Finding the best biohacking supplements is overwhelming. Thousands of brands make bold claims, yet most use cheap fillers, underdosed ingredients, or proprietary blends that hide what you are actually getting. I have spent years testing health optimization supplements firsthand — tracking biomarkers, monitoring subjective effects, and comparing formulations — so you do not have to wade through the noise.
This collection features my top-rated supplements for cognitive performance, energy, recovery, longevity, and overall vitality. Every product here meets strict criteria: third-party testing, bioavailable forms, transparent labeling, and ingredients backed by peer-reviewed research. From nootropic supplements that sharpen focus to adaptogens that build resilience, these are the formulations I actually use and recommend as a Certified Personal Trainer who works with high performers.
Many of these brands offer exclusive Outliyr discount codes, saving you anywhere from 10 to 20 percent off retail. Browse the full lineup below to find the right supplement stack for your goals.
Supplements Comparison
| Product | Best For | Price | Discount | Rating | |
|---|---|---|---|---|---|
| 5-Amino-1MQ | a cutting-edge compound targeting fat metabolism and cellular energy | URBAN14.8% off | ★★★½☆ | Get Deal | |
| 9-Me-BC | potent dopaminergic support for motivation and focus | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Ease Magnesium | You experience muscle cramps, soreness, or tension and want targeted relief | URBAN15% off | ★★★★☆ | Get Deal | |
| Activation Products Oceans Alive | Activation Products' flagship phytoplankton blend | URBAN15% off | ★★★½☆ | Get Deal | |
| Adapt Naturals Bio-Avail Colostrum+ | Readers wanting colostrum plus added lactoferrin and beta-glucan | — | — | — | Get Best Price |
| Amino Co EAAs | to support muscle recovery and protein synthesis | URBAN30.7% off | ★★★★☆ | Get Deal | |
| ARMRA Colostrum Health Revival | Readers who want the most established consumer colostrum brand | — | — | Get Best Price | |
| ARMRA Colostrum Performance Revival | Athletes seeking colostrum plus workout-recovery ingredients | — | — | Get Best Price | |
| Auro Wellness Glutaryl | Readers who prefer a topical glutathione spray | URBAN10% off | — | Get Deal | |
| AX3 Bio-Pure Astaxanthin | Anyone wanting a research-backed astaxanthin with proven bioavailability, esp… | URBAN20% off | ★★★★☆ | Get Deal | |
| BIOptimizers Berberine Breakthrough | Nick’s top overall berberine formula | URBAN10% off | ★★★½☆ | Get Deal | |
| BiOptimizers Magnesium Breakthrough | comprehensive magnesium support from multiple forms | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers MassZymes | You experience bloating, gas, or discomfort after meals | URBAN10% off | ★★★★☆ | Get Deal | |
| BiOptimizers Probiotic Breakthrough (formerly P3-OM) | — | URBAN10% off | ★★★★½ | Get Deal | |
| Black Lotus Shilajit | a mineral-rich daily supplement with fulvic acid | URBAN15% off | ★★★★☆ | Get Deal | |
| Bloom Nutrition Colostrum + Collagen | Readers prioritizing convenience over specialized full-dose products | — | — | — | Get Best Price |
| Blue Cannatine | targeted nutritional support for your specific health goals | URBAN10% off | ★★★★☆ | Get Deal | |
| Blue Sky Peptides | Budget buyers who prioritize low prices and frequent deals, and are comfortab… | $39.95 | — | ★★½☆☆ | Get Best Price |
| BodyBio E-Lyte | high-potassium electrolytes | URBAN15% off | ★★★★☆ | Get Deal | |
| BodyBio Liposomal Glutathione | a premium liposomal glutathione from a trusted brand | URBAN15.5% off | — | Get Deal | |
| Botanabolic | multi-mechanism testosterone optimization with botanical androgens | URBAN14.8% off | ★★★★☆ | Get Deal | |
| C8 MCT Oil | targeted nutritional support for your specific health goals | URBAN27.8% off | ★★★★☆ | Get Deal | |
| Chemyo | SARMs researchers who prioritize verified purity, transparent testing, and a … | $59.99 | — | — | Get Best Price |
| Codeage Liposomal Urolithin A | Readers seeking a multi-ingredient Urolithin A formula with added mitochondri… | URBAN10% off | — | Get Deal | |
| CollaGenius | cognitive support combined with beauty and anti-aging benefits | URBAN7.6% off | ★★★½☆ | Get Deal | |
| Core Peptides | Researchers who value fast shipping and custom blend options, but proceed wit… | $47 | — | ★★★★☆ | Get Best Price |
| Cortisol Balance | targeted cortisol management with clinically studied ingredients | $60 | — | ★★★★☆ | Get Best Price |
| Cosmic Nootropic | International readers seeking rare pharmaceutical nootropics | URBAN55% off | — | Get Deal | |
| Cowboy Colostrum Nature's Gold | Readers wanting a straightforward first-milking colostrum with flavor options | — | — | — | Get Best Price |
| Crevolution | creatine, GAA and TMG in one unflavored scoop | URBAN15% off | — | Get Deal | |
| D3K2 ReSet | D3 and K2 in proper ratio from a trusted brand | URBAN10% off | — | Get Deal | |
| Do Not Age Spermidine | Longevity enthusiasts who want to support autophagy and cellular renewal thro… | $39 | — | ★★★½☆ | Get Best Price |
| DoNotAge Pure NR | International buyers seeking a high-dose bulk NR capsule | — | — | — | Get Best Price |
| Double Wood Berberine | an affordable 500 mg berberine HCl capsule | $19.95 | — | ★★★★☆ | Get Best Price |
| Double Wood Resveratrol | Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol … | $19.95 | — | ★★★½☆ | Get Best Price |
| Double Wood Spermidine | Those who want a high-dose pure spermidine supplement at a competitive price … | $39.95 | — | ★★★★☆ | Get Best Price |
| Dream Optimizer | Readers who want a fast, convenient spray for occasional nighttime wakeups | URBAN15% off | — | Get Deal | |
| Earth Circle Organics Chlorella | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina | Readers seeking a straightforward algae supplement in this format | — | — | — | Get Best Price |
| ENERGYbits Spirulina + Chlorella | a whole-food plant-based source of vitamins, minerals, and protein | NICKURBAN20% off | ★★★★☆ | Get Deal | |
| Ergothioneine | targeted nutritional support for your specific health goals | — | ★★★½☆ | Get Best Price | |
| Essential C Complex | — | — | — | Get Best Price | |
| Folqs First-Day Milking Bovine Colostrum | to strengthen your gut lining and immune defenses naturally | URBAN10% off | ★★★★☆ | Get Deal | |
| Healthgevity bioREPAIR | Readers wanting a targeted capsule formula for gut-barrier support | URBAN10% off | — | Get Deal | |
| Healthgevity IGNITE+ | metabolic support for glucose regulation and body composition | URBAN10% off | ★★★½☆ | Get Deal | |
| Healthgevity Rejuvenate 2.0 | Serious longevity enthusiasts who want a comprehensive multi-pathway senolyti… | $124.99 | — | ★★★★½ | Get Best Price |
| Hergevity Balance | hormone support through estrogen receptor-beta signaling without direct hormo… | URBAN9.3% off | ★★★★☆ | Get Deal | |
| HighStreetPharma | Readers who already have appropriate medical guidance and seek established ge… | $30 | — | — | Get Best Price |
| InfiniFiber | broad prebiotic fiber diversity plus a probiotic in a single scoop | $54.99 | — | ★★★★½ | Get Best Price |
| Infiniwell Senolytic | Budget-conscious biohackers wanting a proven senolytic formula without premiu… | $69.95 | — | ★★★★☆ | Get Best Price |
Showing 72 of 140 products in Supplements
Ojai Energetics Full Spectrum Hemp Elixir
Ojai Energetics
- Best for
- You want fast-acting, water-soluble CBD/hemp extract
- Skip if
- You're subject to drug testing (full-spectrum hemp contains trace THC)
Details checked 11/25/2025
$74.95
Get Best Price
BiOptimizers Magnesium Breakthrough
BiOptimizers
- Best for
- You want comprehensive magnesium support from multiple forms
- Skip if
- You already supplement with a high-quality magnesium product
Details checked 11/28/2025
URBAN — 10% off
ENERGYbits Spirulina + Chlorella
ENERGYbits
- Best for
- You want a whole-food plant-based source of vitamins, minerals, and protein
- Skip if
- You dislike the taste of algae (even in tablet form, burps happen)
Details checked 11/05/2025
NICKURBAN — 20% off
Thesis Nootropics
Thesis
- Best for
- You want personalized nootropic blends based on testing 127+ ingredients
- Skip if
- You already know which individual nootropic ingredients work for you
Details checked 11/17/2025
URBAN — 15% off
Best MCT OilLevelUp Clean C8 MCT Oil
LevelUp
- Best for
- Coffee and smoothie addition
- Skip if
- Need rapid ketone elevation
Details checked 03/03/2026
$25
Buy LevelUp C8 MCT
Activation Products Ease Magnesium
Activation Products
- Best for
- You experience muscle cramps, soreness, or tension and want targeted relief
- Skip if
- You prefer the convenience of oral capsules or powders
URBAN — 15% off
Double Wood Spermidine
Double Wood
- Best for
- Those who want a high-dose pure spermidine supplement at a competitive price point to support autophagy and cellular maintenance without the bulk of wheat germ extract capsules.
- Skip if
- You prefer whole-food-derived supplements over synthetic isolates, or you want to wait for stronger human clinical evidence before adding spermidine to your stack.
$39.95
Get Best Price
ZeoCharge Zeolite
Zeolite Labs
- Best for
- You want a simple daily detox support for heavy metal exposure
- Skip if
- You're expecting dramatic overnight detox results
URBAN — 10% off
Thorne Biological Age Test
Thorne
- Best for
- You want pharmaceutical-grade supplements from a trusted, clinician-recommended brand
- Skip if
- You prefer budget-friendly supplement brands
Details checked 11/21/2025
MitoZen Sandman (Glutathione & Melatonin)
Mitozen
- Best for
- You struggle with falling or staying asleep
- Skip if
- You sleep well without supplementation
Details checked 11/05/2025
URBAN — 5% off
Lost Empire Herbs
Lost Empire Herbs
- Best for
- You want hard-to-find adaptogenic herbs in tincture form
- Skip if
- You can't handle the intense taste of herbal tinctures
Details checked 02/21/2026
URBAN — 20% off
Do Not Age Spermidine
Do Not Age
- Best for
- Longevity enthusiasts who want to support autophagy and cellular renewal through a dedicated high-purity spermidine supplement from a reputable brand.
- Skip if
- You prefer to get spermidine from whole foods like aged cheese and wheat germ, or you want supplements with robust human clinical trial evidence before investing.
$39
Get Best Price
Organifi Collagen
Organifi
- Best for
- You want an affordable multi-type collagen for skin, hair, and joint health
- Skip if
- You follow a vegan or vegetarian diet
URBAN — 15% off
UltraKanna
UltraKanna
- Best for
- You want a fast-acting natural mood lift for social situations
- Skip if
- You're taking SSRIs or other serotonin-affecting medications
URBAN — 10% (on first order) off
5-Amino-1MQ
Limitless Biotech
- Best for
- You want a cutting-edge compound targeting fat metabolism and cellular energy
- Skip if
- You're new to advanced supplementation (research thoroughly first)
Details checked 10/31/2025
URBAN — 14.8% off
CollaGenius
Nootopia
- Best for
- You want cognitive support combined with beauty and anti-aging benefits
- Skip if
- You're vegan (contains collagen from animal sources)
Details checked 11/24/2025
URBAN — 7.6% off
Natural Stacks Brain Performance Supplements
Natural Stacks
- Best for
- You want transparent, open-source nootropic formulas
- Skip if
- You want an all-in-one nootropic solution
Details checked 11/26/2025
URBAN — 15% off
Double Wood Resveratrol
Double Wood
- Best for
- Budget-conscious longevity enthusiasts who want a reliable trans-resveratrol supplement for cardiovascular and anti-aging support without paying premium brand prices.
- Skip if
- You want maximum bioavailability and prefer micronized or liposomal resveratrol formulations, or you're taking blood thinners since resveratrol may enhance anticoagulant effects.
Details checked 06/09/2026
$19.95
Get Best Price
Healthgevity IGNITE+
Healthgevity
- Best for
- You want metabolic support for glucose regulation and body composition
- Skip if
- You already take berberine or similar glucose-support compounds
Details checked 03/29/2026
URBAN — 10% off
Ultimate (Delicious) Meal Replacement
Keto Brick
- Best for
- You need a quick, nutritionally complete meal when time is tight
- Skip if
- You prefer and have time for whole food meals
Details checked 11/13/2025
$12
Get Best Price
Innerbody Labs Testosterone Support
Innerbody Labs
- Best for
- You want a natural T-booster with clinically studied ingredients
- Skip if
- You expect pharmaceutical-level testosterone results
URBAN — 10% off
Activation Products Oceans Alive
Activation Products
- Best for
- You want Activation Products' flagship phytoplankton blend
- Skip if
- You're sensitive to strong algae/ocean flavors
Details checked 02/21/2026
URBAN — 15% off
Silver Biotics
Silver Biotics
- Best for
- You want a natural antimicrobial for immune support
- Skip if
- You're pregnant or nursing
Details checked 11/10/2025
URBAN — 30% off