Energy-Boosting Formula of Peak Athletes Revealed (Mimic Exercise, All-In-One Longevity Stacks, & The Ultimate Pre-Workout)

Nick Urban [00:00:07]:
Are you a high performer, obsessed with growth, and looking for an edge? Welcome to MINDBODY Peak Performance. Together, we’ll discover underground secrets to unlocking the full potential of your mind, body, and spirit. We’ll learn from some of the world’s leading minds, from ancient wisdom to cutting edge tools and everything in between. This is your host, Nick Urban. Enjoy the episode. What if your pre workout supplement is quietly sabotaging your gains? Many formulas spike your system with banned substances and cheap inferior forms of vitamins that can disrupt your neurotransmitters, tax your adrenals, and work against your long term health. Kyle VanderLeest joins us to unpack what’s really in your pre workout and why certain ingredients like pyridoxine hydrochloride can sabotage your progress and how you can upgrade your stack with smarter bioharmonized compounds that energize you without wrecking your system. But if pre workout supplements aren’t your thing, don’t worry.

Nick Urban [00:01:19]:
We cover a lot of other ground in this episode, such as a class of exercise mimicking ingredients called exercise mimetics, powerful small molecules like five amino one m q as well as the recently popular SLU p p three three two. We talk about t two and the peptide epitalon as well as a satiety and weight loss peptide called DNF ten. All that and a whole lot more with our guest this week. He is Kyle VanderLeest, a nutritionist, naturopath, and functional health coach turned supplement formulator behind the company LevelUp Health, and I have used a bunch of their different products. I have their Total Recomp formula in front of me, their methylene blue product, their testosterone optimizer, their peptide based nootropic, and their longevity formula. My personal favorites, as I mentioned in the episode, are their total recomp, which is the exercise and the pill formula, as well as their pre workout, which doubles as a nootropic, and it has a solid formula. I don’t usually use pre workouts, but this is the exception. And in this episode, you’ll understand why.

Nick Urban [00:02:32]:
If you wanna try their products, you can use the code urban on leveluphealth.com, or you can click the link in the show notes, which will be at outlier.com, 0 u t l I y r, Com / the number 209. And if you wanna revisit last week’s episode to catch the first part about how to formulate properly, You can find that at outlier.com, 0 u t l I y r, Com / the number 200andeight. These formulas are a bit pricey, but once you use them, you feel them, you turn the bottle around, and you look at the dosages of the star ingredients, you’ll understand why. So use the code urban to save 15%. Now on to the interview with Kyle. Kyle, welcome back to the show. The episode last week, we discussed your approach to formulations and how people can figure out what exactly is gonna work for them. And today, I wanna discuss some of the things that I’ve used that have worked for me.

Nick Urban [00:03:31]:
And before we get started, I wanna recap an email I got from you just the other day, and that was an email that said that your pre workout is robbing your gains. Why is that? Cortisol

Kyle VanderLeest [00:03:45]:
in short. And I guess a lot of pre workouts have terrible forms of vitamins. The ones that if they even use them to be fair, but forms, I really hate a pyridoxine hydrochloride, B6 HDL, not using P five P you are basically driving a B6 deficiency. It will bind, but not give you the effects of B6, in which that has a really significant impacts on your homocysteine levels, for example, on your neurotransmitters. B six is a is a key cofactor for neurotransmitter synthesis. So if you’re using HCL b six, get it out of there. The supplement industry needs to stop using that. It’s about 16 to 18 times cheaper than p five p.

Kyle VanderLeest [00:04:30]:
So that’s why it’s used. And for people who don’t know better or don’t care or, you know, that’s why it’s being used ubiquitously.

Nick Urban [00:04:37]:
Before we go into that, underscore you just said about vitamin b six, and that is one of the things I look at when I’m evaluating supplements in general. If I flip over the back panel, I look under the nutrition facts and I see that they use the inactive form of vitamin b six pronunciation I think is pyridoxine hydrochloride and they don’t use vitamin p five or they don’t use p the p five p form, then I will just put the product back down because it shows that they’re not even willing to use the high quality ingredients. And with the inactive form of vitamin b six, the potential toxicity, like the window to cause that is very low. I think it’s like twenty five milligrams a day or something or maybe it’s fifty. And a lot of products will have about that much in it and then you can’t get the actual the beneficial active form. And the symptoms aren’t always that severe in the short term, but they can be, like, very dangerous if you’re consuming this across multiple products over a long period of time.

Kyle VanderLeest [00:05:34]:
Yeah. It can impair the neurotransmitter levels. It can actually cause nerve damage. That’s peripheral neuropathy. That’s the big the big issue with it, like prolonged ting tingling in distal joints, numbness, burning sensation. So, like, it needs to be converted to active form, which then puts burden on methylation pathways too. It’s actually meant to support methylation and then use this form and then you’re hindering it or robbing methylation. So it’s ridiculous.

Kyle VanderLeest [00:06:00]:
And it just needs to be binned along with folic acid, acid, which is again, pretty much the same thing. Like it’s inactive, needs to be converted to, MTA, methylated folate for, for it to then work on, increasing Sammy and helping methylation. Like methylation is probably one of the, you know, we’ve been talking about it, you and I, for probably five years, but I think it’s now hitting the mainstream. People like Gary Breck who have really overemphasized the importance of it, but it’s still, like, very important. So is COMT and so is, like, supporting the hundreds of other enzymatic pathways in your body and every form of vitamin has the potential for you to supplement something synthetic. Like there’s like B1, for example, no issues, in my opinion, with this one, but there’s like tiers to it. There’s you can go for like a derivative, like TTFD or Benfofium and the fat soluble burden, fat soluble B1. And then there’s, like, three other forms of b one, which all have different bioavailability, different efficacy, and different levels of conversion that’s required for them then to be bioidentical to what your body uses.

Kyle VanderLeest [00:07:06]:
And I am bringing out a b vitamin that does not have a single form that is not bioidentical to what your body needs. So that’s one way that supplements in general are kind of robbing your health gains. But if you wanna leave B vitamins alone, we can leave nine and B12. I think they’re kind of done to death. B12 doesn’t necessarily hurt you. If you use cyanocobalamin, it just doesn’t mean you you’re just not going to absorb it and end up with a cyanide molecule. What are the other ones? Like, never mind. We’ll leave the b vitamins, but, yeah, the other way is just overstimulation of the adrenals.

Kyle VanderLeest [00:07:40]:
Like, a lot of preworkouts have so much caffeine or hordenine and dynamine and all these other, I’ve forgotten the term for a methylate met methylamines or something like that. And they directly increase cortisol and that’s a good thing for your workout gains. Like there’s no doubt caffeine is an ergogenic aid for workout performance, but if you are ramping your adrenals up to 11 every single morning or every single workout, then you will be depleting your minerals. You will be in, I guess, more of a catabolic state. Like, that is cortisol is, you know, not not good for your gain. So this is why I really like new ingredients like, paraxanthin. It will give you that mental stimulation, that dopamine effect, and you will feel more wired and more ready to do your workout without necessarily having to worry about your adrenals getting completely overburdened and overtaxed. There’s other ways that pre workouts aren’t doing things well.

Kyle VanderLeest [00:08:37]:
Like, they’ll use things like just arginine, like, a heap of arginine in in the product and think that gets absorbed when all it will do is just create a heap of vasodilation in your gut, but not actually get to your muscles. Things like l citrulline are a lot better. And but even then, like, you can overdose things like citrulline. Arginine and lysine kind of balance each other. And then if you are overdoing the pump ingredients, then you might end up, as a balanced perspective, low on lysine and be more predisposed to viral infections or getting sick. So everything, again, or the bell shaped curve, I’m I’m a a broken record talking about that, but that’s, really part of the reason why I don’t like the supplement industry too much. And they’ve always pushed short term gains over long term health and yeah, by using fake forms of vitamins by overtaxing the adrenals, and by not actually supporting leaving you worse off than when you began, I don’t ever like pre workouts for that purpose. The other thing, which I admit my product has piccolized.

Kyle VanderLeest [00:09:42]:
I really did not wanna use it, but I just had to get it out there. It took over a year and a half of development and tasted so bad because we actually used all of the doses of all of the adaptogens, all the active b vitamins and things like zirudine, monophosphate, paraxanthin. They all tasted so bad that we just put it out. And I don’t stand by my pre workout. Don’t buy it. I’m doing another one with natural flavors, but it would not rob your gains. It will only cause a bit of gut issues if you don’t do well with sucralose. But there are brands doing it right now, and we will be an an extra on one of those brands.

Kyle VanderLeest [00:10:17]:
But, yeah, it’s it’s a tricky industry to be a part of, and it’s kind of sad to see the ones that have, like, a hundred thousand units purchased that have, like, five hundred milligrams of caffeine and nothing to support your adrenal function or not, or, you know, just completely put people, you know, bring them up and then dump them back down on the other end. So

Nick Urban [00:10:38]:
Actually, I’m a big fan of your pre workout, and I did notice the other day that it had sucralose. I was kinda boned about that. But I looked at the formula in general, and what I love is that you really support a lot of different facets of performance starting with electrolytes. Like, that’s a big one for me and everyone, really. And you don’t just use, like, super salt based heavy electrolyte. You you use coconut water powder, which is a great source of, like, the more bioavailable natural form of electrolytes. Then you also add in some cool, fancier ingredients like, alpha ketoglutarate, and you support dopamine via paraxanthin, which is already more dopaminergic than, caffeine is. But then you also have some of the other precursors to dopamine like n acetyltyrosine, l tyrosine, nalt, and l tyrosine.

Nick Urban [00:11:25]:
But then you also have alpha GPC to further enhance acetylcholine and out like, power output. I think there’s research around that. You also got some adaptogens in there. You got uridine and the methylated form, the active form of the b vitamins. So to me, that’s a solid formula. I just add a little of my own essential amino acid powder in there, and I’m good to go. I’ll admit I’ve never actually used two scoops. I only used one scoop.

Nick Urban [00:11:51]:
So half of a serving, and I still feel like it’s jet fuel without, like, being too stimulated.

Kyle VanderLeest [00:11:56]:
I’m gonna take a step back. I’m very hard on myself and my formulas. And if sucralose in the smallest possible dose we can use is the worst thing in that formula, it’s not too bad. So I’ll I’ll take it back. There’s a lot of really good things in there that I can’t let the like, I think for the whole thing, less than a gram of sucralose ruined the whole 500 grams of of active. But, yeah, I just tried my best to make it really good. Balancing the stimulant effect with theanine and using tea accruing instead of caffeine, for example. That’s an another way.

Kyle VanderLeest [00:12:29]:
Like, that is a is a stimulant that’s not going to result in you developing tolerance, and it doesn’t bring you up to this 10 out of 10 energy level. It’s more of a subtle thing. And paraxanthin, I’ve never found that hits as hard as caffeine or something like dynamine, but it still gives you a good dopaminergic boost. It doesn’t elevate your blood pressure. It doesn’t, cause, you know, anxiety or anything like that, like the other ones may do. And tyrosine, I think, is fantastic. It’s not gonna be a workout aid, but it necessarily, but by increasing your motivation and, you know, your your desire to get your workout done, like, that’s fantastic too. And the coconut water powder is one of my favorite things to use.

Kyle VanderLeest [00:13:09]:
It’s a little bit carb y if people don’t want to necessarily have any sugars, but it’s just a really good way to deliver minerals as well as the next version we’re bringing out. We’re even bolstering it with sucrazole magnesium and getting, like electrolyte powder level, levels of, minerals added to it as well as completing the full spectrum of the b vitamins. For this one, it’s just b three six nine and twelve, which for the most part, do most of what you’d need for exercise performance and energy. But, you know, we wanted to make wanted to make a pre workout that, unlike what we mentioned earlier, that it takes from your gains. Well, this one leaves you better off than when you than, you, after using it than you did prior to taking it. So by increasing your electrolyte levels, licorice root, bacopa, urodine, these are all supporting your brain and your adrenals. Alpha GPC is super beneficial for focus, especially when combined with paraxanthin and tyrosine. Like, you’re gonna have a very significant pick me up mentally.

Kyle VanderLeest [00:14:06]:
Even if you don’t work out, like, there’s no obligation in taking this to work out. I take it sometimes and just go and do my work because I got extra motivation, and I feel better for having taken it. So whereas other ones, like, if you don’t use your workout, they might megadose beta alanine so you get the tingles, which doesn’t really help you feel good. And then, you know, the amount of caffeine, if you don’t use that, you know, workout, then you’ll pretty you’ll feel not particularly good. So Yeah. That’s from the rationale behind that product.

Nick Urban [00:14:36]:
Yeah. I also like that you added beta alanine because that’s good for endurance to help buffer, lactate. And then also you have Schizandra, which is another adaptogen in Bacopa. A lot of days when I will use this, I try and use it before afternoon, so I’m not stimulated into the evening. I’m kinda sensitive to some of these in some stimulating ingredients. But then I won’t even use any other nootropic throughout the day. It’ll be my pre workout and my nootropic all in one. Just from one scoop too.

Nick Urban [00:15:03]:
I’m curious how I’ll do with two scoops but this was a very pleasantly surprising pre workout because I used to take these very strong stimulating pre workouts before every workout many years ago, and I stopped. And it’s nice finding a product that actually has the right forms and the right ingredients and, like you said, leaves you better than you found it.

Kyle VanderLeest [00:15:22]:
Yeah. I mean, I’m a consumer of them. I like you like what you used to be until recently. When now you’re back to it, I do take pre workouts almost every time I do a a heavy lifting thing. I just love an ergogenic aid and like to take something as a ritual. So having that and so, honestly, it’s part of the reason why I make most of my products is I’m taking it anyway. Therefore, I wanna make it better and have it for myself. So that’s why I made this one.

Kyle VanderLeest [00:15:45]:
And the new version we’re bringing out is using all the patented ingredients like new level. We’ll have Genius Pure from NMB and, Solidra Pure, the extract from Rhodiola, the pure Solidroside. So that is fantastic, but nootropic benefits too. That one will probably come in about the version two of that will probably come out in about two to three months. So sort of brand July to August. Okay. Just because of how complex it is. I think ingredient slides, we have like seven, fourteen, like almost 30 ingredients in it, which will make it the best hopefully pre workout on the whole market.

Kyle VanderLeest [00:16:22]:
And, again, getting it right, though, without using, sucralose will be the the harder thing. We’ll probably take a bit longer, but I’m confident now we’ll be able to do it.

Nick Urban [00:16:30]:
One of the things I had mentioned that also I find interesting that no one really talks about is that having a little bit of glucose in your system, whether it’s before a workout or it’s before engaging strenuous mental work, is actually important to deliver the substances and to give your brain and your body the energy. It can even help offset some of the rise in cortisol that that can accompany these things. So the small amount you’re getting from some coconut water powder is probably doing more benefits than detriments even if you’re following, like, say, a strict ketogenic diet. Maybe not hyper strict, but just like a fairly strict.

Kyle VanderLeest [00:17:02]:
I I think it’s pretty common knowledge for those who do follow ketogenic diets to understand that their workout gains are probably not gonna be what they would be if they weren’t following it. The reduction in glycogen stores in your muscles, Lauren, is gonna be a hindrance to your strength. Like, there are outliers to it, of course, but, for me, when I’m on keto or really carb restricted, I do feel flatter, in the muscles, and I definitely don’t have the same strength that I would have otherwise. The other thing as well is carbs are beneficial for creatine absorption. Like, you’ve you you mentioned to me that you don’t respond well to creatine. Well, there could be lots of reasons why maybe creatine transporter genetic thing or, I don’t know. Just sometimes people just don’t respond. But, carbs carbs are used to be people used to combine, orange juice for their creatine back ten, twenty years ago to increase the creatine absorption.

Kyle VanderLeest [00:17:53]:
So, yeah, carbs are very powerful. And even things like glycerol, like, I really like, Hydro Prime as a form of glycerol. It improves, you know, your pumps and the exercise performance. Like, these are really good ingredients for exercise performance. So it really depends on your goal. Like if you want to lose weight and you’re taking a product whilst you’re doing cardio, or whilst you’re trying to lose as much weight, then probably having additional carbohydrates, aren’t going to help you achieve that goal. But if you want to be strong, if you wanna gain muscle, then, yeah, take some carbs. Even if it’s a higher amount, if you’re doing the workout, they’re not gonna be turned into fat.

Kyle VanderLeest [00:18:29]:
They’re just gonna be used in your workout. You probably won’t even see a spike in your blood sugar levels if you’re taking it pre like, within ten minutes pre workout, and it’s not like a like a glucose or something that spikes it instantly. So and even afterwards too, if you take a small amount too, it’s just gonna go into, restoring your glycogen levels in your muscle and never end up being fat. So again, like a U shaped curve, what you’re trying to achieve, carbs are not the enemy that’s for sure. And even honey, like you can use honey as a pre workout thing too. I do that when I feel a little bit low blood sugar.

Nick Urban [00:19:03]:
There’s a book called peak by doctor Mark Bubbs, I think. And he’s talk I think it’s peak. He’s talking about how, like, one of the better ways that endurance athletes fuel themselves instead of using the sports gels is with honey because it has a much much lower glycemic rebound. So your blood sugar spikes up a bit a little bit, not as high, but then it doesn’t crash as low, and therefore, you stay more in the sweet spot and you get better sustained energy.

Kyle VanderLeest [00:19:27]:
Exactly right. I I really like, and I use this in revolution, highly bought it’s called cluster dextrin, HPCD. That has been shown not to spike your blood sugar too much, but it’s very readily available carbohydrate source that doesn’t end up being converted to fat. It will increase the creatine absorptions while I use it. But then as if you were to take that pre workout, you gotta get the benefits of that clostodextrin for, you know, an hour or two hours of, you know, fueling the the using the glucose as fuel for your mitochondria. So that’s, there’s even whole communities. I don’t know how familiar you are with them, but people who follow Ray Pete’s teachings, like they are the opposite end of keto, the keto and peeps and then carnivals, and there’s just so many different things. And every one of them has merit.

Kyle VanderLeest [00:20:12]:
Like, I can’t argue what are the things that the peters say, but then there’s no there’s no, like, no nuance to our insulin resistance. And sometimes they’re wrong on other things, and then carnivals are wrong on other things or right on certain things. So it’s just about, again, going back to what we said in the last episode is measuring where you’re at, seeing how you feel, doing your bloods, doing your hormone testing, and qualitatively and quantitatively seeing how you how you respond to things.

Nick Urban [00:20:37]:
Yeah. Ray P was way ahead of his time on a lot of really trendy topics now, like red light therapy and the sex hormones and estrogen and, what was the other one, PUFAs and omega six, like, seed oils, tons of things like that. But also, like, the mitochondrial or energet basis that, like, bioenergetic paradigm of health and, like, improving cellular energy, reducing cellular waste products, like reactive oxygen species, that kind of stuff. Like, that’s gonna usually do a good job across the board a lot of different things. But how do you actually get there? And I think there’s some individual variation there that there’s the merit in each of the different camps.

Kyle VanderLeest [00:21:19]:
Exactly. Right. And the methylene blue too, he’s the first guy ever heard about methylene blue through. So hat nod to the peak community. That was, that’s been a very powerful ingredient that I’ve used to offset the effects of EMFs. I’ve used it to help repair my mitochondria from malt damage. I use it as much as I, as much as makes sense or neuprofen benefits. Yeah, it’s just one of these ingredients I really like.

Kyle VanderLeest [00:21:43]:
And also the anti parasitic and anti fungal effects it has when you, you know, take it in a capsule instead of just sublingually for the brain benefits. It’s really cool ingredient, and I love that it’s gaining it’s one of these ingredients that’s gaining mainstream popularity. I think Kennedy was putting it on the plane and now everyone’s talking about what it is. And that’s a really cool ingredient. And we’ll be bringing that out with level up soon as well.

Nick Urban [00:22:04]:
Oh, really? And and what delivery mechanism is that gonna be?

Kyle VanderLeest [00:22:07]:
In a capsule, interestingly. Everyone’s doing it in droppers, and there’s plenty of them available, but I really like it in capsules. I’m gonna combine powder? Yeah. Powdered. I’m gonna combine it with functional fillers, c l l carnitine, PQQ, and Ubiquinol, just a mitochondrial Oh, nice. Yeah. That’ll be out in probably two weeks’ time.

Nick Urban [00:22:26]:
Wow. Okay. That’s cool. I was looking for a source of methylene blue powder a long time ago. Very hard to find high, like, pharmaceutical grade methylene blue powder. It’s much easier to find in liquid form. Cool that you found it, and I was actually gonna suggest that you come out with a mitochondrial optimization stack, but you already you already are.

Kyle VanderLeest [00:22:45]:
There it is. Oh, nice. Flavor. It’ll be cool. I really like it. And, I’ve used a few other brands’ liquids. I’ve used transcriptions. If you want to use a trash, that’ll work better for nootropic effects directly, you know, goes to your brain, that one.

Kyle VanderLeest [00:22:58]:
So I’d never say don’t use theirs over this. This is just going to be a general, like we could take it daily or you, you know, might help with, for for me, I’ve had issues with candida having lived in mold, so it has that dual benefit for that effect. So, yeah, it’s just, again, like, I take all these things and like, you know what? I probably should just make this myself. That way I can be sure of the quality and I can have plenty of it for myself without having to rely on other companies.

Nick Urban [00:23:23]:
I like that. So I wanna talk about this product right here, Total Recomp. I have it in front of me. I got it because I was looking at the ingredient profile like I often do. And as soon as I saw certain things in the label, I immediately became fascinated and have been playing around with it a bit. Tell me why you chose DNF ten peptide and then also s l u p p three three two and t two. Those were the ones that really caught my eye, and perhaps there’s others there that I should have also taken as much interest in, but those were the ones I found the most fascinating in this formula.

Kyle VanderLeest [00:23:57]:
Now they’re the heavy hitters. You’ve you’ve nailed it with that one. So the DNF 10 is, so it’s derived from it’s hydrolyzed peptides derived from, saccharomyces cerevisiae, a a yeast that is is pretty well studied too, to support satiety, to help your metabolism, and is basically an appetite suppressant. That’s primarily the, the main reason I use that one. It’s it was in like, what you have in your hand is the version two. Version one, I didn’t I had DNF 10, but I also I did not have the other peptide called SLU p p three three two. That is a small molecule, but everyone thinks it’s a peptide. Thank you for that.

Kyle VanderLeest [00:24:44]:
Little question that steered me on the right direction. That one works via agonism of the estrogen related receptors. And, essentially, like, just as a one sentence summary, it’s like exercise in a pill. It will give you the effects of exercise. It’s one of these exercise mimetics similar to El Baba, that essentially helps with AMPK activation, helps fat loss, thermogenesis, reduces fat mass, and it’s, you know, combined with all the other things that I put in it to support thyroid health, to support blood sugar, and glucose disposals, to support, glycolysis via, like, LCAR and GBB. It just essentially, again, we spoke better than the last one. How do I formulate? Well, I reverse engineer all of the processes that I feel go into fat loss, for example. Their their ingredients for appetite suppressant, their DNF ten, is the primary one for that.

Kyle VanderLeest [00:25:43]:
Thermogenics, things like albaba can cause sweating. I was gonna use tesafencine in it as well, but having used that one as a stand alone and had not such great effects, I chose not to, thankfully. Exercise mimetics, thyroid supporters, and just, like, it was my attempt at losing weight. Because when I lived in mold, I unfortunately, it’s just how it works. You develop leptin resistance to with chronic mycotoxin exposure Despite having a really good diet and trying exercise, despite my adrenals being cooked from constantly having toxin exposure, I did gain a bit of weight. So this was my remedy to that. Grains of paradise is just I’ve put so many different things into that formula to try and, support weight loss that I’m really, really proud of it and really liking the benefits so far for myself. I don’t know what you’ve experienced from it.

Kyle VanderLeest [00:26:29]:
You hadn’t shared that yet, but, in, intellectually, it seemed pretty good on paper. Hey.

Nick Urban [00:26:35]:
Yeah. And so you mentioned the SLU p p three three two works on estrogen. I think that’s gonna come across as a bit of surprise to people that estrogen also can be like exercise and a pill and exercise mimetic. Can you break that down a little more?

Kyle VanderLeest [00:26:50]:
So it works on estrogen estrogen related receptor alpha. So there’s so many different mechanisms for how estrogen works in the body. We spoke about it in 2023, but turkesterone actually works on estrogen receptors too. That helps with muscle growth. But estrogen related receptors, it’s not all bad. Like, estrogen estrogen as a, hormone is associated with softening, with weight gain if you’ve got excess amounts of it. But, like, everything has its own sort of way that it can work in your body and specific subsets of these receptors. Like, there’s alpha beta.

Kyle VanderLeest [00:27:24]:
There’s, different ones like that. And it works on this one specific thing. It’s like a serum. And even things like I’ve forgotten. It’s from soy isoplavones. They’re serums as well. Like soy, I would avoid like the plague, but the, active constituents from that might have certain benefits for things like estrogen receptor positive cancers, for example. So it works by that effect to then downstream work on AMPK as the primary thing, but it also has effects on PPA.

Kyle VanderLeest [00:27:56]:
It’s a PPA, RN agonist, I believe. Sorry. I’m just trying to get into the weeds on this time and not sort of cross tangle my mechanisms too much. But yeah, and mitochondrial support too. It really helps up regulate, what is it enhances mitochondrial function and exercise endurance by improve increasing your metabolism?

Nick Urban [00:28:19]:
Yeah. So I played around with it at a bit higher of a dose, and I do notice that it has, like, a number of different effects. With things that are gonna overclock your mitochondria, so to speak, to up regulate its function, maybe in perhaps in your new stack, are you adding anything? Because, like, if you drive faster, your car might create more exhaust and your mitochondria might act similarly when you’re creating more energy, you’re gonna have more byproducts. And if you’re not very healthy or on optimal health, all your pathways aren’t working properly, you might create that more cellular exhaust with reactive oxygen species. Are you adding anything into your formulas to, like, help mitigate that and make it easier on the body?

Kyle VanderLeest [00:29:01]:
Not necessarily. And this is a nuance to fat burners too. If they work too well and you’re losing fat really fast, then often you as well as, you know, you end up with a lot of accumulated toxin soon being liberated, and then then it puts a burden on your liver and has to be cleared. One of my good friends, and it was quite overweight, and when I put him on a a, a really good diet, he lost a heap of weight. But then he looked really sick because he had a lot of accumulated, toxins in his fat. So any weight loss program, any, fat burner that actually works is going to potentially if you’re not porting your clearance of toxins with liver support or, take doing regular saunas can actually result in you not feeling as good because of the stored toxins in the fat. As far as kicking up reactive species, it I feel like that only will occur if you’ve got issues with metals as well, like, not just intracellularly stored, but anything that impairs mitochondrial function. And this is where we go to look at your organic acids tests to see how your Krebs cycle is functioning, to see how your electron transport chain is functioning.

Kyle VanderLeest [00:30:10]:
And in an optimized system, you should be able to push the the pedal down on the accelerator without breaking anything. But it’s it’s one of those things, like, you do need more energy, and more energy often results in increased repair, increased mitogen mitochondrial biogenesis, increased synaptogenesis, improved healing. So it’s one of these things where you wanna push it as high as what makes sense, but then if you push it too far and you have inefficiencies in the system, they’re probably something that you need to deal with. Heavy metals, microplastics, estrogen mimicking, things for, like, tap water, all all the other things that people would need to detox, that could be causing the root cause of issues that aren’t just associated with fat gain, but are associated with disease processes. We spoke about this offline before one of before our episode, and we spoke about cancer. And I mentioned, like, what causes cancer, what I think causes cancer anyway. It’s carcinogens. It’s forever chemicals.

Kyle VanderLeest [00:31:10]:
It’s microplastics. It’s, things like glyphosate and pesticides and heavy metals. All those things are directly clogging up your mitochondria. It’s reactive nitrogen species from EMF. It’s excessive reactive oxygen species from maybe too much polyunsaturated fat consumption. It there’s so many things that go into it that I don’t feel like peptides or even fat burners are going to cause problems with that or things like dye hexa, for example, it’s the combination of you still having the things that are impairing mitochondrial function in your cells, in your fat, and then trying to push other things whilst not dealing with the real, I guess, root cause of the problem and why you have mitochondrial dysfunction in the first place. If you have really healthy mitochondria, I don’t see there being anything in this that’s gonna push you to the point of breaking or to have, quote, unquote, bad dirty off gassing or dirty fumes coming out of your exhaust. But if you do, then, you know, again, like like any good product, right, you’re pushing something.

Kyle VanderLeest [00:32:18]:
It can come at a cost. Like, if you’re a finely tuned formula one car versus a 30 year old car that’s been serviced once, you know, it’s not gonna be, it’s not comparable. Right? Like, we optimally, in health optimization, try to get ourselves to that level of we wanna be the Ferraris of the world. We wanna make sure we’ve got the best wheels. We’ve got the best engine. We don’t have we’ve got the best fuel that’s not full of toxins. You know? Like, we don’t want ourselves to be anything other than optimal, and that’s when using these things like neuroregenerate for boosting brain function or using Total Recomp for improving mitochondrial function. We wanna be able to take these without there being consequences.

Kyle VanderLeest [00:32:54]:
So there’s a lot of foundational things that I think level up products don’t necessarily address that I think need to be addressed first, and that’s just nutrition. Like, a multivitamin is gonna be great. Doing some level of detox if it’s warranted, I think most people, it is warranted nowadays. Doing sauna, doing exercise, movement, rebounding, lymphatic work, all that’s really important. And then a lot of these products are kinda just like the icing on top of the cake, really, for people’s health. It’s like, if you wanna take it to that next level once you’ve got the foundations right, then these are just gonna be phenomenal. But, again, like, everyone’s different. Everyone’s bio individuality, toxic load, and, mitochondrial function’s gonna be different.

Kyle VanderLeest [00:33:33]:
So, yeah, long winded way of saying, I don’t think it’s gonna hurt you, but, you know, if you’re full of toxins, might not feel particularly good on it. Who knows?

Nick Urban [00:33:42]:
Yeah. I hate that I keep coming back to the fact that detox is increasingly necessary. And not only will you cap some of the downsides that you experience if you didn’t have that toxic burden, but also if you’re looking to get to a high level of performance, then the more toxins you have in your body, the more noise there is, the less you’re able to discern the signal and you’re just like having to take a bunch of things just to try and get back to baseline. But if you don’t if your baseline is already clean and clear, then everything else you add is more effective to begin with.

Kyle VanderLeest [00:34:16]:
If if I could only do one biohack, it would be sauna. Like, that’s just gonna do so many things for everything. I’ve upgraded my sauna recently by putting an ozone generator within it and kind of making my own at home. My is a really cool ozone sauna where you bathe in, like, 50% ozone, and it is their marketing claim is it’s seven times more powerful than a regular sauna. And from looking at the stuff that comes out on your towel, like, I’ve got mycotoxins galore to get rid of. So it’s making a very significant difference to my and my partner’s health since adding the ozone to it. Sauna will accomplish that. You just probably need to do a lot more of it.

Kyle VanderLeest [00:34:50]:
But other things, rebounding lymphatic drainage Wait.

Nick Urban [00:34:53]:
Wait. I’m curious. You you built your own HOKAT. Do you have, like, a is there a guy that you followed, or are you just I’m guessing you’re not pumping ozone into your sauna and that you have, like, some kinda setup that keeps your head outside of the unit or something?

Kyle VanderLeest [00:35:06]:
I have a Ceracide, one of those portable tent ones, the full spectrum. I don’t know if you know the brand, but they, yeah, have the, near and far infrared in it. Your head sticks out. I seal it up with a towel, so I’m not breathing in ozone, have a fan in case it comes out and then inside of it, so zone and it’s kind of less safe than if you were at a hoe, at a hoe cat, which is a hard shelled sauna, but, you know, for compliance and not having to drive an hour each day there and back to a clinic that has one, if you can have your own hoe cat at home, fantastic. You’ve got a lot of money, probably because you’re like $60,000 but this is only like a $1,500 setup for me to be able to do that. And I’m really started recommending it provided people do their due diligence. Cause if you breathe in ozone, your lungs are not going to like you at all. I’ve done that.

Kyle VanderLeest [00:35:51]:
And actually with coughing like, three or four days and did a bit of lung damage. Not from doing the sauna. I was clearing out some mold in a past home and had to run back in, but ozone is incredibly beneficial for the body and are fantastic. I’ll sing their praises for the coming years, I’m sure, because of all the benefits I’ve got from that.

Nick Urban [00:36:09]:
Yeah. I’m a big fan of ozone. I have an ozone therapy system. I use them in a bunch of different forms, and I also use sauna. I haven’t combined the two because I didn’t realize you could create your own HOKAT at home. That’s a cool system. I’m gonna have to look into that.

Kyle VanderLeest [00:36:21]:
Make sure it’s sealed up, and don’t use it in a wooden one because obviously, you’re gonna breathe the nose zone and not have a very good time.

Nick Urban [00:36:27]:
Yeah. I thought you were, like, you had, like, a mask on your I mean, your eye. You you don’t wanna get ozone on your eyes either. So I guess you don’t really have your head has to be outside of it and there has to be a seal of some sort.

Kyle VanderLeest [00:36:39]:
Yeah. The whole cats, you have your head hit sitting out as well. And in my little therisage or equivalent one, you could do the same thing provided at seals though. The good thing about theresage is it’s very well sealed. So yeah, it it’s it’s being very safe at the moment. Like, I’m not putting out medical advice for people and I don’t want people to hurt themselves. Please be careful with it. But, yeah, it’s it’s certainly one way to supercharge your saunas.

Kyle VanderLeest [00:37:03]:
And then you combine things like tote care and nap to support your liver while you’re in the sauna. Taking a really good binder is something that’s really helped me as well. I’m working on my own, but for the most part, like, it’s not gonna be too dissimilar to what Quicksilver scientific or CellCore have. There’s a really good as well. So anything with, anything with, with bentonite clay, I really like activated charcoal and, chitosan, chitosan or yeah. It’s cholestaramine, it’s a pharmaceutical one that is stronger than chitosan, but chitosan is just derived from mushrooms and it binds bile. So when you are clearing mold, one of the primary ways in which mold is cleared is through bile, and that’s why TUDCO is so powerful for mold detoxification. But then on the other end, if you’re pushing it out without it being cleared properly, a a chitosan or cholestaramine can really help clear that.

Kyle VanderLeest [00:37:51]:
So that’s why they’re used in, MCAS and SIRS and mold illness, that cholestaramine is. But chitosan is like a more gentle, natural way of doing it. I really like modified citrus pectin too for that as well as zeolite. I’m a little bit fifty fifty about.

Nick Urban [00:38:07]:
And why is that?

Kyle VanderLeest [00:38:09]:
I’ve heard, like, even less it’s, like, really, really, really pure and this applies to, I guess, a lot of the binders that you can actually be ingesting heavy metals and toxins that like, it’s already bound to a metal, and then you put it in a capsule and then just take a binder with a metal in the capsule versus it needs to not have it needs to be tested for purity. When I bring out a binder, it will definitely have all the purity reports for metals. That’s definitely another reason why supplement quality is important.

Nick Urban [00:38:34]:
Frustrating, but it is the way it is. Have you played around with CO two therapy at all? Like, I was thinking perhaps pumping it into your sauna as, like, another gas you could play around with.

Kyle VanderLeest [00:38:44]:
Can Jane, interestingly, when I worked at the hyperbaric center, the director had CO2 therapy that he was going to play around with. And he had nitrogen as well. So, but I never actually hung around long enough to see how that resulted as far as clinical outcomes for the patients. I don’t think he yeah. Anyway, I haven’t tried I haven’t tried either of those. No. But I have seen the c o two saunas as well. Have have you tried those?

Nick Urban [00:39:08]:
No. I I haven’t, but I’ve been looking into different ways of administering c o two. Like, obviously, you can breathe it, but then also there’s a suit you can wear that I’ve seen that some people get claim to get good results from. I don’t know. I haven’t actually used it, and I’d be curious what it yields for people if it’s actually worth using because it’s a pain to put a suit on and pump it full of CO two and then hang around in the suit for a while. And so I was curious if you had used that at all.

Kyle VanderLeest [00:39:35]:
I think the Right Pete forum would probably have something on that. They’re a really big fan of CO two as well to nod our heads to them again.

Nick Urban [00:39:41]:
Yeah. Exactly. That’s probably why I came across it a long time ago. In your Total Recomp formula, you have t two, and people tend to use t three and t four for thyroid support. I’ve only come across one other person that has a t two supplement a long time ago, and it seems like it has some pretty unique properties as compared to the others, which are also regulated and unavailable over the counter.

Kyle VanderLeest [00:40:03]:
Yeah. Well, I’ve played around with, again, Ray Pete using, topical t three and t four and for fat loss. Using it was really good, but then I don’t wanna downregulate my own endogenous thyroid function. And, yeah, I don’t wanna mess with my own thyroid. Like, getting that right, it’s a really good kick start to use those ones. But the reason I really like t two, is because that’s, like, the form it gets converted from inactive t four to active t three, and then intracellularly, it becomes t two. So t two doesn’t mess around with that feedback loop that from TSH to t three. And you can bring it in to sort of jump start, to help thyroid work intracellularly and to help mitochondrial function.

Kyle VanderLeest [00:40:48]:
So that’s primarily why I like it. And as a weight loss, a thyroid was the best thing that I’ve ever used as drops. So I’m like, well, t two has a very high safety profile. It’s in microgram amounts. It works orally, and it’s not highly regulated like these other ones. So I’m like, well, that just makes sense. I’m trying to support people’s thyroid health because this is often something that every like, a lot of people have issues. You hear, like, almost comically, people say, oh, I got a glandular problem.

Kyle VanderLeest [00:41:15]:
Well, that gland is probably the thyroid, and your problem is you probably got fluoride and and chlorine and bromide and all those other things preventing iodine from eating and maybe, a, tyrosine deficiency, if you’re vegan again. But, yeah. I really liked it too. It works. It worked really well for me when I used played around with it in isolation. And, you know, I just wanted people to feel the benefits of having an optimal thyroid because when it comes to feeling energized, like you can artificially inflate it with caffeine or nootropics, like you can almost artificially or just transiently feel really energized from them, but it doesn’t last versus my last, but not as well as having a proper functioning thyroid, like anyone who’s had thyroid issues there, they’ve got malaise, they’ve got fatigue, they’ve got brain fog. Iron deficiency is one of the big drivers of it, iron and iodine deficiency. So bringing in T2 is a way to kind of give you that energy and to help the thyroid work better without actually having to use iodine, because I don’t like supplementing iodine for the general population.

Kyle VanderLeest [00:42:22]:
It’s a bit of a double edged sword. It might be someone’s absolute savior and it might, you know, cause some, you know, thyroid autoimmunity to be worsened or something like that. So I don’t use that. So I use selenium, and the t two in this one to try and support. And colius for scoliosis, a really good herb that helps support the thyroid as well. And yeah, when you have a really good working thyroid, your metabolism is going to be higher again, like similar to the, what we were talking about before, where if you get things working better than you can definitely have some other issues with it. But, yeah, I really liked using t two. I don’t know how what your experiences were using it, but, it is a lot safer than using those other ones because of no risk of suppression or minimal, if any, risk of suppression.

Nick Urban [00:43:11]:
Coleus Forscholine, that’s used in, like, the classic nootropic stack called CILTEP.

Kyle VanderLeest [00:43:17]:
Is it? Okay. Didn’t know that. Yeah.

Nick Urban [00:43:18]:
I think, like, one of the one of, like, the early nootropic stacks from, like, I wanna say, ten, fifteen years ago, the premade ones, It was that and a couple other things, and it was called, like now it’s made by natural stacks. It’s called, like, neurofuel or something, but that’s the first time I came across that. So it I guess some nootropic effects out of Total Recomp as as well.

Kyle VanderLeest [00:43:36]:
Yeah. Well, I didn’t I mean, I knew for Skollin had a modest level of, benefit for the brain, but yeah. And if it’s in a nootropic sack, it must be a bit better than I thought.

Nick Urban [00:43:46]:
Alright. I wanna go into your longevity formula now too, because you had some of the typical things that I see in a lot of longevity stacks, and that is, like, NAD precursor, like NMN or NR. You also added some other things in here such as quercetin and fisetin, but then also terestilbene and JBSNF and apitalon. And apitalon was, like, is, like, one of the ones I’ve haven’t seen in an oral formula. I’m not even sure if is it orally bioavailable?

Kyle VanderLeest [00:44:19]:
Yeah. It is. It’s small enough. It’s below that 500 kilo Dalton range that it will work orally. It’s just, again, you have to be a bit smart with how you use it. It might degrade a little bit. So it is dosed relatively high. And, again, you asked how I dose things in the last one.

Kyle VanderLeest [00:44:31]:
Well, understanding the bioavailability of things like, you can use less Naset because if it’s greater bioavailability versus NAC at only one or 2%. Or with peptides that don’t have great absorption like GHK or, epitalon, I dose it higher sort of allowing for, like, that potential of loss of about 50 to 60%. So if you’re only getting forty percent of the dose, you’re still in that clinical that that, effective range. But, yeah, I used to pit alone because that is fantastic for, ex I think it’s for telomeres, in, in how it has its effect. It’s meant to, prevent the breakdown of telomeres or even extend telomere length in some studies. I don’t know if they’ve been replicated, but there was one back a few years ago that said it was really good for that. And the other obviously, I use the precursors to NAD and longevity. I think they’re great.

Kyle VanderLeest [00:45:26]:
There’s so much evidence behind them for boosting, your NAD pools, but the novel and unique way that I like to increase NAD is by inhibiting the NNMT enzyme. And this enzyme is what breaks, what clears NAD, to oh, forgotten. I didn’t I needed to brush up on this before we spoke it up. It it’s basically it recycles, NMN back into the NAD salvage pathway and is capable of increasing your NAD levels better than the precursors would just by keeping it around kind of like how huperzine a increases the ciel choline. It doesn’t provide choline like alpha GPC might, but it, it prevents the enzyme from breaking it down so it hangs around longer. Well, that’s pretty much what the five amino one m q and the j b s n f triple zero eight eight small molecules do. And, yeah, they increase your pools, your overall NAD levels, your NAD pools, promote mitochondrial biogenesis, metabolic function, all the things that NAD does. But, also, using fisetin and apigenin, they’re really good for reducing cellular senescence, associated with DNA rep like, protecting your DNA from from, damage, helping with, protect TLMs.

Kyle VanderLeest [00:46:49]:
And I think that’s what a pit of the reason why I use a pit alone as well, the the TLM, protection and even extension potentially.

Nick Urban [00:46:57]:
Yeah. The five amino one m q is also used for athletic performance. And I think it was Ryan Smith of now True Diagnostic mentioned that he did a two week cycle of it or something and increased his vertical jump by some ridiculous amount, like 14 inches or something.

Kyle VanderLeest [00:47:14]:
Look, I haven’t personally had that level of benefit from it. I think it’s just one of those things that, and kind of like, if you were to take an ad, you would notice some level of improved energy. I think it’s like, if you took a really, really, really good prolonged dose of NAD, but it works a lot more it works a lot quicker because you don’t kinda have to build up the pool as fast. I think by inhibiting the clearance of it, you’re able to build up your NAD pools faster than if you just take all the precursors to it. So that’s why I think it’s really good at increasing your mitochondrial energy production and, I guess, for his vertical jump, by having increased mitochondrial biogenesis and increased NAD levels, he’s gonna have, you know, improved power output. So but I don’t I make no claims about vertical jump in increase improvement from taking, five amino, but, yeah, that’s cool anecdotal. And, again, like, maybe he never had taken NAD or NR, and he just jumped on, five amino. So his first it’s the first time using something that’s gonna increase, NAD levels.

Kyle VanderLeest [00:48:16]:
It’s pretty profound versus if you’ve taken those other things and you’ve already built up your NAD pools pretty well with NMN, NR, or even the, IB infusions of NAD, then you might notice the effects of bifib amino or JBS NF, as much as if you you’re just new to it. So, yeah, they’re just new oral ways to increase NAD levels. I still think probably the best way would be to do the IBs, but, Yeah. I really like these ones as as as, tools oral tools to deliver the, you know, a clinical effect.

Nick Urban [00:48:50]:
I will have the bottle in front of me, but is there a recommended time to take this? Because I think that five amino m one m q is one of the ingredients that impacts the circadian clock genes.

Kyle VanderLeest [00:48:59]:
Okay. I always take it in the morning with my, with my morning stack, anything that increases energy, I don’t really wanna be in bed feeling energized. Not that it’s like a caffeine, but, yeah, I just always do it in the morning. Usually do neuroregenerate in the morning, total recomp and longevity all in the morning with, with my coffees or if I don’t have a coffee, just with my morning mix.

Nick Urban [00:49:20]:
Can you absorb all those substances at one

Kyle VanderLeest [00:49:23]:
time? Your your intestines are the size of a tennis court. We can man manage a few micrograms because they’re in such small quantity. And most of them, because they’re small enough, they honestly just passively diffuse across if, you know, that if they’re below their 500 kiloDalton. If they’re a bit larger than, with other liposomes, they’ll they’ll get across that way. So, yeah, you know, definitely.

Nick Urban [00:49:45]:
Well, that’s reassuring. It makes it easier for everyone who doesn’t wanna have to spread their supplements out every two hours throughout the day.

Kyle VanderLeest [00:49:51]:
The nuance will be you can’t absorb, like, 30 peptides through your skin because you’re putting it on this small little line. Like, if you were to do topical peptides, we’ve been trying to do a skincare product using eight of them and realize that, okay, well, they kind of compete for absorption in this small area. But when you’re talking about your ileum, your D your small intestines, that’s like so much, area for absorption, you know, with all the villi and micro villi that are in there that it’s no such issue. Mhmm.

Nick Urban [00:50:21]:
Yeah. And I don’t know if you’ve seen this. There’s actually a paper done by Cavinson, the Russian professor, about Apitalon. He’s the guy who popularized that research. But he did one on Apitalon, and I think it was Fiameline. And it was a long trial. I think it was a bioregulator forms of them. So the oral don’t quote me on that actually.

Nick Urban [00:50:42]:
It might have been injectable. But it was some insane improvements to all cause mortality, the risk of dying from anything. Over, like, six years later, it was, like, I I don’t actually I don’t even wanna say the number, but it was something outstanding. So I’m not sure if you can get that into a capsule, but it might be worth considering in in this as well to help, like, with the health of the thymus gland in the longevity stack because thymus is something that degenerates with age, obviously.

Kyle VanderLeest [00:51:08]:
Which one was that again? Sorry. Thymosin.

Nick Urban [00:51:10]:
Oh, this one was Thymolin, t h y m u l I n.

Kyle VanderLeest [00:51:14]:
Alright. I’ll have a look at that one. But, yeah, he did a majority of the bioregulated research and, yeah, it did find, extension of lifespan pretty reliably across, you know, different, protocols using those. He did a lot of work on, or him or the university that he was associated. Also did a lot of work on GHK because they used to think or it still argued that it, it might be a bio regulator as well. But yeah, the epilon is the one that in animal studies showed like a 30% increase in lifespan on like, right. Rats and mice called them rice together, rats and mice. And yeah, the telomerase, activity, what is it that it helped to elongate the telomeres? Sorry.

Kyle VanderLeest [00:51:59]:
I was losing that earlier when we’re trying to talk about it, which is meant to, reverse, reverse cellular in essence. So the thylene, I believe is not a bioregulator because of the length of it though. So it might be, okay.

Nick Urban [00:52:15]:
Yeah.

Kyle VanderLeest [00:52:15]:
I’d have to have a look at the I mean, I can do it in the background now while we’re talking.

Nick Urban [00:52:19]:
Here’s here’s the study. It says, thymolin combined with epithalamin, which is the natural form of epithalone, I think. As compared to the control group, they, they were treated with it annually for six years, and they had a 4.1 fold mortality decrease in that group as compared to the control fold mortality decrease in that group. I’m not sure final one’s a bioregulator, though.

Kyle VanderLeest [00:52:43]:
I’ve just had a look at it, and it’s, 843 kilodalbins. So it’s probably be a bit too large unless you would a liposome it or take it with something that increased. It’s it’s close enough that it possibly could work orally, but, like, a lot of the Russian research was done, on injectable stuff. So that one probably did. Yeah. The acute one’s really short chain, and most of the bioregulators are are, like, two amino acids or three amino acids. So all of them Yeah. But maybe there’s probably one or two exceptions that I can’t think of do work orally, and that’s why bioregulators are great.

Kyle VanderLeest [00:53:12]:
My, friend, Nat Niddim is probably the primary educator on bioregulator peptides in the world at the moment. So she could be a, a follow-up episode if people wanted to learn more about that. She knows a lot more than I do.

Nick Urban [00:53:24]:
Awesome. Well, Kyle, anything else you want to discuss? I mean, there’s a lot of other things in your wheelhouse that we could touch on. I know we’re getting run running low on time again. Where would you like to point people if they want to give any of these formulas we’ve discussed so far a shot? Or perhaps if you wanna listen to the other things that are the most popular and people you get the most glowing reviews and anecdotes about, you can point them to those as well.

Kyle VanderLeest [00:53:49]:
Yeah. Well, GR Repair is a hero product. We’ve got thousands of positive reviews on that now. It has so many things for gut health that it works pretty, pretty, unanimously across the board, but I would actually point people to the new peptide cheat sheet card that I’ve, it’s not even a cheat sheet. It’s more of a comprehensive peptide reference guide. Now that last year’s version was shortened weight. This one’s like really detailed. I’ve got a section on it, which has, like, the top peptides for brain health or, body composition for injury recovery, antiaging.

Kyle VanderLeest [00:54:23]:
It’s basically listed what they are and what they do. And then after it, if you wanna get nerdy like us and find all the mechan like, a basic summary of the mechanisms and a bit more about the peptide, we’ve got that in it as well. And then on the front page is over 50 peptides and small molecules, as well as the health systems that they, you know, are associated with helping, you know, everything from all the injectables to the only thing I left out on that one were the topicals. I’ll do, like, a separate guide for that one. But, yeah, there’s from CJC, epimoralen, tesamoralen, Apidolon, BPC, KPV. They’re all on that one, and it’s a it’s a free download if people wanna learn about them. So I’ll direct people in that way. And then if they ever wanna try them, a a lot of them are in the, health products.

Kyle VanderLeest [00:55:09]:
So we’re a a good source of those. Otherwise, injectables, there’s plenty of good vendors you can try, online. I don’t know if you’re personally associated with anyone, but there’s, a few that I know that I can steer people towards if you’d like. Otherwise, I’ll let you do the guiding from that end.

Nick Urban [00:55:25]:
Sure. And then do you have the link for that ready, or should we just put that in the show notes for the episode?

Kyle VanderLeest [00:55:31]:
I’ll I’ll make leveluphealth.com/urban your landing page where people can download that and they will get your discount code there as well.

Nick Urban [00:55:40]:
Cool. And I will also put that in the show notes in case you guys are driving or busy and unable to write that down. Kyle, thank you for joining me again on the podcast. Before we part ways, a couple other final questions for you. And that is, I was gonna ask this in the warm up, but I decided to hold off until the end. Are there any unusual molecules that you’ve consumed so far today?

Kyle VanderLeest [00:56:04]:
Today’s, not unusual anymore, but methylene blue, for sure. High dose of catawaba bark. My friend Lucas ergogenic health has released that and that’s synergizes really well with some of the dopaminergic things that I have. And, it’s like a stimulant free caffeine. So head nod to him for using that one. And I did the whole cat before this, so I’m a little bit a little bit hot and bothered, but yeah. Yeah. I’ll definitely recommend that again.

Nick Urban [00:56:32]:
Well, perfect. And then if people want to understand your methodologies and what’s informed your approach to health optimization, perhaps formulation, are there any teachers or books or resources you recommend?

Kyle VanderLeest [00:56:47]:
The same as before Ben Greenfield books, like the basics, new books. I I’ve got a toddler, so I basically haven’t had any time to read anything in the last two years. And the level that I’m at now, I kind of just dive into science more so than I do actual resources and books. If people do wanna learn more about peptides and become practitioners, this the, I think it’s William Seeds has a peptide, well, how would I describe it? A certification in peptide, therapies. A four m are doing a lot around peptide therapies as well. And, honestly, I think coming to places like the Health Optimization Summit, Hack Your Health, there’s always a good showing of, of vendors will be at those ones. You can meet me personally at the one in Austin and at the a four Ms, but I really feel like if people wanna learn more about peptides, a four Ms really good as well as, seeds Institute. So, and our website has a lot of content on it as well.

Kyle VanderLeest [00:57:46]:
We’re really building out a directory guide for peptides for people, as well as all the ingredients that we use in the formulations, sort of what makes them unique, what makes them beneficial, what they might be helpful for. So that’s where I’m putting a lot of my effort into my son and building out the website, making it kinda like the, biohacker’s guide to supplements and peptides.

Nick Urban [00:58:05]:
Beautiful. Well, I’ll see you at the event in Austin. When you say that you’re going into the science, are you talking about, like, looking through each of the studies on PubMed, or do you have a different way of approaching it that you prefer? Do

Kyle VanderLeest [00:58:18]:
you know the best place that I find new ingredients are actually the forums, and then I’ll go on to find the science because it’s easier to have like an army of people who are all on the cutting edge, trying to find the new best thing. And then a lot of the peptide forums on Facebook does, Hey, has anyone tried this? And I’ll maybe get some anecdotal experience saying it’s amazing. And then I’ll go on and go to pub med and yeah. Have a look around and see what the mechanism and how that might work. And then I’ll put suppliers so I can then find why that might be fantastic and go from there.

Nick Urban [00:58:50]:
I like that. That’s exactly what I do too. And that’s been the OG way of doing this bodybuilders back in the day of like scrolling, perusing the all the old forms and finding latest things and actual anecdotes of what works and what looks great on paper but doesn’t work. Alright, Kyle. Thanks again, and we’ll all see you in Austin shortly.

Kyle VanderLeest [00:59:08]:
See you soon, Nick. Thanks again.

Nick Urban [00:59:10]:
Thank you for tuning in to this episode. Head over to Apple Music, Spotify, or wherever you get your podcasts and leave a rating. Every review helps me bring you thought provoking guests. As always, you can find the show notes for this one at mindbodypeak.comslash, and then the number of the episode. There, you can also chat with other peak performers or connect with me directly. The information depicted in this podcast is for information purposes only. Please consult your primary health care professional before making any lifestyle changes.