Finding the best biohacking supplements is overwhelming. Thousands of brands make bold claims, yet most use cheap fillers, underdosed ingredients, or proprietary blends that hide what you are actually getting. I have spent years testing health optimization supplements firsthand — tracking biomarkers, monitoring subjective effects, and comparing formulations — so you do not have to wade through the noise.
This collection features my top-rated supplements for cognitive performance, energy, recovery, longevity, and overall vitality. Every product here meets strict criteria: third-party testing, bioavailable forms, transparent labeling, and ingredients backed by peer-reviewed research. From nootropic supplements that sharpen focus to adaptogens that build resilience, these are the formulations I actually use and recommend as a Certified Personal Trainer who works with high performers.
Many of these brands offer exclusive Outliyr discount codes, saving you anywhere from 10 to 20 percent off retail. Browse the full lineup below to find the right supplement stack for your goals.
Supplements Comparison
| Product | Best For | Price | Discount | Rating | |
|---|---|---|---|---|---|
| 5-Amino-1MQ | a cutting-edge compound targeting fat metabolism and cellular energy | URBAN14.8% off | ★★★½☆ | Get Deal | |
| 9-Me-BC | potent dopaminergic support for motivation and focus | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Ease Magnesium | You experience muscle cramps, soreness, or tension and want targeted relief | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Oceans Alive | Activation Products' flagship phytoplankton blend | URBAN15% off | ★★★½☆ | Get Deal | |
| Adapt Naturals Bio-Avail Colostrum+ | Readers wanting colostrum plus added lactoferrin and beta-glucan | — | — | — | Get Best Price |
| Amino Co EAAs | to support muscle recovery and protein synthesis | URBAN30.7% off | ★★★★☆ | Get Deal | |
| ARMRA Colostrum Health Revival | Readers who want the most established consumer colostrum brand | — | — | Get Best Price | |
| ARMRA Colostrum Performance Revival | Athletes seeking colostrum plus workout-recovery ingredients | — | — | Get Best Price | |
| Auro Wellness Glutaryl | Readers who prefer a topical glutathione spray | URBAN10% off | — | Get Deal | |
| AX3 Bio-Pure Astaxanthin | Anyone wanting a research-backed astaxanthin with proven bioavailability, esp… | URBAN20% off | ★★★★☆ | Get Deal | |
| BIOptimizers Berberine Breakthrough | Nick’s top overall berberine formula | URBAN10% off | ★★★½☆ | Get Deal | |
| BiOptimizers Magnesium Breakthrough | comprehensive magnesium support from multiple forms | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers MassZymes | You experience bloating, gas, or discomfort after meals | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers Probiotic Breakthrough (formerly P3-OM) | — | URBAN10% off | ★★★★½ | Get Deal | |
| Black Lotus Shilajit | a mineral-rich daily supplement with fulvic acid | URBAN15% off | ★★★★☆ | Get Deal | |
| Bloom Nutrition Colostrum + Collagen | Readers prioritizing convenience over specialized full-dose products | — | — | — | Get Best Price |
| Blue Cannatine | targeted nutritional support for your specific health goals | URBAN10% off | ★★★★☆ | Get Deal | |
| Blue Sky Peptides | Budget buyers who prioritize low prices and frequent deals, and are comfortab… | $39.95 | — | ★★½☆☆ | Get Best Price |
| BodyBio E-Lyte | high-potassium electrolytes | URBAN15% off | ★★★★☆ | Get Deal | |
| BodyBio Liposomal Glutathione | a premium liposomal glutathione from a trusted brand | URBAN15.5% off | — | Get Deal | |
| Botanabolic | multi-mechanism testosterone optimization with botanical androgens | URBAN14.8% off | ★★★★☆ | Get Deal | |
| C8 MCT Oil | targeted nutritional support for your specific health goals | URBAN27.8% off | ★★★★☆ | Get Deal | |
| Chemyo | SARMs researchers who prioritize verified purity, transparent testing, and a … | $59.99 | — | — | Get Best Price |
| Codeage Liposomal Urolithin A | Readers seeking a multi-ingredient Urolithin A formula with added mitochondri… | URBAN10% off | — | Get Deal | |
| CollaGenius | cognitive support combined with beauty and anti-aging benefits | URBAN7.6% off | ★★★½☆ | Get Deal | |
| Core Peptides | Researchers who value fast shipping and custom blend options, but proceed wit… | $47 | — | ★★★★☆ | Get Best Price |
| Cortisol Balance | targeted cortisol management with clinically studied ingredients | $60 | — | ★★★★☆ | Get Best Price |
| Cosmic Nootropic | International readers seeking rare pharmaceutical nootropics | URBAN55% off | — | Get Deal | |
| Cowboy Colostrum Nature's Gold | Readers wanting a straightforward first-milking colostrum with flavor options | — | — | — | Get Best Price |
| Crevolution | creatine, GAA and TMG in one unflavored scoop | URBAN15% off | — | Get Deal | |
| D3K2 ReSet | D3 and K2 in proper ratio from a trusted brand | URBAN10% off | — | Get Deal | |
| Do Not Age Spermidine | Longevity enthusiasts who want to support autophagy and cellular renewal thro… | $39 | — | ★★★½☆ | Get Best Price |
| DoNotAge Pure NR | International buyers seeking a high-dose bulk NR capsule | — | — | — | Get Best Price |
| Double Wood Berberine | an affordable 500 mg berberine HCl capsule | $19.95 | — | ★★★★☆ | Get Best Price |
| Double Wood Resveratrol | Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol … | $19.95 | — | ★★★½☆ | Get Best Price |
| Double Wood Spermidine | Those who want a high-dose pure spermidine supplement at a competitive price … | $39.95 | — | ★★★★☆ | Get Best Price |
| Dream Optimizer | Readers who want a fast, convenient spray for occasional nighttime wakeups | URBAN15% off | — | Get Deal | |
| Earth Circle Organics Chlorella | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina + Chlorella | a whole-food plant-based source of vitamins, minerals, and protein | NICKURBAN20% off | ★★★★☆ | Get Deal | |
| Ergothioneine | targeted nutritional support for your specific health goals | — | ★★★½☆ | Get Best Price | |
| Essential C Complex | — | — | — | Get Best Price | |
| Folqs First-Day Milking Bovine Colostrum | to strengthen your gut lining and immune defenses naturally | URBAN10% off | ★★★★☆ | Get Deal | |
| Healthgevity bioREPAIR | Readers wanting a targeted capsule formula for gut-barrier support | URBAN10% off | — | Get Deal | |
| Healthgevity IGNITE+ | metabolic support for glucose regulation and body composition | URBAN10% off | ★★★½☆ | Get Deal | |
| Healthgevity Rejuvenate 2.0 | Serious longevity enthusiasts who want a comprehensive multi-pathway senolyti… | $124.99 | — | ★★★★½ | Get Best Price |
| Hergevity Balance | hormone support through estrogen receptor-beta signaling without direct hormo… | URBAN9.3% off | ★★★★☆ | Get Deal | |
| HighStreetPharma | Readers who already have appropriate medical guidance and seek established ge… | $30 | — | — | Get Best Price |
| InfiniFiber | broad prebiotic fiber diversity plus a probiotic in a single scoop | $54.99 | — | ★★★★½ | Get Best Price |
| Infiniwell Senolytic | Budget-conscious biohackers wanting a proven senolytic formula without premiu… | $69.95 | — | ★★★★☆ | Get Best Price |
Showing 48 of 140 products in Supplements
Transparent Labs Formulas
Transparent Labs
- Best for
- You want clean supplements with fully transparent ingredient labels
- Skip if
- You're extremely sensitive to stimulants (some products are high-stim)
$49.99
Get Best Price
Black Lotus Shilajit
Black Lotus
- Best for
- You want a mineral-rich daily supplement with fulvic acid
- Skip if
- You can't handle a strong earthy/tar-like taste
URBAN — 15% off
Natural & Potent GLP-1 Pills
Calocurb
- Best for
- You want natural GLP-1 support without prescription medications
- Skip if
- You're already on prescription GLP-1 agonists (discuss with your doctor)
Details checked 11/15/2025
URBAN — 10% off
Amino Co EAAs
Amino Co
- Best for
- You want to support muscle recovery and protein synthesis
- Skip if
- You already consume adequate protein from whole food sources
Details checked 11/17/2025
URBAN — 30.7% off
BiOptimizers MassZymes
BiOptimizers
- Best for
- You experience bloating, gas, or discomfort after meals
- Skip if
- You digest food well without any issues
Details checked 06/03/2026
URBAN — 10% off
Paleovalley Snacks & Supplements
Paleovalley
- Best for
- You want clean, grass-fed meat snacks without harmful additives
- Skip if
- You're vegetarian or vegan
Details checked 11/26/2025
Nootopia Brain Enhancing Supplements
Nootopia
- Best for
- You want personalized nootropic blends tailored to your brain chemistry
- Skip if
- You prefer simple, single-ingredient supplements
Details checked 11/26/2025
URBAN — 10% off
BodyBio E-Lyte
BodyBio
- Best for
- You need high-potassium electrolytes
- Skip if
- You sweat heavily and need high sodium
URBAN — 15% off
NutriGenesis Multi for Women
Performance Lab
- Best for
- The foundation-first buyer who wants to fix deficiencies before chasing symptoms
- Skip if
- You expect direct relief for hot flashes or night sweats; this is the base layer, not the symptom fix
Details checked 09/18/2026
$49
Get Best Price
Spartan Formula
Lost Empire Herbs
- Best for
- You want a broad-spectrum adaptogen blend for athletic performance and endurance
- Skip if
- You want exact milligram doses listed for each ingredient
Details checked 02/10/2026
URBAN — 20% off
Life Extension Senolytic Activator
Life Extension
- Best for
- Budget-conscious users who want a simple, affordable senolytic from a trusted brand
- Skip if
- You want a comprehensive multi-pathway senolytic formula
$24
Get Best Price
Infiniwell Senolytic
Infiniwell
- Best for
- Budget-conscious biohackers wanting a proven senolytic formula without premium pricing
- Skip if
- You want a comprehensive multi-pathway senolytic with branded ingredients and full dose transparency
$69.95
Get Best Price
Primeadine Original Spermidine
Primeadine
- Best for
- Longevity-focused individuals who want a research-backed autophagy activator from whole-food sources rather than synthetic spermidine.
- Skip if
- You're on a tight supplement budget, have wheat/gluten sensitivity (unless buying the GF version), or prefer single-capsule dosing.
$90
Get Best Price
Double Wood Berberine
Double Wood
- Best for
- You want an affordable 500 mg berberine HCl capsule
- Skip if
- You want a dihydroberberine or liposomal formula
Details checked 06/08/2026
$19.95
Get Best Price
Stress Guardian
BiOptimizers
- Best for
- You want to enhance focus, memory, or mental clarity
- Skip if
- You haven't optimized sleep and nutrition first (start there)
Details checked 11/07/2025
URBAN — 10% off
Mind Lab Pro
Performance Lab (Mind Lab Pro)
- Best for
- You want a clean, stimulant-free nootropic for daily use
- Skip if
- You're an experienced biohacker wanting cutting-edge compounds
Details checked 11/13/2025
$69
Get Best Price
C8 MCT Oil
Kiss My Keto MCT
- Best for
- You want targeted nutritional support for your specific health goals
- Skip if
- You haven't optimized diet, sleep, and exercise first (they matter more)
Details checked 11/15/2025
URBAN — 27.8% off
SLEEPgevity
Healthgevity
- Best for
- You want melatonin-free sleep support that works through cortisol modulation
- Skip if
- You already sleep well and wake refreshed
Details checked 02/10/2026
URBAN — 10% off
RnA ReSet ReMag
RnA ReSet
- Best for
- You want a highly absorbable liquid magnesium without laxative effects
- Skip if
- You're on a tight supplement budget and need basic magnesium
Details checked 03/29/2026
URBAN — 10% off
Core Peptides
Core Peptides
- Best for
- Researchers who value fast shipping and custom blend options, but proceed with caution.
- Skip if
- You want proven reliability or are placing large orders.
$47
Get Best Price
VITALITYbits
ENERGYbits
- Best for
- You want a convenient whole-food micronutrient source for travel
- Skip if
- You can't stand the taste of algae (even swallowed, there's a hint)
Details checked 06/09/2026
NICKURBAN — 20% off
Folqs First-Day Milking Bovine Colostrum
Folqs
- Best for
- You want to strengthen your gut lining and immune defenses naturally
- Skip if
- You have a dairy allergy (it's bovine-derived)
Details checked 06/09/2026
URBAN — 10% off
Limitless Biotech
Limitless Biotech
- Best for
- Researchers who want the broadest peptide catalog with verified purity and don't mind paying a premium for quality.
- Skip if
- You're on a tight budget or need international delivery within a week.
Details checked 06/09/2026
URBAN — 23.1% off