5 on $50 & Get Free Shipping

Best Variety: Jarrow


Often my second choice behind Life Extension, Jarrow offers cutting-edge formulations in line with the latest research. Their decades of stellar industry reputation help me get past my initial concern of not finding specific ingredient sourcing information online.

Ingredients: I could not find much information about their ingredients online.


  • Raw materials and finished products both tested for contaminants of any kind
  • Products tested to confirm label accuracy and safety


  • Quality Assurance International (QAI)
  • Current Good Manufacturing Practices (cGMP)
  • USDA organic
  • California Department of Public Health Organic Processed Product
  • Non-GMO
  • Certified Kosher

Other notes:

  • Jarrow products have won dozens of industry awards over the last two decades
  • Their staff of scientists and health professionals are actively involved in clinical studies and continually work with researchers from universities and institutes around the world
  • One of the more established brands, Jarrow has produced supplements for nearly 43 years
  • They fund research studies on many of their products
Visit Store

Best Deals: Swanson


51 years on the market, Swanson is one of the oldest names in the industry. For those looking to get into supplements affordably, Swanson offers some of the best promos. Search just about any grocery store carrying supplements and Swanson products will turn up.

Ingredients: I could not find much information about their ingredients online. I did see some fillers in their products.


  • Ingredients are tested for purity and potency at multiple stages throughout the production process
  • Voluntarily undergo Third-party ConsumerLab testing


  • Current Good Manufacturing Practices (cGMP) since 2001

Other notes:

  • Swanson offers an “Absolute Satisfaction, 30-Day 100% Money-Back Guarantee”
  • They produce products in tailored quantities to reduce storage time, ensuring your supplements haven’t degraded by the time you use them
Visit Store

Premium Choice: Pure Encapsulations


As their name implies, you go to Pure Encapsulations (PE) for their extreme attention to both safety and quality. You know exactly what you get from Pure products. Your doctor will need to refer you, and prepare to pay a premium. If you have lots of allergies, sensitivities, or concern over quality look no further.

Ingredients: No fillers of any kind. Raw materials are sourced from the U.S., France, Japan, Switzerland, Germany and Italy. Hypoallergenic.


  • Certified independent laboratories test raw materials and finished products


  • Non-GMO certified
  • Exceeds the standards of the United States Pharmacopeia (USP).
  • Current Good Manufacturing Practices (cGMP)

Other notes:

  • Their open plant policy allows you to visit their facilities at any time and without notice
  • PE rigorously evaluates raw ingredient suppliers
  • Labels include the composition of the raw material, and true elemental weight of minerals
Visit Store

Best Herbs: Gaia Herbs

gaia herbs

Gaia brings 33 years to producing quality herbal supplements the right way. The herbal industry is rife with contamination. Not Gaia. From biodynamic compost to advanced regenerative farming practices, you can feel safe knowing their herbs are among the most nutritionally dense options available. Their website provides complete transparency into Gaia practices.

Ingredients: Gaia grows and tests their own ingredients.


  • Rigorous in-house testing for contaminants
  • DNA testing to verify that what you read on the label is what you will find in the bottle


  • Certified Organic through Oregon Tilth — one of the nation’s most stringent organic certifiers
  • Current Good Manufacturing Practices (cGMP)

Other notes:

  • An active partner of 11 herbal organizations
  • I love their handy herb reference guide to give you background on every plant
  • Their patented technology increases the absorption of concentrated plant extracts.
  • Gaia cares about people and the planet. They have all kinds of other certifications: Certified B Corp, Certified Monarch Waystation, Certified United Plant Savers Botanical Sanctuary
  • They have a strong commitment to sustainability
Visit Store

Practitioner Favorite: Standard Process

standardprocess logo

Standard Process understands that whole-foods supplements are only as good as the soil quality and inputs that go into producing the raw ingredients. They vertically integrate and rigorously test each batch of products for purity, safety, and consistency. Standard Process goes the extra mile to actually work with practitioners and ensure that their patients get results. For over 90 years, they’ve been deeply committed to sustainability, transparent manufacturing, nutrition research, and organic whole foods.

“Whole foods are the best natural source of vitamins. The key to the highest quality is the manufacturing process.” – Dr. Royal Lee, founder of Standard Process Share on X

Ingredients: Standard Process grows their ingredients in the rich soil of their organic farm. All ingredients undergo testing.


  • In-house active ingredient testing
  • FTIR, HPTLC, HPLC, and wet chemistry testing
  • Raw materials and finished product quality testing


  • Certified Organic
  • Regenerative Farming
  • Current Good Manufacturing Practices (cGMP)
  • Green Tier

Other notes:

  • Preserves delicate nutrients for maximum natural potency and efficacy.
  • Uses whole foods-based ingredients whenever possible.
  • Nutrition Innovation Campus sponsors the latest nutrition research
  • Plants are harvested less than two miles from their production facility
  • Extreme environmental responsibility
Visit Store

Also Great: Designs for Health

designsforhealth logo

Designs for Health has been a source trusted by healthcare professionals since 1989. From their leadership team to the formulation scientists they have extensive experience producing ultra-high-quality supplements. They commit to putting science first. Designs for Health has a massive catalog of supplements for virtually any need.

Ingredients:Designs for Health ingredients are sourced from select heavily-scrutinized vendors,


  • Raw materials testing
  • Finished product testing
  • Testing throughout manufacturing for ingredient identity, purity, quality, strength, and composition


  • Good Manufacturing Practices (GMP)
  • NPA
  • NSF
  • TGA
Visit Store

There are lots of other great supplement brands and manufacturers. These are the ones I have the most experience with.

How To Verify Supplement Quality

No matter what company you choose, give their products a thorough evaluation. There are a few criteria that all quality supplement companies have in common.

Quality Control Certification

Manufacturers should test the raw ingredients before they produce their formulation. Look for a third-party inspection certification. The best common supplement certifications include USP and NSF.

Certain products like fish oil have their own certifications. In the case of fish oil, look for IFOS.

Reputable companies will often provide you with Certificates of Analysis (CoAs) of their final product when asked.

Check The Ingredients Label

Capsule and pill fillers can unnecessarily interfere with absorption, and cause reactions in sensitive individuals. High-quality products minimize or do not contain “inactive ingredients”.

Passes Third Party Testing

Labdoor and ConsumerLab both independently test products for purity and safety. They purchase the supplements themselves and run unbiased testing.

ConsumerLab subscribers can access thousands of reports but they also publish some for free. Labdoor, on the other hand, publicizes its rankings of products across 36 supplement categories.

You can find the two here:

  • ConsumerLab
  • Labdoor

Which Supplement Brand Will You Choose Next?

Brands change fast in the supplement world, which is why I prefer the ones with a long, proven track record. Their products have stood the test of time and have raving fans.

The more products you add, the more opportunity for contamination. Choosing from the above quality brands reduces that risk so you don’t have to worry.

What do you think? Who do you like for supplements?


Post Tags: Recommendations, Supplements

2 thoughts on “7 Top Trustworthy Supplement Brands (That You Should Use)”

  1. I have been using Extend-Life Total Balance Unisex for several years and am completely satisfied with the
    results. I am 84 and in good health, partly, maybe, due to this supplement. I am an engineer by education
    and am a skeptic.
    Mostly, I believe my good health is due to working out hard with weights for the last 60+ years…no
    “muscle toning”, fairly good diet and sound sleep.
    What do you think?


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